The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato

Sucrose metabolism is important for most plants, both as the main source of carbon and via signaling mechanisms that have been proposed for this molecule. A cleaving enzyme, invertase (INV) channels sucrose into sink metabolism. Although acid soluble and insoluble invertases have been largely invest...

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Autores principales: Coluccio Leskow, Carla, Conte, Mariana, del Pozo, Talía, Bermudez Salazar, Luisa, Lira, Bruno Silvestre, Gramegna, Giovanna, Baroli, Irene, Burgos, Estanislao, Zavallo, Diego, Kamenetzky, Laura, Asis, Ramón, Gonzalez, Maurıcio, Fernie, Alisdair R., Rossi, Magdalena, Osorio, Sonia, Carrari, Fernando
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/10145
https://academic.oup.com/jxb/article-abstract/72/7/2525/6047586
https://doi.org/10.1093/jxb/eraa594
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author Coluccio Leskow, Carla
Conte, Mariana
del Pozo, Talía
Bermudez Salazar, Luisa
Lira, Bruno Silvestre
Gramegna, Giovanna
Baroli, Irene
Burgos, Estanislao
Zavallo, Diego
Kamenetzky, Laura
Asis, Ramón
Gonzalez, Maurıcio
Fernie, Alisdair R.
Rossi, Magdalena
Osorio, Sonia
Carrari, Fernando
author_browse Asis, Ramón
Baroli, Irene
Bermudez Salazar, Luisa
Burgos, Estanislao
Carrari, Fernando
Coluccio Leskow, Carla
Conte, Mariana
Fernie, Alisdair R.
Gonzalez, Maurıcio
Gramegna, Giovanna
Kamenetzky, Laura
Lira, Bruno Silvestre
Osorio, Sonia
Rossi, Magdalena
Zavallo, Diego
del Pozo, Talía
author_facet Coluccio Leskow, Carla
Conte, Mariana
del Pozo, Talía
Bermudez Salazar, Luisa
Lira, Bruno Silvestre
Gramegna, Giovanna
Baroli, Irene
Burgos, Estanislao
Zavallo, Diego
Kamenetzky, Laura
Asis, Ramón
Gonzalez, Maurıcio
Fernie, Alisdair R.
Rossi, Magdalena
Osorio, Sonia
Carrari, Fernando
author_sort Coluccio Leskow, Carla
collection INTA Digital
description Sucrose metabolism is important for most plants, both as the main source of carbon and via signaling mechanisms that have been proposed for this molecule. A cleaving enzyme, invertase (INV) channels sucrose into sink metabolism. Although acid soluble and insoluble invertases have been largely investigated, studies on the role of neutral invertases (A/N-INV) have lagged behind. Here, we identified a tomato A/N-INV encoding gene (NI6) co-localizing with a previously reported quantitative trait locus (QTL) largely affecting primary carbon metabolism in tomato. Of the eight A/N-INV genes identified in the tomato genome, NI6 mRNA is present in all organs, but its expression was higher in sink tissues (mainly roots and fruits). A NI6-GFP fusion protein localized to the cytosol of mesophyll cells. Tomato NI6-silenced plants showed impaired growth phenotype, delayed flowering and a dramatic reduction in fruit set. Global gene expression and metabolite profile analyses of these plants revealed that NI6 is not only essential for sugar metabolism, but also plays a signaling role in stress adaptation. We also identified major hubs, whose expression patterns were greatly affected by NI6 silencing; these hubs were within the signaling cascade that coordinates carbohydrate metabolism with growth and development in tomato.
