CRISPR/Cas9 and genetic screens in malaria parasites : small genomes, big impact

The ∼30 Mb genomes of the Plasmodium parasites that cause malaria each encode ∼5000 genes, but the functions of the majority remain unknown. This is due to a paucity of functional annotation from sequence homology, which is compounded by low genetic tractability compared with many model organisms. I...

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Detalles Bibliográficos
Autores principales: Ishizaki, Takahiro, Hernandez, Sophia, Paoletta, Martina, Sanderson, Theo, Bushell, Ellen S. C.
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: Portland Press 2022
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/12437
https://portlandpress.com/biochemsoctrans/article/50/3/1069/231360/CRISPR-Cas9-and-genetic-screens-in-malaria
https://doi.org/10.1042/BST20210281

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