Development of a construct-based risk assessment framework for genetic engineered crops

Experience gained in the risk assessment (RA) of genetically engineered (GE) crops since their first experimental introductions in the early nineties, has increased the level of familiarity with these breeding methodologies and has motivated several agencies and expert groups worldwide to revisit t...

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Main Authors: Becker, M.P., Boari, P., Burachik, Moisés, Cuadrado, V., Junco, Mariano, Lede, S., Lema, Martín, Lewi, Dalia Marcela, Maggi, Andrés, Meoniz,Ignacio Alberto, Noe, G., Roca, Cecilia, Robredo, Claudio Gabriel, Rubinstein, Clara, Vicien, Carmen, Whelan, Agustina
Format: Artículo
Language:Inglés
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/20.500.12123/1103
https://link.springer.com/article/10.1007%2Fs11248-016-9955-3
https://doi.org/10.1007/s11248-016-9955-3
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author Becker, M.P.
Boari, P.
Burachik, Moisés
Cuadrado, V.
Junco, Mariano
Lede, S.
Lema, Martín
Lewi, Dalia Marcela
Maggi, Andrés
Meoniz,Ignacio Alberto
Noe, G.
Roca, Cecilia
Robredo, Claudio Gabriel
Rubinstein, Clara
Vicien, Carmen
Whelan, Agustina
author_browse Becker, M.P.
Boari, P.
Burachik, Moisés
Cuadrado, V.
Junco, Mariano
Lede, S.
Lema, Martín
Lewi, Dalia Marcela
Maggi, Andrés
Meoniz,Ignacio Alberto
Noe, G.
Robredo, Claudio Gabriel
Roca, Cecilia
Rubinstein, Clara
Vicien, Carmen
Whelan, Agustina
author_facet Becker, M.P.
Boari, P.
Burachik, Moisés
Cuadrado, V.
Junco, Mariano
Lede, S.
Lema, Martín
Lewi, Dalia Marcela
Maggi, Andrés
Meoniz,Ignacio Alberto
Noe, G.
Roca, Cecilia
Robredo, Claudio Gabriel
Rubinstein, Clara
Vicien, Carmen
Whelan, Agustina
author_sort Becker, M.P.
collection INTA Digital
description Experience gained in the risk assessment (RA) of genetically engineered (GE) crops since their first experimental introductions in the early nineties, has increased the level of familiarity with these breeding methodologies and has motivated several agencies and expert groups worldwide to revisit the scientific criteria underlying the RA process. Along these lines, the need to engage in a scientific discussion for the case of GE crops transformed with similar constructs was recently identified in Argentina. In response to this need, the Argentine branch of the International Life Sciences Institute (ILSI Argentina) convened a tripartite working group to discuss a science-based evaluation approach for transformation events developed with genetic constructs which are identical or similar to those used in previously evaluated or approved GE crops. This discussion considered new transformation events within the same or different species and covered both environmental and food safety aspects. A construct similarity concept was defined, considering the biological function of the introduced genes. Factors like environmental and dietary exposure, familiarity with both the crop and the trait as well as the crop biology, were identified as key to inform a construct-based RA process.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
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spelling INTA11032017-12-29T15:33:48Z Development of a construct-based risk assessment framework for genetic engineered crops Becker, M.P. Boari, P. Burachik, Moisés Cuadrado, V. Junco, Mariano Lede, S. Lema, Martín Lewi, Dalia Marcela Maggi, Andrés Meoniz,Ignacio Alberto Noe, G. Roca, Cecilia Robredo, Claudio Gabriel Rubinstein, Clara Vicien, Carmen Whelan, Agustina Genética Evaluación de Riesgos Ingeniería Genética Genetics Risk Assessment Genetic Engineering Experience gained in the risk assessment (RA) of genetically engineered (GE) crops since their first experimental introductions in the early nineties, has increased the level of familiarity with these breeding methodologies and has motivated several agencies and expert groups worldwide to revisit the scientific criteria underlying the RA process. Along these lines, the need to engage in a scientific discussion for the case of GE crops transformed with similar constructs