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publishDateRange 2021
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spelling INTA101452021-08-31T11:08:06Z The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato Coluccio Leskow, Carla Conte, Mariana del Pozo, Talía Bermudez Salazar, Luisa Lira, Bruno Silvestre Gramegna, Giovanna Baroli, Irene Burgos, Estanislao Zavallo, Diego Kamenetzky, Laura Asis, Ramón Gonzalez, Maurıcio Fernie, Alisdair R. Rossi, Magdalena Osorio, Sonia Carrari, Fernando Solanum lycopersicum Tomate Silenciamiento Genético Crecimiento Floración Fructificación Rendimiento Fructofuranosidasa Metabolismo Carbono Tomatoes Gene Silencing Growth Flowering Fruiting Yields Fructofuranosidase Metabolism Carbon Sucrose metabolism is important for most plants, both as the main source of carbon and via signaling mechanisms that have been proposed for this molecule. A cleaving enzyme, invertase (INV) channels sucrose into sink metabolism. Although acid soluble and insoluble invertases have been largely investigated, studies on the role of neutral invertases (A/N-INV) have lagged behind. Here, we identified a tomato A/N-INV encoding gene (NI6) co-localizing with a previously reported quantitative trait locus (QTL) largely affecting primary carbon metabolism in tomato. Of the eight A/N-INV genes identified in the tomato genome, NI6 mRNA is present in all organs, but its expression was higher in sink tissues (mainly roots and fruits). A NI6-GFP fusion protein localized to the cytosol of mesophyll cells. Tomato NI6-silenced plants showed impaired growth phenotype, delayed flowering and a dramatic reduction in fruit set. Global gene expression and metabolite profile analyses of these plants revealed that NI6 is not only essential for sugar metabolism, but also plays a signaling role in stress adaptation. We also identified major hubs, whose expression patterns were greatly affected by NI6 silencing; these hubs were within the signaling cascade that coordinates carbohydrate metabolism with growth and development in tomato. Instituto de Biotecnología Fil: Coluccio Leskow, Carla. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina Fil: Coluccio Leskow, Carla. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Conte, Mariana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina Fil: Conte, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: del Pozo, Talía. Universidad Mayor. Centro Tecnológico de Recursos Vegetales. Escuela de Agronomía; Chile Fil: Bermudez Salazar, Luisa. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina Fil: Bermudez Salazar, Luisa. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Bermudez Salazar, Luisa. Universidad de Buenos Aires. Facultad de Agronomía. Cátedra de Genética; Argentina Fil: Lira, Bruno Silvestre. Universidade de São Pablo. Departamento de Botânica. Instituto de Biociencias; Brasil Fil: Gramegna, Giovanna. Universidade de São Pablo. Departamento de Botânica. Instituto de Biociencias; Brasil Fil: Baroli, Irene. Instituto de Biodiversidad y Biología Experimental Aplicada (IBBEA); Argentina Fil: Baroli, Irene. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Burgos, Estanislao. Universidad de Buenos Aires. Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE); Argentina Fil: Burgos, Estanislao. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Zavallo, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina Fil: Zavallo, Diego. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Kamenetzky, Laura. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Fisiología y Biología Molecular y Celular. Laboratorio de Genómica y Bioinformática de Patógenos; Argentina Fil: Asis, Ramón. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina Fil: Gonzalez, Maurıcio. Universidad Mayor. Centro Tecnológico de Recursos Vegetales. Escuela de Agronomía; Chile Fil: Fernie, Alisdair R. Max Planck Institute of Molecular Plant Physiology; Alemania Fil: Rossi, Magdalena. Universidade de São Pablo. Departamento de Botânica. Instituto de Biociencias; Brasil Fil: Osorio, Sonia. University of Malaga. Instituto de Hortofruticultura Subtropical y Mediterránea “La Mayora". Department of Molecular Biology and Biochemistry; España Fil: Osorio, Sonia. Consejo Superior de Investigaciones Científicas; España Fil: Carrari, Fernando. Universidad de Buenos Aires. Facultad de Agronomía. Cátedra de Genética; Argentina Fil: Carrari, Fernando. Universidad de Buenos Aires. Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE); Argentina 2021-08-31T10:55:21Z 2021-08-31T10:55:21Z 2021-03 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/10145 https://academic.oup.com/jxb/article-abstract/72/7/2525/6047586 1460-2431 https://doi.org/10.1093/jxb/eraa594 eng info:eu-repo/semantics/restrictedAccess application/pdf Oxford University Press Journal of Experimental Botany 72 (7) : 2525-2543 (Marzo 2021)
spellingShingle Solanum lycopersicum
Tomate
Silenciamiento Genético
Crecimiento
Floración
Fructificación
Rendimiento
Fructofuranosidasa
Metabolismo
Carbono
Tomatoes
Gene Silencing
Growth
Flowering
Fruiting
Yields
Fructofuranosidase
Metabolism
Carbon
Coluccio Leskow, Carla
Conte, Mariana
del Pozo, Talía
Bermudez Salazar, Luisa
Lira, Bruno Silvestre
Gramegna, Giovanna
Baroli, Irene
Burgos, Estanislao
Zavallo, Diego
Kamenetzky, Laura
Asis, Ramón
Gonzalez, Maurıcio
Fernie, Alisdair R.
Rossi, Magdalena
Osorio, Sonia
Carrari, Fernando
The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato
title The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato
title_full The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato
title_fullStr The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato
title_full_unstemmed The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato
title_short The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato
title_sort cytosolic invertase ni6 affects vegetative growth flowering fruit set and yield in tomato
topic Solanum lycopersicum
Tomate
Silenciamiento Genético
Crecimiento
Floración
Fructificación
Rendimiento
Fructofuranosidasa
Metabolismo
Carbono
Tomatoes
Gene Silencing
Growth
Flowering
Fruiting
Yields
Fructofuranosidase
Metabolism
Carbon
url http://hdl.handle.net/20.500.12123/10145
https://academic.oup.com/jxb/article-abstract/72/7/2525/6047586
https://doi.org/10.1093/jxb/eraa594
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