Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon

Among 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 ± 51.4 μg TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative ef...

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Main Authors: Tauchen, Jan, Bortl, Ludvik, Huml, Lukas, Miksatkova, Petra, Doskocil, Ivo, Marsik, Petr, Panduro Villegas, Pablo Pedro, Bendezu Flores, Ymber, Van Damme, Patrick, Lojka, Bohdan, Havlik, Jaroslav, Lapcik, Oldrich, Kokoska, Ladislav
Format: info:eu-repo/semantics/article
Language:Inglés
Published: El Sevier 2020
Subjects:
Online Access:https://repositorio.inia.gob.pe/handle/20.500.12955/1143
http://dx.doi.org/10.1016/j.bjp.2016.03.016
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author Tauchen, Jan
Bortl, Ludvik
Huml, Lukas
Miksatkova, Petra
Doskocil, Ivo
Marsik, Petr
Panduro Villegas, Pablo Pedro
Bendezu Flores, Ymber
Van Damme, Patrick
Lojka, Bohdan
Havlik, Jaroslav
Lapcik, Oldrich
Kokoska, Ladislav
author_browse Bendezu Flores, Ymber
Bortl, Ludvik
Doskocil, Ivo
Havlik, Jaroslav
Huml, Lukas
Kokoska, Ladislav
Lapcik, Oldrich
Lojka, Bohdan
Marsik, Petr
Miksatkova, Petra
Panduro Villegas, Pablo Pedro
Tauchen, Jan
Van Damme, Patrick
author_facet Tauchen, Jan
Bortl, Ludvik
Huml, Lukas
Miksatkova, Petra
Doskocil, Ivo
Marsik, Petr
Panduro Villegas, Pablo Pedro
Bendezu Flores, Ymber
Van Damme, Patrick
Lojka, Bohdan
Havlik, Jaroslav
Lapcik, Oldrich
Kokoska, Ladislav
author_sort Tauchen, Jan
collection Repositorio INIA
description Among 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 ± 51.4 μg TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative effect (IC50 for Hep-G2 and HT-29 = 2.7 and 9.0 μg/ml, respectively). However, combinatory antioxidant/anti-proliferative effect was only detected in Oenocarpus bataua Mart., Arecaceae (DPPH = 903.8 and ORAC = 1024 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 102.6 and 38.8 μg/ml, respectively) and Inga edulis Mart., Fabaceae (DPPH = 337.0 and ORAC = 795.7 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 36.3 and 57.9 μg/ml, respectively). Phenolic content was positively correlated with antioxidant potential, however not with anti-proliferative effect. None of these extracts possessed toxicity towards normal foetal lung cells, suggesting their possible use in development of novel plant-based agents with preventive and/or therapeutic action against oxidative stress-related diseases.
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spelling INIA11432022-11-21T20:33:45Z Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon Tauchen, Jan Bortl, Ludvik Huml, Lukas Miksatkova, Petra Doskocil, Ivo Marsik, Petr Panduro Villegas, Pablo Pedro Bendezu Flores, Ymber Van Damme, Patrick Lojka, Bohdan Havlik, Jaroslav Lapcik, Oldrich Kokoska, Ladislav Antioxidant Anticarcinogenic Phenolic compounds Plant extracts Biotecnología agrícola, Biotecnología alimentaria Among 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 ± 51.4 μg TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative effect (IC50 for Hep-G2 and HT-29 = 2.7 and 9.0 μg/ml, respectively). However, combinatory antioxidant/anti-proliferative effect was only detected in Oenocarpus bataua Mart., Arecaceae (DPPH = 903.8 and ORAC = 1024 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 102.6 and 38.8 μg/ml, respectively) and Inga edulis Mart., Fabaceae (DPPH = 337.0 and ORAC = 795.7 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 36.3 and 57.9 μg/ml, respectively). Phenolic content was positively correlated with antioxidant potential, however not with anti-proliferative effect. None of these extracts possessed toxicity towards normal foetal lung cells, suggesting their possible use in development of novel plant-based agents with preventive and/or therapeutic action against oxidative stress-related diseases. Introduction. Materials and methods. Results. Discussion. Conclusion. References. 2020-10-03T01:22:17Z 2020-10-03T01:22:17Z 2016-06-14 info:eu-repo/semantics/article Tauchen, J.; Bortl, L.; Huml, L.; Miksatkova, P.; Doskocil, I.; Marsik, P.; Panduro, P.; Bendezu, Y.; Van Damme, P.; Lojka, B.; Havlik, J.; Lapcik, O.; Kokoska, L. (2016). Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon. Revista Brasileira de Farmacognosia Volume 26, Issue 6, Pages 728-737. doi: 10.1016/j.bjp.2016.03.016 https://repositorio.inia.gob.pe/handle/20.500.12955/1143 Revista Brasileira de Farmacognosia http://dx.doi.org/10.1016/j.bjp.2016.03.016 eng Revista Brasileira de Farmacognosia Volume 26, Issue 6, November–December 2016, Pages 728-737 http://dx.doi.org/10.1016/j.bjp.2016.03.016 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/ application/pdf application/pdf Perú El Sevier Brasil Instituto Nacional de Innovación Agraria Repositorio Institucional - INIA
spellingShingle Antioxidant
Anticarcinogenic
Phenolic compounds
Plant extracts
Biotecnología agrícola, Biotecnología alimentaria
Tauchen, Jan
Bortl, Ludvik
Huml, Lukas
Miksatkova, Petra
Doskocil, Ivo
Marsik, Petr
Panduro Villegas, Pablo Pedro
Bendezu Flores, Ymber
Van Damme, Patrick
Lojka, Bohdan
Havlik, Jaroslav
Lapcik, Oldrich
Kokoska, Ladislav
Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title_full Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title_fullStr Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title_full_unstemmed Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title_short Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title_sort phenolic composition antioxidant and anti proliferative activities of edible and medicinal plants from the peruvian amazon
topic Antioxidant
Anticarcinogenic
Phenolic compounds
Plant extracts
Biotecnología agrícola, Biotecnología alimentaria
url https://repositorio.inia.gob.pe/handle/20.500.12955/1143
http://dx.doi.org/10.1016/j.bjp.2016.03.016
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