Effects of age in fecal microbiota and correlations with blood parameters in genetic nucleus of cattle
This study aimed to determine the impact of age on the fecal microbiota in the genetic nucleus of cattle, with a focus on microbial richness, composition, functional diversity, and correlations with blood parameters. Fecal and blood samples from 21 cattle were analyzed using 16S rRNA gene sequencing...
| Autores principales: | , , , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
MDPI
2024
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/20.500.12955/2540 https://doi.org/10.3390/microorganisms12071331 |
| _version_ | 1855490334763515904 |
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| author | Estrada Cañari, Richard Romero Avila, Yolanda Madelein Figueroa Venegas, Deyanira Antonella Coila Añasco, Pedro Ubaldo Hañari Quispe, Renán Dilton Aliaga, Mery Galindo, Walter Alvarado Chuqui, Wigoberto Casanova Nuñez Melgar, David Pavel Quilcate Pairazamán, Carlos Enrique |
| author_browse | Aliaga, Mery Alvarado Chuqui, Wigoberto Casanova Nuñez Melgar, David Pavel Coila Añasco, Pedro Ubaldo Estrada Cañari, Richard Figueroa Venegas, Deyanira Antonella Galindo, Walter Hañari Quispe, Renán Dilton Quilcate Pairazamán, Carlos Enrique Romero Avila, Yolanda Madelein |
| author_facet | Estrada Cañari, Richard Romero Avila, Yolanda Madelein Figueroa Venegas, Deyanira Antonella Coila Añasco, Pedro Ubaldo Hañari Quispe, Renán Dilton Aliaga, Mery Galindo, Walter Alvarado Chuqui, Wigoberto Casanova Nuñez Melgar, David Pavel Quilcate Pairazamán, Carlos Enrique |
| author_sort | Estrada Cañari, Richard |
| collection | Repositorio INIA |
| description | This study aimed to determine the impact of age on the fecal microbiota in the genetic nucleus of cattle, with a focus on microbial richness, composition, functional diversity, and correlations with blood parameters. Fecal and blood samples from 21 cattle were analyzed using 16S rRNA gene sequencing. Older cattle exhibited greater bacterial diversity and abundance, with significant changes in alpha diversity indices (p < 0.05). Beta diversity analysis revealed significant variations in microbial composition between age groups and the interaction of age and sex (p < 0.05). Correlations between alpha diversity, community composition, and hematological values highlighted the influence of microbiota on bovine health. Beneficial butyrate-producing bacteria, such as Ruminococcaceae, were more abundant in older cattle, suggesting a role in gut health. Functional diversity analysis indicated that younger cattle had significantly more abundant metabolic pathways in fermentation and anaerobic chemoheterotrophy. These findings suggest management strategies including tailored probiotic therapies, dietary adjustments, and targeted health monitoring to enhance livestock health and performance. Further research should include comprehensive metabolic analyses to better correlate microbiota changes with age-related variations, enhancing understanding of the complex interactions between microbiota, age, and reproductive status. |
| format | Artículo |
| id | INIA2540 |
| institution | Institucional Nacional de Innovación Agraria |
| language | Inglés |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | INIA25402025-05-26T01:05:39Z Effects of age in fecal microbiota and correlations with blood parameters in genetic nucleus of cattle Estrada Cañari, Richard Romero Avila, Yolanda Madelein Figueroa Venegas, Deyanira Antonella Coila Añasco, Pedro Ubaldo Hañari Quispe, Renán Dilton Aliaga, Mery Galindo, Walter Alvarado Chuqui, Wigoberto Casanova Nuñez Melgar, David Pavel Quilcate Pairazamán, Carlos Enrique Cattle fecal microbiota Age-related changes 16S rRNA gene sequencing Blood parameters Functional diversity https://purl.org/pe-repo/ocde/ford#4.02.01 Cattle Ganado bovino Microbial flora Flora microbiana Nucleotide sequence Secuencia nucleotídica Parameters Parámetro This study aimed to determine the impact of age on the fecal microbiota in the genetic nucleus of