Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru
The objective of this study was to identify genetic single nucleotide polymorphisms (SNPs) in the coding region of the KRTAP11.1 gene from the Suri alpaca population from Puno, Peru. Genomic DNA (n = 119) was used to amplify the 636 bp fragment of the coding region from the KRTAP11.1 gene. The polym...
| Autores principales: | , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
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Kasetsart University
2023
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/20.500.12955/2191 https://doi.org/10.34044/j.anres.2019.53.1.15 |
| _version_ | 1855490413374210048 |
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| author | Gallegos, Roberto Rodriguez, Jorge Quiñones, Ivana Delgado De la Flor, Irene Huanca Mamani, Teodosio De la Cruz Perez, Abigail Espinoza, José R. |
| author_browse | De la Cruz Perez, Abigail Delgado De la Flor, Irene Espinoza, José R. Gallegos, Roberto Huanca Mamani, Teodosio Quiñones, Ivana Rodriguez, Jorge |
| author_facet | Gallegos, Roberto Rodriguez, Jorge Quiñones, Ivana Delgado De la Flor, Irene Huanca Mamani, Teodosio De la Cruz Perez, Abigail Espinoza, José R. |
| author_sort | Gallegos, Roberto |
| collection | Repositorio INIA |
| description | The objective of this study was to identify genetic single nucleotide polymorphisms (SNPs) in the coding region of the KRTAP11.1 gene from the Suri alpaca population from Puno, Peru. Genomic DNA (n = 119) was used to amplify the 636 bp fragment of the coding region from the KRTAP11.1 gene. The polymerase chain reaction products of the KRTAP11.1 gene were sequenced by both strands and polymorphism type SNPs were identified. All SNPs (n = 3) were in Hardy-Weinberg equilibrium and had a high level of genotypic linkage disequilibrium with the presence of two haplotypes. All genetic polymorphisms generate non-synonymous amino acids changes: SNP 110 T>G (Ser>Ala), SNP 363 T>G (Phe>Cys) and SNP 375 A>C (Tyr>Ser). The results indicated the presence of moderate genetic diversity in the coding region of the KRTAP11.1 gene from the Suri alpaca population. |
| format | Artículo |
| id | INIA2191 |
| institution | Institucional Nacional de Innovación Agraria |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Kasetsart University |
| publisherStr | Kasetsart University |
| record_format | dspace |
| spelling | INIA21912023-07-07T16:20:08Z Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru Gallegos, Roberto Rodriguez, Jorge Quiñones, Ivana Delgado De la Flor, Irene Huanca Mamani, Teodosio De la Cruz Perez, Abigail Espinoza, José R. Alpaca KAP11.1 gene Keratin associated protein Single nucleotide polymorphisms (SNPs) Suri https://purl.org/pe-repo/ocde/ford#4.02.01 Alpacas Alpaca Single Nucleotide Polymorphism Polimorfismo de un solo nucleótido The objective of this study was to identify genetic single nucleotide polymorphisms (SNPs) in the coding region of the KRTAP11.1 gene from the Suri alpaca population from Puno, Peru. Genomic DNA (n = 119) was used to amplify the 636 bp fragment of the coding region from the KRTAP11.1 gene. The polymerase chain reaction products of the KRTAP11.1 gene were sequenced by both strands and polymorphism type SNPs were identified. All SNPs (n = 3) were in Hardy-Weinberg equilibrium and had a high level of genotypic linkage disequilibrium with the presence of two haplotypes. All genetic polymorphisms generate non-synonymous amino acids changes: SNP 110 T>G (Ser>Ala), SNP 363 T>G (Phe>Cys) and SNP 375 A>C (Tyr>Ser). The results indicated the presence of moderate genetic diversity in the coding region of the KRTAP11.1 gene from the Suri alpaca population. 2023-06-05T17:34:39Z 2023-06-05T17:34:39Z 2019-02-28 info:eu-repo/semantics/article Gallegos, R.; Rodriguez, J.; Quiñones, I.; Delgado-de-la-Flor, I.; Huanca, T.; de la Cruz Perez, A.; & Espinoza, J. (2019). Genetic variation in KRTAP11. 1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru. Agriculture and Natural Resources, 53(1), 87-88. doi: 10.34044/j.anres.2019.53.1.15 2452-316X https://hdl.handle.net/20.500.12955/2191 https://doi.org/10.34044/j.anres.2019.53.1.15 eng urn:issn:2452-316X Agriculture and Natural Resources info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Kasetsart University TH Instituto Nacional de Innovación Agraria Repositorio Institucional - INIA |
| spellingShingle | Alpaca KAP11.1 gene Keratin associated protein Single nucleotide polymorphisms (SNPs) Suri https://purl.org/pe-repo/ocde/ford#4.02.01 Alpacas Alpaca Single Nucleotide Polymorphism Polimorfismo de un solo nucleótido Gallegos, Roberto Rodriguez, Jorge Quiñones, Ivana Delgado De la Flor, Irene Huanca Mamani, Teodosio De la Cruz Perez, Abigail Espinoza, José R. Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru |
| title | Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru |
| title_full | Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru |
| title_fullStr | Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru |
| title_full_unstemmed | Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru |
| title_short | Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru |
| title_sort | genetic variation in krtap11 1 gene of suri alpaca vicugna pacos from puno peru |
| topic | Alpaca KAP11.1 gene Keratin associated protein Single nucleotide polymorphisms (SNPs) Suri https://purl.org/pe-repo/ocde/ford#4.02.01 Alpacas Alpaca Single Nucleotide Polymorphism Polimorfismo de un solo nucleótido |
| url | https://hdl.handle.net/20.500.12955/2191 https://doi.org/10.34044/j.anres.2019.53.1.15 |
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