Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae)
Genotoxic effects of Cd?2, Cr?6, and Cu?2 on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genot...
| Autores principales: | , , , , |
|---|---|
| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
| Publicado: |
2017
|
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/1041 https://link.springer.com/article/10.1007%2Fs00128-016-1774-y https://doi.org/10.1007/s00128-016-1774-y |
| _version_ | 1855034728695988224 |
|---|---|
| author | Gasulla, Javier Carriquiriborde, Pedro Picco, Sebastian Julio Ronco, Alicia Estela de Luca, Julio Cesar |
| author_browse | Carriquiriborde, Pedro Gasulla, Javier Picco, Sebastian Julio Ronco, Alicia Estela de Luca, Julio Cesar |
| author_facet | Gasulla, Javier Carriquiriborde, Pedro Picco, Sebastian Julio Ronco, Alicia Estela de Luca, Julio Cesar |
| author_sort | Gasulla, Javier |
| collection | INTA Digital |
| description | Genotoxic effects of Cd?2, Cr?6, and Cu?2 on the gill and liver of the Argentinean Silverside (Odontesthes
bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were
exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was
only observed in the gill of fish exposed to Cr?6 and Cu?2,
and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd?2 by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd?2 and Cr?6 and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant
concentrations and the gill was the most sensitive organ. |
| format | info:ar-repo/semantics/artículo |
| id | INTA1041 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| record_format | dspace |
| spelling | INTA10412019-07-18T11:52:28Z Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae) Gasulla, Javier Carriquiriborde, Pedro Picco, Sebastian Julio Ronco, Alicia Estela de Luca, Julio Cesar Genotoxicity Fishes Genotoxicidad Odontesthes bonariensis Peces Genotoxic effects of Cd?2, Cr?6, and Cu?2 on the gill and liver of the Argentinean Silverside (Odontesthes bonariensis) were studied using the comet assay and in relation with the metal tissue accumulation. Fish were exposed to three waterborne concentrations of each metal for 2 and 16 days. Genotoxicity was assessed by the single cell gel electrophoresis (comet assay). After 2 days, significant increase of the genetic damage index (GDI) was only observed in the gill of fish exposed to Cr?6 and Cu?2, and the LOECs were 2160 nM and 921.1 nM, respectively. The gill LOEC for Cd?2 by 16 days was 9.4 nM. In the liver, LOECs were obtained only for Cd?2 and Cr?6 and were 9.4 and 2160 nM, respectively. The three metals were able to induce genotoxic effects at environmentally relevant concentrations and the gill was the most sensitive organ. Inst. de Microbiología y Zoología Agrícola IMyZA Fil: Gasulla, Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Microbiología y Zoología Agrícola; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; Argentina Fil: Picco, Sebastian Julio. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - la Plata. Instituto de Genetica Veterinaria Ing Fernando Noel Dulout; Universidad Nacional de la Plata. Facultad de Cs.veterinarias. Departamento de Cs.basicas. Laboratorio de Nutricion Mineral y Fisiologia Reproductiva; Argentina Fil: Carriquiriborde, Pedro. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Departamento de Química. Centro de Investigaciones del Medio Ambiente; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Cientifico Tecnológico La Plata; Argentina Fil: Ronco, Alicia Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmosfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmosfera; Argentina Fil: de Luca, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Genética Veterinaria "Ingeniero Fernando Noel Dulout"; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina 2017-08-25T12:51:27Z 2017-08-25T12:51:27Z 2016 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion http://hdl.handle.net/20.500.12123/1041 https://link.springer.com/article/10.1007%2Fs00128-016-1774-y 0007-4861 (Print) 1432-0800 (Online) https://doi.org/10.1007/s00128-016-1774-y eng info:eu-repo/semantics/restrictedAccess application/pdf Bulletin of environmental contamination and toxicology 96 (5) : 591–595. (May 2016) |
| spellingShingle | Genotoxicity Fishes Genotoxicidad Odontesthes bonariensis Peces Gasulla, Javier Carriquiriborde, Pedro Picco, Sebastian Julio Ronco, Alicia Estela de Luca, Julio Cesar Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae) |
| title | Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae) |
| title_full | Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae) |
| title_fullStr | Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae) |
| title_full_unstemmed | Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae) |
| title_short | Genotoxic effects induced by Cd+2, Cr+6, Cu+2 in the Gill and Liver of Odontesthes bonariensis (Piscies, Atherinopsidae) |
| title_sort | genotoxic effects induced by cd 2 cr 6 cu 2 in the gill and liver of odontesthes bonariensis piscies atherinopsidae |
| topic | Genotoxicity Fishes Genotoxicidad Odontesthes bonariensis Peces |
| url | http://hdl.handle.net/20.500.12123/1041 https://link.springer.com/article/10.1007%2Fs00128-016-1774-y https://doi.org/10.1007/s00128-016-1774-y |
| work_keys_str_mv | AT gasullajavier genotoxiceffectsinducedbycd2cr6cu2inthegillandliverofodontesthesbonariensispisciesatherinopsidae AT carriquiribordepedro genotoxiceffectsinducedbycd2cr6cu2inthegillandliverofodontesthesbonariensispisciesatherinopsidae AT piccosebastianjulio genotoxiceffectsinducedbycd2cr6cu2inthegillandliverofodontesthesbonariensispisciesatherinopsidae AT roncoaliciaestela genotoxiceffectsinducedbycd2cr6cu2inthegillandliverofodontesthesbonariensispisciesatherinopsidae AT delucajuliocesar genotoxiceffectsinducedbycd2cr6cu2inthegillandliverofodontesthesbonariensispisciesatherinopsidae |