Stress response and detoxification mechanisms involved in non-target-site herbicide resistance in sunflower

The nature of non-target-site herbicide resistance (NTSR) to imidazolinone (IMI) in HA425 sunflower (Helianthus annuus L.) has not yet been fully characterized but could be related to xenobiotic metabolism. The objective of this study was to evaluate the role of cytochrome P450 monooxygenases (P450s...

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Autores principales: Vega, Tatiana, Gil, Mercedes, Martin, Gabriela, Moschen, Sebastian Nicolas, Picardi, Liliana, Nestares, Graciela
Formato: Artículo
Lenguaje:Inglés
Publicado: Wiley 2022
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/11724
https://acsess.onlinelibrary.wiley.com/doi/abs/10.1002/csc2.20138
https://doi.org/10.1002/csc2.20138
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author Vega, Tatiana
Gil, Mercedes
Martin, Gabriela
Moschen, Sebastian Nicolas
Picardi, Liliana
Nestares, Graciela
author_browse Gil, Mercedes
Martin, Gabriela
Moschen, Sebastian Nicolas
Nestares, Graciela
Picardi, Liliana
Vega, Tatiana
author_facet Vega, Tatiana
Gil, Mercedes
Martin, Gabriela
Moschen, Sebastian Nicolas
Picardi, Liliana
Nestares, Graciela
author_sort Vega, Tatiana
collection INTA Digital
description The nature of non-target-site herbicide resistance (NTSR) to imidazolinone (IMI) in HA425 sunflower (Helianthus annuus L.) has not yet been fully characterized but could be related to xenobiotic metabolism. The objective of this study was to evaluate the role of cytochrome P450 monooxygenases (P450s) and other detoxification-related proteins in NTSR in sunflower. Two sunflower inbred lines were used: HA 425, which is IMI resistant (Imisun), and HA 89, which is IMI susceptible. The growth response to the IMI herbicide imazethapyr in combination with the P450 inhibitors 1-aminobenzotriazole (ABT) or piperonyl butoxide (PBO) was evaluated in 15-d-old sunflower plantlets. Roots were collected, and label-free quantitation (LFQ) proteomic analysis was carried out to characterize the NTSR mechanisms involved in the IMI resistance trait in sunflower. The increased phytotoxicity of imazethapyr observed in the resistant line when ABT or PBO were present agrees with the hypothesis that NTSR mechanisms may contribute to herbicide resistance in sunflower. The herbicide treatment also led to changes in the levels of biotic and abiotic stress-related proteins, glutathione S-transferases, and cytochrome P450s, among others. Plant growth and root protein expression response to IMI herbicides in sunflower would be a combination of stress-related and detoxification mechanisms. Understanding the basis of NTSR becomes helpful to exploit this trait in sunflower crop and to develop xenobiotic-resistant, soil-remediating cultivars.
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spelling INTA117242022-04-25T14:34:46Z Stress response and detoxification mechanisms involved in non-target-site herbicide resistance in sunflower Vega, Tatiana Gil, Mercedes Martin, Gabriela Moschen, Sebastian Nicolas Picardi, Liliana Nestares, Graciela Girasol Herbicidas Resistencia a los Herbicidas Estres Desintoxicación Helianthus annuus Sunflowers Herbicides Herbicide Resistance Stress Detoxification The nature of non-target-site herbicide resistance (NTSR) to imidazolinone (IMI) in HA425 sunflower (Helianthus annuus L.) has not yet been fully characterized but could be related to xenobiotic metabolism. The objective of this study was to evaluate the role of cytochrome P450 monooxygenases (P450s) and other detoxification-related proteins in NTSR in sunflower. Two sunflower inbred lines were used: HA 425, which is IMI resistant (Imisun), and HA 89, which is IMI susceptible. The growth response to the IMI herbicide imazethapyr in combination with the P450 inhibitors 1-aminobenzotriazole (ABT) or piperonyl butoxide (PBO) was evaluated in 15-d-old sunflower plantlets. Roots were collected, and label-free quantitation (LFQ) proteomic analysis was carried out to characterize the NTSR mechanisms involved in the IMI resistance trait in sunflower. The increased phytotoxicity of imazethapyr observed in the resistant line when ABT or PBO were present agrees with the hypothesis that NTSR mechanisms may contribute to herbicide resistance in sunflower. The herbicide treatment also led to changes in the levels of biotic and abiotic stress-related proteins, glutathione S-transferases, and cytochrome P450s, among others. Plant growth and root protein expression response to IMI herbicides in sunflower would be a combination of stress-related and detoxification mechanisms. Understanding the basis of NTSR becomes helpful to exploit this trait in sunflower crop and to develop xenobiotic-resistant, soil-remediating cultivars. EEA Famaillá Fil: Vega, Tatiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ciencias Agrarias; Argentina Fil: Vega, Tatiana. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Instituto de Investigaciones en Ciencias Agrarias; Argentina Fil: Gil, Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ciencias Agrarias; Argentina Fil: Gil, Mercedes. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Instituto de Investigaciones en Ciencias Agrarias; Argentina Fil: Martin, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ciencias Agrarias; Argentina Fil: Martin, Gabriela. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Instituto de Investigaciones en Ciencias Agrarias; Argentina Fil: Moschen, Sebastian Nicolás. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Famaillá; Argentina. Fil: Moschen, Sebastian Nicolás. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Picardi, Liliana. Universidad Nacional de Rosario. Consejo de Investigaciones; Argentina Fil: Nestares, Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ciencias Agrarias; Argentina Fil: Nestares, Graciela. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Instituto de Investigaciones en Ciencias Agrarias; Argentina 2022-04-25T14:29:49Z 2022-04-25T14:29:49Z 2020-08 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/11724 https://acsess.onlinelibrary.wiley.com/doi/abs/10.1002/csc2.20138 1435-0653 https://doi.org/10.1002/csc2.20138 eng info:eu-repo/semantics/restrictedAccess application/pdf Wiley Crop Science 60 (4) : 1809-1822 (July-August 2020)
spellingShingle Girasol
Herbicidas
Resistencia a los Herbicidas
Estres
Desintoxicación
Helianthus annuus
Sunflowers
Herbicides
Herbicide Resistance
Stress
Detoxification
Vega, Tatiana
Gil, Mercedes
Martin, Gabriela
Moschen, Sebastian Nicolas
Picardi, Liliana
Nestares, Graciela
Stress response and detoxification mechanisms involved in non-target-site herbicide resistance in sunflower
title Stress response and detoxification mechanisms involved in non-target-site herbicide resistance in sunflower
title_full Stress response and detoxification mechanisms involved in non-target-site herbicide resistance in sunflower
title_fullStr Stress response and detoxification mechanisms involved in non-target-site herbicide resistance in sunflower
title_full_unstemmed Stress response and detoxification mechanisms involved in non-target-site herbicide resistance in sunflower
title_short Stress response and detoxification mechanisms involved in non-target-site herbicide resistance in sunflower
title_sort stress response and detoxification mechanisms involved in non target site herbicide resistance in sunflower
topic Girasol
Herbicidas
Resistencia a los Herbicidas
Estres
Desintoxicación
Helianthus annuus
Sunflowers
Herbicides
Herbicide Resistance
Stress
Detoxification
url http://hdl.handle.net/20.500.12123/11724
https://acsess.onlinelibrary.wiley.com/doi/abs/10.1002/csc2.20138
https://doi.org/10.1002/csc2.20138
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