cattle, with a focus on microbial richness, composition, functional diversity, and correlations with blood parameters. Fecal and blood samples from 21 cattle were analyzed using 16S rRNA gene sequencing. Older cattle exhibited greater bacterial diversity and abundance, with significant changes in alpha diversity indices (p < 0.05). Beta diversity analysis revealed significant variations in microbial composition between age groups and the interaction of age and sex (p < 0.05). Correlations between alpha diversity, community composition, and hematological values highlighted the influence of microbiota on bovine health. Beneficial butyrate-producing bacteria, such as Ruminococcaceae, were more abundant in older cattle, suggesting a role in gut health. Functional diversity analysis indicated that younger cattle had significantly more abundant metabolic pathways in fermentation and anaerobic chemoheterotrophy. These findings suggest management strategies including tailored probiotic therapies, dietary adjustments, and targeted health monitoring to enhance livestock health and performance. Further research should include comprehensive metabolic analyses to better correlate microbiota changes with age-related variations, enhancing understanding of the complex interactions between microbiota, age, and reproductive status. CUI 2432072 Proyecto: “Mejoramiento de la disponibilidad de material genético de ganado bovino con alto valor a nivel nacional 7 departamentos” 2024-07-12T05:19:06Z 2024-07-12T05:19:06Z 2024-06-29 info:eu-repo/semantics/article Estrada-Cañari, R.; Romero, Y.; Figueroa-Venegas, D. A.; Coila, P.; Hañari-Quispe, R. D.; Aliaga, M.; Galindo, W.; Alvarado, W.; Casanova-Nuñez-Melgar, D. P.; & Quilcate-Pairazamán, C. E. (2024). Effects of age in fecal microbiota and correlations with blood parameters in genetic nucleus of cattle. Microorganisms, 12(7), 1331. doi: 10.3390/microorganisms12071331 2076-2607 https://hdl.handle.net/20.500.12955/2540 https://doi.org/10.3390/microorganisms12071331 eng urn:issn:2076-2607 Microorganisms info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/ application/pdf application/pdf MDPI CH Instituto Nacional de Innovación Agraria Repositorio Institucional - INIA |
| spellingShingle | Cattle fecal microbiota Age-related changes 16S rRNA gene sequencing Blood parameters Functional diversity https://purl.org/pe-repo/ocde/ford#4.02.01 Cattle Ganado bovino Microbial flora Flora microbiana Nucleotide sequence Secuencia nucleotídica Parameters Parámetro Estrada Cañari, Richard Romero Avila, Yolanda Madelein Figueroa Venegas, Deyanira Antonella Coila Añasco, Pedro Ubaldo Hañari Quispe, Renán Dilton Aliaga, Mery Galindo, Walter Alvarado Chuqui, Wigoberto Casanova Nuñez Melgar, David Pavel Quilcate Pairazamán, Carlos Enrique Effects of age in fecal microbiota and correlations with blood parameters in genetic nucleus of cattle |
| title | Effects of age in fecal microbiota and correlations with blood parameters in genetic nucleus of cattle |
| title_full | Effects of age in fecal microbiota and correlations with blood parameters in genetic nucleus of cattle |
| title_fullStr | Effects of age in fecal microbiota and correlations with blood parameters in genetic nucleus of cattle |
| title_full_unstemmed | Effects of age in fecal microbiota and correlations with blood parameters in genetic nucleus of cattle |
| title_short | Effects of age in fecal microbiota and correlations with blood parameters in genetic nucleus of cattle |
| title_sort | effects of age in fecal microbiota and correlations with blood parameters in genetic nucleus of cattle |
| topic | Cattle fecal microbiota Age-related changes 16S rRNA gene sequencing Blood parameters Functional diversity https://purl.org/pe-repo/ocde/ford#4.02.01 Cattle Ganado bovino Microbial flora Flora microbiana Nucleotide sequence Secuencia nucleotídica Parameters Parámetro |
| url | https://hdl.handle.net/20.500.12955/2540 https://doi.org/10.3390/microorganisms12071331 |
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