Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce clearance of EAV carrier state in stallions.
| Main Authors: | , , , , , , , , |
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| Format: | Artículo |
| Language: | Inglés |
| Published: |
2017
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/1009 http://www.j-evs.com/article/S0737-0806(16)00154-4/pdf http://dx.doi.org/10.1016/j.jevs.2016.02.123 |
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| author | Aduriz Guerrero, Matías Carossino, Mariano Go, Y.Y. Vincke, Cécile Balasuriya, Udeni B.R. Muyldermans, S. Wigdorovitz, Andres Barrandeguy, Maria Edith Parreño, Viviana |
| author_browse | Aduriz Guerrero, Matías Balasuriya, Udeni B.R. Barrandeguy, Maria Edith Carossino, Mariano Go, Y.Y. Muyldermans, S. Parreño, Viviana Vincke, Cécile Wigdorovitz, Andres |
| author_facet | Aduriz Guerrero, Matías Carossino, Mariano Go, Y.Y. Vincke, Cécile Balasuriya, Udeni B.R. Muyldermans, S. Wigdorovitz, Andres Barrandeguy, Maria Edith Parreño, Viviana |
| author_sort | Aduriz Guerrero, Matías |
| collection | INTA Digital |
| description | In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated.
This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce clearance of EAV carrier state in stallions. |
| format | Artículo |
| id | INTA1009 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| record_format | dspace |
| spelling | INTA10092019-06-05T17:00:47Z Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions Aduriz Guerrero, Matías Carossino, Mariano Go, Y.Y. Vincke, Cécile Balasuriya, Udeni B.R. Muyldermans, S. Wigdorovitz, Andres Barrandeguy, Maria Edith Parreño, Viviana Animal Diseases Stallions Nanotechnology Equine Arteritis Virus Enfermedades de los Animales Caballos Sementales Nanotecnología Virus de la Arteritis Equina In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce clearance of EAV carrier state in stallions. Inst.de Virología Fil: Aduriz Guerrero, Matías. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Carossino, Mariano. Universidad del Salvador. Escuela de Veterinaria; Argentina. University of Kentucky. Department of Veterinary Science. Maxwell H. Gluck Equine Research Center; Estados Unidos Fil: Go, Y.Y. Korea Research Institute of Chemical Technology. Division of Drug Discovery Research. Virus Research and Testing Group; Corea Fil: Vincke, Cécile. Vrije Universiteit. Laboratory of Cellular and MolecularImmunology; Bélgica Fil: Balasuriya,Udeni B.R. University of Kentucky. Department of Veterinary Science. Maxwell H. Gluck Equine Research Center; Estados Unidos Fil: Muyldermans, Serge. Vrije Universiteit. Laboratory of Cellular and MolecularImmunology; Bélgica Fil: Wigdorovitz, Andres. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Barrandeguy, Maria Edith. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Universidad del Salvador. Escuela de Veterinaria; Argentina Fil: Parreño, Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina 2017-08-22T17:55:12Z 2017-08-22T17:55:12Z 2016 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion info:ar-repo/semantics/artículo http://hdl.handle.net/20.500.12123/1009 http://www.j-evs.com/article/S0737-0806(16)00154-4/pdf 0737-0806 http://dx.doi.org/10.1016/j.jevs.2016.02.123 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Journal of equine veterinary science 39 : S56eS65 |
| spellingShingle | Animal Diseases Stallions Nanotechnology Equine Arteritis Virus Enfermedades de los Animales Caballos Sementales Nanotecnología Virus de la Arteritis Equina Aduriz Guerrero, Matías Carossino, Mariano Go, Y.Y. Vincke, Cécile Balasuriya, Udeni B.R. Muyldermans, S. Wigdorovitz, Andres Barrandeguy, Maria Edith Parreño, Viviana Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions |
| title | Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions |
| title_full | Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions |
| title_fullStr | Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions |
| title_full_unstemmed | Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions |
| title_short | Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions |
| title_sort | development of recombinant vhh nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions |
| topic | Animal Diseases Stallions Nanotechnology Equine Arteritis Virus Enfermedades de los Animales Caballos Sementales Nanotecnología Virus de la Arteritis Equina |
| url | http://hdl.handle.net/20.500.12123/1009 http://www.j-evs.com/article/S0737-0806(16)00154-4/pdf http://dx.doi.org/10.1016/j.jevs.2016.02.123 |
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