Cows of reproductive age in the high Andean region of Peru have seroprevalence of antibodies against bovine herpesvirus 1 and Neospora caninum

Objective To determine the seroprevalence of infectious agents with reproductive implications in cattle from 3 districts of the high Andean region of Peru over 3,500 m above level sea. Methods 361 blood samples were collected from cows in 3 districts of the Apurimac department using nonprobabilistic...

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Autores principales: Contreras Vílchez, Víctor, Mendoza Palomino, Efrain, Jiménez Aparco, César, Huamán Lizana, Darwin, Acuña Leiva, Alex Tony, Quispe Ccasa, Hurley Abel
Formato: info:eu-repo/semantics/article
Lenguaje:Inglés
Publicado: American Veterinary Medical Association 2025
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12955/2829
https://doi.org/10.2460/ajvr.25.04.0141
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author Contreras Vílchez, Víctor
Mendoza Palomino, Efrain
Jiménez Aparco, César
Huamán Lizana, Darwin
Acuña Leiva, Alex Tony
Quispe Ccasa, Hurley Abel
author_browse Acuña Leiva, Alex Tony
Contreras Vílchez, Víctor
Huamán Lizana, Darwin
Jiménez Aparco, César
Mendoza Palomino, Efrain
Quispe Ccasa, Hurley Abel
author_facet Contreras Vílchez, Víctor
Mendoza Palomino, Efrain
Jiménez Aparco, César
Huamán Lizana, Darwin
Acuña Leiva, Alex Tony
Quispe Ccasa, Hurley Abel
author_sort Contreras Vílchez, Víctor
collection Repositorio INIA
description Objective To determine the seroprevalence of infectious agents with reproductive implications in cattle from 3 districts of the high Andean region of Peru over 3,500 m above level sea. Methods 361 blood samples were collected from cows in 3 districts of the Apurimac department using nonprobabilistic stratified sampling for an exploratory study. Antibodies against Brucella spp, Mycobacterium avium subsp paratuberculosis, bovine viral diarrhea virus, bovine leukemia virus, bluetongue virus, bovine herpesvirus 1 (BHV), and Neospora caninum (NC) were detected by ELISA. Analysis of independence, multiple correspondence, and logistic regression were performed for risk factors, with district, age, and phenotypic traits as predictors. Results The highest seroprevalences were 18.28% BHV and 6.93% NC, with a similar trend at the sector and herd levels. Bovine herpesvirus 1 was predominant in Cotaruse and Oropesa and NC in Oropesa and San Jerónimo. The multiple correspondence analysis explained 42.40% of the structural variability, with greater dispersion observed between seropositives for NC and BHV, without a significant association between seropositivities. The district was a risk factor for NC, with a 95% CI of 0.11 to 0.88 in Cotaruse, although the 95% CI for BHV was 7.33 to 630.75 in Cotaruse and 14.11 to 1,289.94 in Oropesa. Conclusions BHV and NC are seroprevalent in cows from the sampled high Andean herds, and district location is the strongest risk factor. Clinical Relevance Environmental conditions and livestock management practices of the region could explain the seroprevalence rates; however, strengthening surveillance against BHV and NC is imperative to prevent risks of acute or subclinical infections.
