First draft genome assembly of the Peruvian creole cattle breed (Bos taurus) and its comparative genomics among the Bovinae subfamily

The Peruvian creole cattle (PCC) is a neglected breed, and is an essential livestock resource in the Andean region of Peru. To develop a modern breeding program and conservation strategies for the PCC, a better understanding of the genetics of this breed is needed. We sequenced the whole genome of t...

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Autores principales: Estrada Cañari, Richard, Corredor Arizapana, Flor Anita, Figueroa Venegas, Deyanira Antonella, Salazar Coronel, Wilian, Quilcate Pairazamán, Carlos Enrique, Vásquez Pérez, Héctor Vladimir, Maicelo Quintana, Jorge Luis, Gonzales, Jhony, Arbizu Berrocal, Carlos Irvin
Formato: Artículo preliminar
Lenguaje:Inglés
Publicado: MDPI 2023
Materias:
Acceso en línea:https://hdl.handle.net/20.500.12955/2271
https://doi.org/10.20944/preprints202208.0349.v1
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author Estrada Cañari, Richard
Corredor Arizapana, Flor Anita
Figueroa Venegas, Deyanira Antonella
Salazar Coronel, Wilian
Quilcate Pairazamán, Carlos Enrique
Vásquez Pérez, Héctor Vladimir
Maicelo Quintana, Jorge Luis
Gonzales, Jhony
Arbizu Berrocal, Carlos Irvin
author_browse Arbizu Berrocal, Carlos Irvin
Corredor Arizapana, Flor Anita
Estrada Cañari, Richard
Figueroa Venegas, Deyanira Antonella
Gonzales, Jhony
Maicelo Quintana, Jorge Luis
Quilcate Pairazamán, Carlos Enrique
Salazar Coronel, Wilian
Vásquez Pérez, Héctor Vladimir
author_facet Estrada Cañari, Richard
Corredor Arizapana, Flor Anita
Figueroa Venegas, Deyanira Antonella
Salazar Coronel, Wilian
Quilcate Pairazamán, Carlos Enrique
Vásquez Pérez, Héctor Vladimir
Maicelo Quintana, Jorge Luis
Gonzales, Jhony
Arbizu Berrocal, Carlos Irvin
author_sort Estrada Cañari, Richard
collection Repositorio INIA
description The Peruvian creole cattle (PCC) is a neglected breed, and is an essential livestock resource in the Andean region of Peru. To develop a modern breeding program and conservation strategies for the PCC, a better understanding of the genetics of this breed is needed. We sequenced the whole genome of the PCC using a paired-end 150 strategy on the Illumina HiSeq 2500 platform, obtaining 320 GB of sequencing data. The obtained genome size of the PCC was 2.77 Gb with a contig N50 of 108Mb and 92.59% complete BUSCOs. Also, we identified 40.22% of repetitive DNA of the genome assembly, of which retroelements occupy 32.39% of the total genome. A total of 19,803 protein-coding genes were annotated in the PCC genome. We downloaded proteomes and genomes of the Bovinae subfamily, and conducted a comparative analysis with our draft genome. Phylogenomic analysis showed that PCC is related to Bos indicus. Also, we identified 7,746 family genes shared among the Bovinae subfamily. This first PCC genome is expected to contribute to a better understanding of its genetics to adapt to the tough conditions of the Andean ecosystem, and evolution.
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spelling INIA22712024-01-26T21:41:51Z First draft genome assembly of the Peruvian creole cattle breed (Bos taurus) and its comparative genomics among the Bovinae subfamily Estrada Cañari, Richard Corredor Arizapana, Flor Anita Figueroa Venegas, Deyanira Antonella Salazar Coronel, Wilian Quilcate Pairazamán, Carlos Enrique Vásquez Pérez, Héctor Vladimir Maicelo Quintana, Jorge Luis Gonzales, Jhony Arbizu Berrocal, Carlos Irvin NGS Andean Neglected breed Genome https://purl.org/pe-repo/ocde/ford#4.02.01 Genomes Genomas Bos Taurus The Peruvian creole cattle (PCC) is a neglected breed, and is an essential livestock resource in the Andean region of Peru. To develop a modern breeding program and conservation strategies for the PCC, a better understanding of the genetics of this breed is needed. We sequenced the whole genome of the PCC using a paired-end 150 strategy on the Illumina HiSeq 2500 platform, obtaining 320 GB of sequencing data. The obtained genome size of the PCC was 2.77 Gb with a contig N50 of 108Mb and 92.59% complete BUSCOs. Also, we identified 40.22% of repetitive DNA of the genome assembly, of which retroelements occupy 32.39% of the total genome. A total of 19,803 protein-coding genes were annotated in the PCC genome. We downloaded proteomes and genomes of the Bovinae subfamily, and conducted a comparative analysis with our draft genome. Phylogenomic analysis showed that PCC is related to Bos indicus. Also, we identified 7,746 family genes shared among the Bovinae subfamily. This first PCC genome is expected to contribute to a better understanding of its genetics to adapt to the tough conditions of the Andean ecosystem, and evolution. 2023-08-31T17:33:41Z 2023-08-31T17:33:41Z 2022-08-18 info:eu-repo/semantics/workingPaper Estrada, R.; Corredor, F. A.; Figueroa, D.; Salazar, W.; Quilcate, C.; Vásquez, H. V.; ... & Arbizu, C. I. (2022). First draft genome assembly of the Peruvian creole cattle breed (Bos taurus) and its comparative genomics among the Bovinae subfamily. Preprints, doi: 10.20944/preprints202208.0349.v1 https://hdl.handle.net/20.500.12955/2271 https://doi.org/10.20944/preprints202208.0349.v1 eng Preprints info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/ application/pdf application/pdf MDPI CH Instituto Nacional de Innovación Agraria Repositorio Institucional - INIA
spellingShingle NGS
Andean
Neglected breed
Genome
https://purl.org/pe-repo/ocde/ford#4.02.01
Genomes
Genomas
Bos Taurus
Estrada Cañari, Richard
Corredor Arizapana, Flor Anita
Figueroa Venegas, Deyanira Antonella
Salazar Coronel, Wilian
Quilcate Pairazamán, Carlos Enrique
Vásquez Pérez, Héctor Vladimir
Maicelo Quintana, Jorge Luis
Gonzales, Jhony
Arbizu Berrocal, Carlos Irvin
First draft genome assembly of the Peruvian creole cattle breed (Bos taurus) and its comparative genomics among the Bovinae subfamily
title First draft genome assembly of the Peruvian creole cattle breed (Bos taurus) and its comparative genomics among the Bovinae subfamily
title_full First draft genome assembly of the Peruvian creole cattle breed (Bos taurus) and its comparative genomics among the Bovinae subfamily
title_fullStr First draft genome assembly of the Peruvian creole cattle breed (Bos taurus) and its comparative genomics among the Bovinae subfamily
title_full_unstemmed First draft genome assembly of the Peruvian creole cattle breed (Bos taurus) and its comparative genomics among the Bovinae subfamily
title_short First draft genome assembly of the Peruvian creole cattle breed (Bos taurus) and its comparative genomics among the Bovinae subfamily
title_sort first draft genome assembly of the peruvian creole cattle breed bos taurus and its comparative genomics among the bovinae subfamily
topic NGS
Andean
Neglected breed
Genome
https://purl.org/pe-repo/ocde/ford#4.02.01
Genomes
Genomas
Bos Taurus
url https://hdl.handle.net/20.500.12955/2271
https://doi.org/10.20944/preprints202208.0349.v1
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