Parasitism-induced changes in microbial eukaryotes of Peruvian alpaca gastrointestinal tract
Alpacas, important genetic resources in the Andean region of Peru, are vulnerable to diarrhea caused by pathogenic parasites such as Eimeria lamae and Giardia sp., which can be fatal, especially in neonates, due to their physiological immaturity and limited adaptability. The study investigated the d...
| Autores principales: | , , , , , , , , , |
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| Formato: | info:eu-repo/semantics/article |
| Lenguaje: | Inglés |
| Publicado: |
MDPI
2024
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/20.500.12955/2446 https://doi.org/10.3390/life14020187 |
| _version_ | 1855028880722624512 |
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| author | Sanchez, Diana Zapata Coacalla, Celso Romero Avila, Yolanda Flores Huarco, Nils Herber Oros, Oscar Alvarado Chuqui, Wigoberto Quilcate Pairazamán, Carlos Enrique Guevara Alvarado, Hada María Estrada Cañari, Richard Coila Añasco, Pedro Ubaldo |
| author_browse | Alvarado Chuqui, Wigoberto Coila Añasco, Pedro Ubaldo Estrada Cañari, Richard Flores Huarco, Nils Herber Guevara Alvarado, Hada María Oros, Oscar Quilcate Pairazamán, Carlos Enrique Romero Avila, Yolanda Sanchez, Diana Zapata Coacalla, Celso |
| author_facet | Sanchez, Diana Zapata Coacalla, Celso Romero Avila, Yolanda Flores Huarco, Nils Herber Oros, Oscar Alvarado Chuqui, Wigoberto Quilcate Pairazamán, Carlos Enrique Guevara Alvarado, Hada María Estrada Cañari, Richard Coila Añasco, Pedro Ubaldo |
| author_sort | Sanchez, Diana |
| collection | Repositorio INIA |
| description | Alpacas, important genetic resources in the Andean region of Peru, are vulnerable to diarrhea caused by pathogenic parasites such as Eimeria lamae and Giardia sp., which can be fatal, especially in neonates, due to their physiological immaturity and limited adaptability. The study investigated the diversity and abundance of intestinal fungi and protists in alpacas infected with Eimeria lamae and Giardia sp. compared to healthy alpacas. A total of 19 alpacas, aged between one and two months, were included. They were divided into two groups, one with pathological conditions (nine) and the other healthy (ten). Parasitological analyses for the detection of parasites and subsequent molecular analysis were performed on the collected fecal samples. The results revealed a greater diversity and abundance of protists in infected alpacas in comparison with healthy alpacas, while the fungal composition did not show significant changes. Therefore, parasitic infections affect the protist component of the alpaca gut microbiota. Also, it was observed that Blastocystis was identified in all healthy alpacas, serving as a possible marker of the health of the intestinal microbiota; in addition, Prussia and Pichia are beneficial fungi that help control diseases. This groundbreaking study in neonatal alpacas is the first to explore potential changes in the intestinal microbiota during an infectious state, underscoring the importance of further research to comprehend its effects on alpaca health and immune responses. |
| format | info:eu-repo/semantics/article |
| id | INIA2446 |
| institution | Institucional Nacional de Innovación Agraria |
| language | Inglés |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | INIA24462025-03-09T15:08:56Z Parasitism-induced changes in microbial eukaryotes of Peruvian alpaca gastrointestinal tract Sanchez, Diana Zapata Coacalla, Celso Romero Avila, Yolanda Flores Huarco, Nils Herber Oros, Oscar Alvarado Chuqui, Wigoberto Quilcate Pairazamán, Carlos Enrique Guevara Alvarado, Hada María Estrada Cañari, Richard Coila Añasco, Pedro Ubaldo Alpacas Metabarcoding Microbiota diversity Parasites Biomarkers NGS https://purl.org/pe-repo/ocde/ford#4.02.01 Alpacas Alpaca Parasites Parásitos Digestive system Sistema digestivo Alpacas, important genetic resources in the Andean region of Peru, are vulnerable to diarrhea caused by pathogenic parasites such as Eimeria lamae and Giardia sp., which can be fatal, especially in neonates, due to their physiological immaturity and limited adaptability. The study investigated the diversity and abundance of intestinal fungi and protists in alpacas infected with Eimeria lamae and Giardia sp. compared to healthy alpacas. A total of 19 alpacas, aged between one and two months, were included. They were divided into two groups, one with pathological conditions (nine) and the other healthy (ten). Parasitological analyses for the detection of parasites and subsequent molecular analysis were performed on the collected fecal samples. The results revealed a greater diversity and abundance of protists in infected alpacas in comparison with healthy alpacas, while the fungal composition did not show significant changes. Therefore, parasitic infections affect the protist component of the alpaca gut microbiota. Also, it was observed that Blastocystis was identified in all healthy alpacas, serving as a possible marker of the health of the intestinal microbiota; in addition, Prussia and Pichia are beneficial fungi that help control diseases. This groundbreaking study in neonatal alpacas is the first to explore potential changes in the intestinal microbiota during an infectious state, underscoring the importance of further research to comprehend its effects on alpaca health and immune responses. 2024-02-28T21:33:49Z 2024-02-28T21:33:49Z 2024-01-27 info:eu-repo/semantics/article Sanchez, D.; Zapata, C.; Romero, Y.; Flores-Huarco, N. H.; Oros, O.; Alvarado, W. C.; ... & Coila, P. (2024). Parasitism-induced changes in microbial eukaryotes of Peruvian alpaca gastrointestinal tract. Life, 14(2), 187. doi: 10.3390/life14020187 2075-1729 https://hdl.handle.net/20.500.12955/2446 https://doi.org/10.3390/life14020187 eng Life Life info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/ application/pdf application/pdf MDPI CH Instituto Nacional de Innovación Agraria Repositorio Institucional - INIA |
| spellingShingle | Alpacas Metabarcoding Microbiota diversity Parasites Biomarkers NGS https://purl.org/pe-repo/ocde/ford#4.02.01 Alpacas Alpaca Parasites Parásitos Digestive system Sistema digestivo Sanchez, Diana Zapata Coacalla, Celso Romero Avila, Yolanda Flores Huarco, Nils Herber Oros, Oscar Alvarado Chuqui, Wigoberto Quilcate Pairazamán, Carlos Enrique Guevara Alvarado, Hada María Estrada Cañari, Richard Coila Añasco, Pedro Ubaldo Parasitism-induced changes in microbial eukaryotes of Peruvian alpaca gastrointestinal tract |
| title | Parasitism-induced changes in microbial eukaryotes of Peruvian alpaca gastrointestinal tract |
| title_full | Parasitism-induced changes in microbial eukaryotes of Peruvian alpaca gastrointestinal tract |
| title_fullStr | Parasitism-induced changes in microbial eukaryotes of Peruvian alpaca gastrointestinal tract |
| title_full_unstemmed | Parasitism-induced changes in microbial eukaryotes of Peruvian alpaca gastrointestinal tract |
| title_short | Parasitism-induced changes in microbial eukaryotes of Peruvian alpaca gastrointestinal tract |
| title_sort | parasitism induced changes in microbial eukaryotes of peruvian alpaca gastrointestinal tract |
| topic | Alpacas Metabarcoding Microbiota diversity Parasites Biomarkers NGS https://purl.org/pe-repo/ocde/ford#4.02.01 Alpacas Alpaca Parasites Parásitos Digestive system Sistema digestivo |
| url | https://hdl.handle.net/20.500.12955/2446 https://doi.org/10.3390/life14020187 |
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