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spelling INIA28292025-08-19T17:45:53Z Cows of reproductive age in the high Andean region of Peru have seroprevalence of antibodies against bovine herpesvirus 1 and Neospora caninum Contreras Vílchez, Víctor Mendoza Palomino, Efrain Jiménez Aparco, César Huamán Lizana, Darwin Acuña Leiva, Alex Tony Quispe Ccasa, Hurley Abel high Andean cattle farming epidemiology ELISA bovine herpesvirus 1 Neospora caninum ganadería altoandina epidemiología herpesvirus bovino 1 https://purl.org/pe-repo/ocde/ford#4.02.02 cows; Vaca Objective To determine the seroprevalence of infectious agents with reproductive implications in cattle from 3 districts of the high Andean region of Peru over 3,500 m above level sea. Methods 361 blood samples were collected from cows in 3 districts of the Apurimac department using nonprobabilistic stratified sampling for an exploratory study. Antibodies against Brucella spp, Mycobacterium avium subsp paratuberculosis, bovine viral diarrhea virus, bovine leukemia virus, bluetongue virus, bovine herpesvirus 1 (BHV), and Neospora caninum (NC) were detected by ELISA. Analysis of independence, multiple correspondence, and logistic regression were performed for risk factors, with district, age, and phenotypic traits as predictors. Results The highest seroprevalences were 18.28% BHV and 6.93% NC, with a similar trend at the sector and herd levels. Bovine herpesvirus 1 was predominant in Cotaruse and Oropesa and NC in Oropesa and San Jerónimo. The multiple correspondence analysis explained 42.40% of the structural variability, with greater dispersion observed between seropositives for NC and BHV, without a significant association between seropositivities. The district was a risk factor for NC, with a 95% CI of 0.11 to 0.88 in Cotaruse, although the 95% CI for BHV was 7.33 to 630.75 in Cotaruse and 14.11 to 1,289.94 in Oropesa. Conclusions BHV and NC are seroprevalent in cows from the sampled high Andean herds, and district location is the strongest risk factor. Clinical Relevance Environmental conditions and livestock management practices of the region could explain the seroprevalence rates; however, strengthening surveillance against BHV and NC is imperative to prevent risks of acute or subclinical infections. This research was funded by the project “Mejoramiento de los Servicios de Investigación y Transferencia de Tecnología en Ganadería Alto Andina en las Regiones: Apurímac, Arequipa, Ayacucho, Cusco, Huancavelica, Junín, Moquegua, Pasco, Puno y Tacna, 33 Distritos,” CUI No. 2491159, from the Instituto Nacional de Innovación Agraria. 2025-08-19T17:45:53Z 2025-08-19T17:45:53Z 2025-07-08 info:eu-repo/semantics/article Contreras-Vilchez, V. E., Mendoza-Palomino, E., Jiménez-Aparco, C., Huamán-Lizana, D., Acuña-Leiva, A., & Quispe-Ccasa, H. A. (2025). Cows of reproductive age in the high Andean region of Peru have seroprevalence of antibodies against bovine herpesvirus 1 and Neospora caninum. American Journal of Veterinary Research (published online ahead of print 2025). Retrieved Aug 14, 2025, from https://doi.org/10.2460/ajvr.25.04.0141 1943-5681 http://hdl.handle.net/20.500.12955/2829 https://doi.org/10.2460/ajvr.25.04.0141 eng ursn:issn:1943-5681 American Journal of Veterinary Research info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc/4.0/ application/pdf application/pdf American Veterinary Medical Association US Instituto Nacional de Innovación Agraria Repositorio Institucional - INIA
spellingShingle high Andean cattle farming
epidemiology
ELISA
bovine herpesvirus 1
Neospora caninum
ganadería altoandina
epidemiología
herpesvirus bovino 1
https://purl.org/pe-repo/ocde/ford#4.02.02
cows; Vaca
Contreras Vílchez, Víctor
Mendoza Palomino, Efrain
Jiménez Aparco, César
Huamán Lizana, Darwin
Acuña Leiva, Alex Tony
Quispe Ccasa, Hurley Abel
Cows of reproductive age in the high Andean region of Peru have seroprevalence of antibodies against bovine herpesvirus 1 and Neospora caninum
title Cows of reproductive age in the high Andean region of Peru have seroprevalence of antibodies against bovine herpesvirus 1 and Neospora caninum
title_full Cows of reproductive age in the high Andean region of Peru have seroprevalence of antibodies against bovine herpesvirus 1 and Neospora caninum
title_fullStr Cows of reproductive age in the high Andean region of Peru have seroprevalence of antibodies against bovine herpesvirus 1 and Neospora caninum
title_full_unstemmed Cows of reproductive age in the high Andean region of Peru have seroprevalence of antibodies against bovine herpesvirus 1 and Neospora caninum
title_short Cows of reproductive age in the high Andean region of Peru have seroprevalence of antibodies against bovine herpesvirus 1 and Neospora caninum
title_sort cows of reproductive age in the high andean region of peru have seroprevalence of antibodies against bovine herpesvirus 1 and neospora caninum
topic high Andean cattle farming
epidemiology
ELISA
bovine herpesvirus 1
Neospora caninum
ganadería altoandina
epidemiología
herpesvirus bovino 1
https://purl.org/pe-repo/ocde/ford#4.02.02
cows; Vaca
url http://hdl.handle.net/20.500.12955/2829
https://doi.org/10.2460/ajvr.25.04.0141
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