Efficient edition of the bovine PRNP prion gene in somatic cells and IVF embryos using the CRISPR/Cas9 system

The recently developed engineered nucleases, such as zinc-finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated nuclease (Cas) 9, provide new opportunities for gene editing in a straightforward manne...

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Bibliographic Details

Main Authors:	Bevacqua, Romina Jimena, Fernandez-Martín, R., Savy, Virginia, Canel, Natalia Gabriela, Gismondi, Maria Ines, Kues, Wilfried A., Carlson, Daniel F., Fahrenkrug, S.C., Niemann, H., Taboga, Oscar Alberto, Ferraris, Sergio, Salamone, Daniel Felipe
Format:	info:ar-repo/semantics/artículo
Language:	Inglés
Published:	2017
Subjects:	Genética Genetics Somatic Cells Cattle Spongiform Encephalopathy Células Somáticas Ganado Bovino Encefalopatía Espongiforme Mal de la Vaca Loca
Online Access:	http://hdl.handle.net/20.500.12123/1111 http://www.theriojournal.com/article/S0093-691X(16)30264-3/fulltext https://doi.org/10.1016/j.theriogenology.2016.06.010