Exploration of the production of three Thiodiketopiperazines by an endophytic fungal strain of Cophinforma mamane
Endophytic fungi possess a versatile metabolism which is related to their ability to live in diverse ecological niches. While culturing under laboratory conditions, their metabolism is mainly influenced by the culture media, time of incubation and other physicochemical factors. In this study, we foc...
| Autores principales: | , , , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Wiley-Blackwell
2023
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/20.500.12955/2193 https://doi.org/10.1002/cbdv.202201087 |
| _version_ | 1855490451009699840 |
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| author | Pacheco Tapia, Romina Ortíz, Sergio Jargeat, Patricia Amasifuen Guerra, Carlos Alberto Vansteelandt, Marieke Haddad, Mohamed |
| author_browse | Amasifuen Guerra, Carlos Alberto Haddad, Mohamed Jargeat, Patricia Ortíz, Sergio Pacheco Tapia, Romina Vansteelandt, Marieke |
| author_facet | Pacheco Tapia, Romina Ortíz, Sergio Jargeat, Patricia Amasifuen Guerra, Carlos Alberto Vansteelandt, Marieke Haddad, Mohamed |
| author_sort | Pacheco Tapia, Romina |
| collection | Repositorio INIA |
| description | Endophytic fungi possess a versatile metabolism which is related to their ability to live in diverse ecological niches. While culturing under laboratory conditions, their metabolism is mainly influenced by the culture media, time of incubation and other physicochemical factors. In this study, we focused on the production of 3 thiodiketopiperazines (TDKPs) botryosulfuranols A−C produced by an endophytic strain of Cophinforma mamane isolated from the leaves of Bixa orellana L collected in the Peruvian Amazon. We studied the time-course production of botryosulfuranols A−C during 28 days and evaluated the variations in the production of secondary metabolites, including the TDKPs, produced by C. mamane in response to different culture media, light versus dark conditions and different incubation times. We observed a short time-frame production of botryosulfuranol C while its production was significantly affected by the light conditions and nutrients of the culture media. Botryosulfuranols A and B showed a similar production pattern and a similar response to culturing conditions. Molecular networking allowed us to detect three compounds related to TDKPs that will be the focus of future experiments. |
| format | Artículo |
| id | INIA2193 |
| institution | Institucional Nacional de Innovación Agraria |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Wiley-Blackwell |
| publisherStr | Wiley-Blackwell |
| record_format | dspace |
| spelling | INIA21932025-05-25T23:57:36Z Exploration of the production of three Thiodiketopiperazines by an endophytic fungal strain of Cophinforma mamane Pacheco Tapia, Romina Ortíz, Sergio Jargeat, Patricia Amasifuen Guerra, Carlos Alberto Vansteelandt, Marieke Haddad, Mohamed Thiodiketopiperazines Cophinforma mamane Endophytic fungi Bixa orellana https://purl.org/pe-repo/ocde/ford#4.01.02 Endophytes Endofitas Bixa orellana Endophytic fungi possess a versatile metabolism which is related to their ability to live in diverse ecological niches. While culturing under laboratory conditions, their metabolism is mainly influenced by the culture media, time of incubation and other physicochemical factors. In this study, we focused on the production of 3 thiodiketopiperazines (TDKPs) botryosulfuranols A−C produced by an endophytic strain of Cophinforma mamane isolated from the leaves of Bixa orellana L collected in the Peruvian Amazon. We studied the time-course production of botryosulfuranols A−C during 28 days and evaluated the variations in the production of secondary metabolites, including the TDKPs, produced by C. mamane in response to different culture media, light versus dark conditions and different incubation times. We observed a short time-frame production of botryosulfuranol C while its production was significantly affected by the light conditions and nutrients of the culture media. Botryosulfuranols A and B showed a similar production pattern and a similar response to culturing conditions. Molecular networking allowed us to detect three compounds related to TDKPs that will be the focus of future experiments. 2023-06-05T17:35:40Z 2023-06-05T17:35:40Z 2023-03-15 info:eu-repo/semantics/article Pacheco-Tapia, R.; Ortiz, S.; Jargeat, P.; Amasifuen, C.; Vansteelandt, M.; & Haddad, M. (2023). Exploration of the production of three Thiodiketopiperazines by an endophytic fungal strain of Cophinforma mamane. Chemistry & Biodiversity, e202201087. doi: 10.1002/cbdv.202201087 1612-1872 https://hdl.handle.net/20.500.12955/2193 https://doi.org/10.1002/cbdv.202201087 eng urn:issn:1612-1872 Chemistry and Biodiversity info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/ application/pdf Wiley-Blackwell CH Instituto Nacional de Innovación Agraria Repositorio Institucional - INIA |
| spellingShingle | Thiodiketopiperazines Cophinforma mamane Endophytic fungi Bixa orellana https://purl.org/pe-repo/ocde/ford#4.01.02 Endophytes Endofitas Bixa orellana Pacheco Tapia, Romina Ortíz, Sergio Jargeat, Patricia Amasifuen Guerra, Carlos Alberto Vansteelandt, Marieke Haddad, Mohamed Exploration of the production of three Thiodiketopiperazines by an endophytic fungal strain of Cophinforma mamane |
| title | Exploration of the production of three Thiodiketopiperazines by an endophytic fungal strain of Cophinforma mamane |
| title_full | Exploration of the production of three Thiodiketopiperazines by an endophytic fungal strain of Cophinforma mamane |
| title_fullStr | Exploration of the production of three Thiodiketopiperazines by an endophytic fungal strain of Cophinforma mamane |
| title_full_unstemmed | Exploration of the production of three Thiodiketopiperazines by an endophytic fungal strain of Cophinforma mamane |
| title_short | Exploration of the production of three Thiodiketopiperazines by an endophytic fungal strain of Cophinforma mamane |
| title_sort | exploration of the production of three thiodiketopiperazines by an endophytic fungal strain of cophinforma mamane |
| topic | Thiodiketopiperazines Cophinforma mamane Endophytic fungi Bixa orellana https://purl.org/pe-repo/ocde/ford#4.01.02 Endophytes Endofitas Bixa orellana |
| url | https://hdl.handle.net/20.500.12955/2193 https://doi.org/10.1002/cbdv.202201087 |
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