Molecular characterization and antimicrobial resistance profiles of Salmonella Heidelberg isolates from poultry

In the last 10 years, Salmonella Heidelberg has been extensively isolated from poultry in several countries. In this context, molecular characterization is essential to understand whether the strains have entered the farms from a single or several sources. Thus, the aim of this study was to determin...

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Autores principales: Dominguez, Johanna Elizabeth, Viñas, María Rosa, Herrera, Mariana, Moroni, Mirian, Gutkind, Gabriel Omar, Mercado, Elsa Cristina, Di Conza, José Alejandro, Chacana, Pablo
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: Wiley 2021
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/10883
https://onlinelibrary.wiley.com/doi/10.1111/zph.12819
https://doi.org/10.1111/zph.12819
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author Dominguez, Johanna Elizabeth
Viñas, María Rosa
Herrera, Mariana
Moroni, Mirian
Gutkind, Gabriel Omar
Mercado, Elsa Cristina
Di Conza, José Alejandro
Chacana, Pablo
author_browse Chacana, Pablo
Di Conza, José Alejandro
Dominguez, Johanna Elizabeth
Gutkind, Gabriel Omar
Herrera, Mariana
Mercado, Elsa Cristina
Moroni, Mirian
Viñas, María Rosa
author_facet Dominguez, Johanna Elizabeth
Viñas, María Rosa
Herrera, Mariana
Moroni, Mirian
Gutkind, Gabriel Omar
Mercado, Elsa Cristina
Di Conza, José Alejandro
Chacana, Pablo
author_sort Dominguez, Johanna Elizabeth
collection INTA Digital
description In the last 10 years, Salmonella Heidelberg has been extensively isolated from poultry in several countries. In this context, molecular characterization is essential to understand whether the strains have entered the farms from a single or several sources. Thus, the aim of this study was to determine the genetic relationship and antimicrobial susceptibility of S. Heidelberg strains isolated between 2011 and 2012 from broiler farms belonging to three integrated poultry companies located in Argentina. The genetic relatedness of the S. Heidelberg isolates was determined by pulsed-field gel electrophoresis (PFGE), and resistance to 21 antimicrobials was determined by the disc diffusion method. The isolates were assigned to four PFGE patterns. Most of the strains showed 100% similarity and belonged to the same integrated poultry company. This PFGE pattern was also prevalent in S. Heidelberg strains isolated from humans in several provinces of Argentina, which suggests an epidemiological association between human and poultry strains. All the isolates were classified as multidrug-resistant (MDR), and no clear relationship was observed between PFGE and resistance patterns. S. Heidelberg strains may circulate among farms from the same integrated company due to common sources of contamination. To guarantee the safety of the poultry product for the consumers, holistic approaches including surveillance of Salmonella throughout the production chain together with control measures are crucial.
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spelling INTA108832021-12-10T14:21:47Z Molecular characterization and antimicrobial resistance profiles of Salmonella Heidelberg isolates from poultry Dominguez, Johanna Elizabeth Viñas, María Rosa Herrera, Mariana Moroni, Mirian Gutkind, Gabriel Omar Mercado, Elsa Cristina Di Conza, José Alejandro Chacana, Pablo Aves de Corral Salmonella Genética Molecular Resistencia a los Antimicrobianos Poultry Molecular Genetics Antimicrobial Resistance In the last 10 years, Salmonella Heidelberg has been extensively isolated from poultry in several countries. In this context, molecular characterization is essential to understand whether the strains have entered the farms from a single or several sources. Thus, the aim of this study was to determine the genetic relationship and antimicrobial susceptibility of S. Heidelberg strains isolated between 2011 and 2012 from broiler farms belonging to three integrated poultry companies located in Argentina. The genetic relatedness of the S. Heidelberg isolates was determined by pulsed-field gel electrophoresis (PFGE), and resistance to 21 antimicrobials was determined by the disc diffusion method. The isolates were assigned to four PFGE patterns. Most of the strains showed 100% similarity and belonged to the same integrated poultry company. This PFGE pattern was also prevalent in S. Heidelberg strains isolated from humans in several provinces of Argentina, which suggests an epidemiological association between human and poultry strains. All the isolates were classified as multidrug-resistant (MDR), and no clear relationship was observed between PFGE and resistance patterns. S. Heidelberg strains may circulate among farms from the same integrated company due to common sources of contamination. To guarantee the safety of the poultry product for the consumers, holistic approaches including surveillance of Salmonella throughout the production chain together with control measures are crucial. Instituto de Patobiología Fil: Dominguez, Johana Elizabeth. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Fil: Dominguez, Johana Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Viñas, María Rosa. Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán (ANLIS-Malbrán). Servicios de Enterobacterias; Argentina Fil: Herrera, Mariana. Servicio Nacional de Sanidad y Calidad Agroalimentaria (SENASA). Dirección General de Laboratorios y Control Técnico; Argentina Fil: Moroni, Mirian. Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán (ANLIS-Malbrán). Servicios de Enterobacterias; Argentina Fil: Gutkind, Gabriel O. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Investigaciones en Bacteriología y Virología Molecular; Argentina Fil: Gutkind, Gabriel O. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Mercado, Elsa Cristina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina Fil: Di Conza, José A. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Investigaciones en Bacteriología y Virología Molecular; Argentina Fil: Di Conza, José A. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Chacana, Pablo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina Fil: Chacana, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina 2021-12-10T14:17:42Z 2021-12-10T14:17:42Z 2021-02 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/10883 https://onlinelibrary.wiley.com/doi/10.1111/zph.12819 1863-2378 https://doi.org/10.1111/zph.12819 eng info:eu-repo/semantics/restrictedAccess application/pdf Wiley Zoonoses and Public Health 68 (4) : 309-315 (June 2021)
spellingShingle Aves de Corral
Salmonella
Genética Molecular
Resistencia a los Antimicrobianos
Poultry
Molecular Genetics
Antimicrobial Resistance
Dominguez, Johanna Elizabeth
Viñas, María Rosa
Herrera, Mariana
Moroni, Mirian
Gutkind, Gabriel Omar
Mercado, Elsa Cristina
Di Conza, José Alejandro
Chacana, Pablo
Molecular characterization and antimicrobial resistance profiles of Salmonella Heidelberg isolates from poultry
title Molecular characterization and antimicrobial resistance profiles of Salmonella Heidelberg isolates from poultry
title_full Molecular characterization and antimicrobial resistance profiles of Salmonella Heidelberg isolates from poultry
title_fullStr Molecular characterization and antimicrobial resistance profiles of Salmonella Heidelberg isolates from poultry
title_full_unstemmed Molecular characterization and antimicrobial resistance profiles of Salmonella Heidelberg isolates from poultry
title_short Molecular characterization and antimicrobial resistance profiles of Salmonella Heidelberg isolates from poultry
title_sort molecular characterization and antimicrobial resistance profiles of salmonella heidelberg isolates from poultry
topic Aves de Corral
Salmonella
Genética Molecular
Resistencia a los Antimicrobianos
Poultry
Molecular Genetics
Antimicrobial Resistance
url http://hdl.handle.net/20.500.12123/10883
https://onlinelibrary.wiley.com/doi/10.1111/zph.12819
https://doi.org/10.1111/zph.12819
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