Chalcones in Bioactive Argentine Propolis Collected in Arid Environments
The aim of this study was to assess the chemical and biological profile of propolis samples collected in arid environments of north-western Argentina. The samples were from two phytogeographical regions (Prepuna and Monte de Catamarca Province). Propolis ethanolic extracts (PEE) and chloroform (CHL)...
| Autores principales: | , , , , , , , |
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| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
| Publicado: |
Sage Publishing
2022
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/12346 https://journals.sagepub.com/doi/abs/10.1177/1934578X1200700718 https://doi.org/10.1177/1934578X1200700718 |
| _version_ | 1855036739837493248 |
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| author | Solórzano, Eliana Vera, Nancy Roxana Cuello, Ana Soledad Ordóñez, Roxana Mabel Zampini, Iris Catiana Maldonado, Luis Maria Bedascarrasbure, Enrique Luciano Isla, María Inés |
| author_browse | Bedascarrasbure, Enrique Luciano Cuello, Ana Soledad Isla, María Inés Maldonado, Luis Maria Ordóñez, Roxana Mabel Solórzano, Eliana Vera, Nancy Roxana Zampini, Iris Catiana |
| author_facet | Solórzano, Eliana Vera, Nancy Roxana Cuello, Ana Soledad Ordóñez, Roxana Mabel Zampini, Iris Catiana Maldonado, Luis Maria Bedascarrasbure, Enrique Luciano Isla, María Inés |
| author_sort | Solórzano, Eliana |
| collection | INTA Digital |
| description | The aim of this study was to assess the chemical and biological profile of propolis samples collected in arid environments of north-western Argentina. The samples were from two phytogeographical regions (Prepuna and Monte de Catamarca Province). Propolis ethanolic extracts (PEE) and chloroform (CHL), hexane (HEX) and aqueous (AQ) sub-extracts of samples from three regions (CAT-I; CAT-II and CAT-III) were obtained. All PEE exhibited antioxidant activity in the DPPH radical scavenging assay (SC50 values between 28 and 43 μg DW/mL). The CHL extract was the most active (SC50 values between 10 and 37 μg DW/mL). The antioxidant activity in the β-carotene bleaching assays was more effective for PEE and CHL (IC50 values between 2 and 9 μg DW/mL, respectively). A similar pattern was observed for antibacterial activity. The highest inhibitory effect on the growth of human Gram-positive bacteria was observed for CHL-III and CHL-I (Monte region) with minimal inhibitory concentration values (MIC100) of 50 to 100 μg DW/mL. Nine compounds were identified by HPLC-PAD. Two of them (2′,4′-dihydroxychalcone and 2′,4′- dihydroxy 3′-methoxychalcone) were found only in propolis samples from the Monte phytogeographical region. We consider that the Argentine arid region is appropriate to place hives in order to obtain propolis of excellent quality because the dominant life forms in that environment are shrubby species that produce resinous exudates with a high content of chalcones, flavones and flavonols. |
| format | info:ar-repo/semantics/artículo |
| id | INTA12346 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | Sage Publishing |
| publisherStr | Sage Publishing |
| record_format | dspace |
| spelling | INTA123462022-07-18T17:01:36Z Chalcones in Bioactive Argentine Propolis Collected in Arid Environments Solórzano, Eliana Vera, Nancy Roxana Cuello, Ana Soledad Ordóñez, Roxana Mabel Zampini, Iris Catiana Maldonado, Luis Maria Bedascarrasbure, Enrique Luciano Isla, María Inés Propóleos Calcona Medio Ambiente Zona Arida Argentina Propolis Chalcones Environment Arid Zones The aim of this study was to assess the chemical and biological profile of propolis samples collected in arid environments of north-western Argentina. The samples were from two phytogeographical regions (Prepuna and Monte de Catamarca Province). Propolis ethanolic extracts (PEE) and chloroform (CHL), hexane (HEX) and aqueous (AQ) sub-extracts of samples from three regions (CAT-I; CAT-II and CAT-III) were obtained. All PEE exhibited antioxidant activity in the DPPH radical scavenging assay (SC50 values between 28 and 43 μg DW/mL). The CHL extract was the most active (SC50 values between 10 and 37 μg DW/mL). The antioxidant activity in the β-carotene bleaching assays was more effective for PEE and CHL (IC50 values between 2 and 9 μg DW/mL, respectively). A similar pattern was observed for antibacterial activity. The highest inhibitory effect on the growth of human Gram-positive bacteria was observed for CHL-III and CHL-I (Monte region) with minimal inhibitory concentration values (MIC100) of 50 to 100 μg DW/mL. Nine compounds were identified by HPLC-PAD. Two of them (2′,4′-dihydroxychalcone and 2′,4′- dihydroxy 3′-methoxychalcone) were found only in propolis samples from the Monte phytogeographical region. We consider that the Argentine arid region is appropriate to place hives in order to obtain propolis of excellent quality because the dominant life forms in that environment are shrubby species that produce resinous exudates with a high content of chalcones, flavones and flavonols. EEA Famaillá Fil: Solórzano, Eliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Química del Noroeste; Argentina Fil: Vera, Nancy Roxana. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina Fil: Vera, Nancy Roxana. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Famaillá; Argentina Fil: Cuello, Ana Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste; Argentina Fil: Ordóñez, Roxana Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina. Fil: Ordóñez, Roxana Mabel. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo; Argentina. Fil: Ordóñez, Roxana Mabel. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina Fil: Zampini, Iris Catiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Química del Noroeste; Argentina Fil: Zampini, Iris Catiana. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo; Argentina Fil: Zampini, Iris Catiana. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina Fil: Maldonado, Luis Maria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Famaillá; Argentina Fil: Bedascarrasbure, Enrique Luciano. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Famaillá; Argentina Fil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina Fil: Isla, Maria Ines. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina Fil: Isla, Maria Ines. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo; Argentina 2022-07-18T16:54:53Z 2022-07-18T16:54:53Z 2012-07 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/12346 https://journals.sagepub.com/doi/abs/10.1177/1934578X1200700718 1934-578X 1555-9475 https://doi.org/10.1177/1934578X1200700718 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Argentina .......... (nation) (World, South America) 7006477 Sage Publishing Natural Product Communications 7 (7) : 879-882 (July 2012) |
| spellingShingle | Propóleos Calcona Medio Ambiente Zona Arida Argentina Propolis Chalcones Environment Arid Zones Solórzano, Eliana Vera, Nancy Roxana Cuello, Ana Soledad Ordóñez, Roxana Mabel Zampini, Iris Catiana Maldonado, Luis Maria Bedascarrasbure, Enrique Luciano Isla, María Inés Chalcones in Bioactive Argentine Propolis Collected in Arid Environments |
| title | Chalcones in Bioactive Argentine Propolis Collected in Arid Environments |
| title_full | Chalcones in Bioactive Argentine Propolis Collected in Arid Environments |
| title_fullStr | Chalcones in Bioactive Argentine Propolis Collected in Arid Environments |
| title_full_unstemmed | Chalcones in Bioactive Argentine Propolis Collected in Arid Environments |
| title_short | Chalcones in Bioactive Argentine Propolis Collected in Arid Environments |
| title_sort | chalcones in bioactive argentine propolis collected in arid environments |
| topic | Propóleos Calcona Medio Ambiente Zona Arida Argentina Propolis Chalcones Environment Arid Zones |
| url | http://hdl.handle.net/20.500.12123/12346 https://journals.sagepub.com/doi/abs/10.1177/1934578X1200700718 https://doi.org/10.1177/1934578X1200700718 |
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