was recently identified in Argentina. In response to this need, the Argentine branch of the International Life Sciences Institute (ILSI Argentina) convened a tripartite working group to discuss a science-based evaluation approach for transformation events developed with genetic constructs which are identical or similar to those used in previously evaluated or approved GE crops. This discussion considered new transformation events within the same or different species and covered both environmental and food safety aspects. A construct similarity concept was defined, considering the biological function of the introduced genes. Factors like environmental and dietary exposure, familiarity with both the crop and the trait as well as the crop biology, were identified as key to inform a construct-based RA process. Inst. de Genética "Ewald A. Favret"- IGEAF Fil: Becker, M.P. Bayer SA,; Argentina Fil: Boari, P. Ministerio de Agroindustria. Secretaría de Valor Agregado. Dirección de Biotecnología; Argentina Fil: Burachik, Moisés. Instituto de Agrobiotecnologia Rosario; Argentina Fil: Cuadrado, V. Monsanto Argentina; Argentina Fil: Junco, Mariano. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Coordinación de Biotecnología y Productos Industrializados; Argentina Fil: Lede, S. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Lema, Martín. Ministerio de Agroindustria. Secretaría de Valor Agregado. Dirección de Biotecnología; Argentina Fil: Lewi, Dalia Marcela. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética "Ewald A. Favret"; Argentina Fil: Maggi, Andrés. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Dirección de Calidad Agroalimentaria; Argentina Fil: Meoniz, Ignacio Alberto. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Análisis de Riesgo de Organismos Genéricamente Modificados; Argentina Fil: Noe, G. Syngenta Agro; Argentina Fil: Roca, Cecilia. Dow Agroscience SA; Argentina Fil: Robredo, Claudio Gabriel. Chacra Experimental Agrícola Santa Rosa; Argentina Fil: Rubinstein, Clara. Monsanto Argentina; Argantina. Instituto Internacional de Ciencias de la Vida; Argentina Fil: Vicien, Carmen. Universidad de Buenos Aires; Argentina. Cámara de Exportadores de la República Argentina; Argentina Fil: Whelan, Agustina. Ministerio de Agroindustria. Secretaría de Valor Agregado. Dirección de Biotecnología; Argentina 2017-09-01T14:19:59Z 2017-09-01T14:19:59Z 2016 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion info:ar-repo/semantics/artículo http://hdl.handle.net/20.500.12123/1103 https://link.springer.com/article/10.1007%2Fs11248-016-9955-3 0962-8819 (Print) 1573-9368 (Online) https://doi.org/10.1007/s11248-016-9955-3 eng info:eu-repo/semantics/restrictedAccess application/pdf Transgenic research 25 (5) : 597–607. (October 2016)
spellingShingle Genética
Evaluación de Riesgos
Ingeniería Genética
Genetics
Risk Assessment
Genetic Engineering
Becker, M.P.
Boari, P.
Burachik, Moisés
Cuadrado, V.
Junco, Mariano
Lede, S.
Lema, Martín
Lewi, Dalia Marcela
Maggi, Andrés
Meoniz,Ignacio Alberto
Noe, G.
Roca, Cecilia
Robredo, Claudio Gabriel
Rubinstein, Clara
Vicien, Carmen
Whelan, Agustina
Development of a construct-based risk assessment framework for genetic engineered crops
title Development of a construct-based risk assessment framework for genetic engineered crops
title_full Development of a construct-based risk assessment framework for genetic engineered crops
title_fullStr Development of a construct-based risk assessment framework for genetic engineered crops
title_full_unstemmed Development of a construct-based risk assessment framework for genetic engineered crops
title_short Development of a construct-based risk assessment framework for genetic engineered crops
title_sort development of a construct based risk assessment framework for genetic engineered crops
topic Genética
Evaluación de Riesgos
Ingeniería Genética
Genetics
Risk Assessment
Genetic Engineering
url http://hdl.handle.net/20.500.12123/1103
https://link.springer.com/article/10.1007%2Fs11248-016-9955-3
https://doi.org/10.1007/s11248-016-9955-3
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