Bioprospecting of microbial strains for biofuel production: metabolic engineering, applications, and challenges
The issues of global warming, coupled with fossil fuel depletion, have undoubtedly led to renewed interest in other sources of commercial fuels. The search for renewable fuels has motivated research into the biological degradation of lignocellulosic biomass feedstock to produce biofuels such as bioe...
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| Format: | Artículo |
| Language: | Inglés |
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BMC
2021
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| Online Access: | http://hdl.handle.net/20.500.12123/10746 https://biotechnologyforbiofuels.biomedcentral.com/articles/10.1186/s13068-020-01853-2 https://doi.org/10.1186/s13068-020-01853-2 |
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| author | Adegboye, Mobolaji Felicia Ojuederie, Omena Bernard Talia, Paola Mónica Babalola, Olubukola Oluranti |
| author_browse | Adegboye, Mobolaji Felicia Babalola, Olubukola Oluranti Ojuederie, Omena Bernard Talia, Paola Mónica |
| author_facet | Adegboye, Mobolaji Felicia Ojuederie, Omena Bernard Talia, Paola Mónica Babalola, Olubukola Oluranti |
| author_sort | Adegboye, Mobolaji Felicia |
| collection | INTA Digital |
| description | The issues of global warming, coupled with fossil fuel depletion, have undoubtedly led to renewed interest in other sources of commercial fuels. The search for renewable fuels has motivated research into the biological degradation of lignocellulosic biomass feedstock to produce biofuels such as bioethanol, biodiesel, and biohydrogen. The model strain for biofuel production needs the capability to utilize a high amount of substrate, transportation of sugar through fast and deregulated pathways, ability to tolerate inhibitory compounds and end products, and increased metabolic fluxes to produce an improved fermentation product. Engineering microbes might be a great approach to produce biofuel from lignocellulosic biomass by exploiting metabolic pathways economically. Metabolic engineering is an advanced technology for the construction of highly effective microbial cell factories and a key component for the next-generation bioeconomy. It has been extensively used to redirect the biosynthetic pathway to produce desired products in several native or engineered hosts. A wide range of novel compounds has been manufactured through engineering metabolic pathways or endogenous metabolism optimizations by metabolic engineers. This review is focused on the potential utilization of engineered strains to produce biofuel and gives prospects for improvement in metabolic engineering for new strain development using advanced technologies. |
| format | Artículo |
| id | INTA10746 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | BMC |
| publisherStr | BMC |
| record_format | dspace |
| spelling | INTA107462021-11-11T11:45:21Z Bioprospecting of microbial strains for biofuel production: metabolic engineering, applications, and challenges Adegboye, Mobolaji Felicia Ojuederie, Omena Bernard Talia, Paola Mónica Babalola, Olubukola Oluranti Biocarburante Lignocelulosa Producción Biofuels Lignocellulose Production Biocombustibles The issues of global warming, coupled with fossil fuel depletion, have undoubtedly led to renewed interest in other sources of commercial fuels. The search for renewable fuels has motivated research into the biological degradation of lignocellulosic biomass feedstock to produce biofuels such as bioethanol, biodiesel, and biohydrogen. The model strain for biofuel production needs the capability to utilize a high amount of substrate, transportation of sugar through fast and deregulated pathways, ability to tolerate inhibitory compounds and end products, and increased metabolic fluxes to produce an improved fermentation product. Engineering microbes might be a great approach to produce biofuel from lignocellulosic biomass by exploiting metabolic pathways economically. Metabolic engineering is an advanced technology for the construction of highly effective microbial cell factories and a key component for the next-generation bioeconomy. It has been extensively used to redirect the biosynthetic pathway to produce desired products in several native or engineered hosts. A wide range of novel compounds has been manufactured through engineering metabolic pathways or endogenous metabolism optimizations by metabolic engineers. This review is focused on the potential utilization of engineered strains to produce biofuel and gives prospects for improvement in metabolic engineering for new strain development using advanced technologies. Instituto de Biotecnología Fil: Adegboye, Mobolaji Felicia. North-West University. Faculty of Natural and Agricultural Sciences. Food Security and Safety Niche Area; Sudáfrica Fil: Ojuederie, Omena Bernard. North-West University. Faculty of Natural and Agricultural Sciences. Food Security and Safety Niche Area; Sudáfrica Fil: Ojuederie, Omena Bernard. Kings University. Faculty of Science. Department of Biological Sciences; Nigeria Fil: Talia, Paola Mónica. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular (IABIMO); Argentina Fil: Talia, Paola Mónica. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Babalola, Olubukola Oluranti. North-West University. Faculty of Natural and Agricultural Sciences. Food Security and Safety Niche Area; Sudáfrica 2021-11-11T11:42:46Z 2021-11-11T11:42:46Z 2021-01 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/10746 https://biotechnologyforbiofuels.biomedcentral.com/articles/10.1186/s13068-020-01853-2 1754-6834 https://doi.org/10.1186/s13068-020-01853-2 eng info:eu-repograntAgreement/INTA/PNAIyAV-1130034/AR./Desarrollo de procesos para la transformación de biomasa en bioenergía. info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf BMC Biotechnology for Biofuels 14 : Article number: 5 (06 January 2021) |
| spellingShingle | Biocarburante Lignocelulosa Producción Biofuels Lignocellulose Production Biocombustibles Adegboye, Mobolaji Felicia Ojuederie, Omena Bernard Talia, Paola Mónica Babalola, Olubukola Oluranti Bioprospecting of microbial strains for biofuel production: metabolic engineering, applications, and challenges |
| title | Bioprospecting of microbial strains for biofuel production: metabolic engineering, applications, and challenges |
| title_full | Bioprospecting of microbial strains for biofuel production: metabolic engineering, applications, and challenges |
| title_fullStr | Bioprospecting of microbial strains for biofuel production: metabolic engineering, applications, and challenges |
| title_full_unstemmed | Bioprospecting of microbial strains for biofuel production: metabolic engineering, applications, and challenges |
| title_short | Bioprospecting of microbial strains for biofuel production: metabolic engineering, applications, and challenges |
| title_sort | bioprospecting of microbial strains for biofuel production metabolic engineering applications and challenges |
| topic | Biocarburante Lignocelulosa Producción Biofuels Lignocellulose Production Biocombustibles |
| url | http://hdl.handle.net/20.500.12123/10746 https://biotechnologyforbiofuels.biomedcentral.com/articles/10.1186/s13068-020-01853-2 https://doi.org/10.1186/s13068-020-01853-2 |
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