Assessment of iron bioavailability from twenty elite latematuring tropical maize varieties using an in vitro digestion/Caco2 cell model

An in vitro digestion/Caco-2 cell model was used to assess iron bioavailability of twenty elite late-maturing tropical maize varieties grown in three diverse agroecologies in West and Central Africa (WCA). Kernel-iron concentration of the varieties, averaged across locations, varied from 19.2 to 24....

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Autores principales: Oikeh, S.O., Menkir, A., Maziya-Dixon, B.B., Welch, R.M., Glahn, Raymond P.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wiley 2004
Materias:
Acceso en línea:https://hdl.handle.net/10568/96400
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author Oikeh, S.O.
Menkir, A.
Maziya-Dixon, B.B.
Welch, R.M.
Glahn, Raymond P.
author_browse Glahn, Raymond P.
Maziya-Dixon, B.B.
Menkir, A.
Oikeh, S.O.
Welch, R.M.
author_facet Oikeh, S.O.
Menkir, A.
Maziya-Dixon, B.B.
Welch, R.M.
Glahn, Raymond P.
author_sort Oikeh, S.O.
collection Repository of Agricultural Research Outputs (CGSpace)
description An in vitro digestion/Caco-2 cell model was used to assess iron bioavailability of twenty elite late-maturing tropical maize varieties grown in three diverse agroecologies in West and Central Africa (WCA). Kernel-iron concentration of the varieties, averaged across locations, varied from 19.2 to 24.4 mg kg−1, while mean kernel-zinc concentration ranged between 19.4 and 24.6 mg kg−1. Significant differences in iron bioavailability were observed among varieties, but the environment had no significant effect. Mean bioavailable iron ranged between 14% below and 43% above the reference control variety, TZB-SR. Variety DMR-LSR-Y with the highest concentrations of kernel-iron and -zinc of 24–25 mg kg−1 across the three locations had a similar quantity of bioavailable iron as the reference control, TZB-SR. In the long run this variety could be potentially effective in reducing iron deficiency because of its high kernel-iron. The most promising varieties were Mid-altitude STR synthetic and ACR91SUWAN-1-SRC1. They had kernel-iron and -zinc levels of 22–24 mg kg−1 and bioavailable iron 24–36% higher than the reference control, TZB-SR. Additional research is necessary to determine if the increases in kernel-iron concentration and bioavailable iron observed in this study can significantly improve the iron status of individuals in WCA at risk for iron deficiency.
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spelling CGSpace964002024-08-27T10:35:46Z Assessment of iron bioavailability from twenty elite latematuring tropical maize varieties using an in vitro digestion/Caco2 cell model Oikeh, S.O. Menkir, A. Maziya-Dixon, B.B. Welch, R.M. Glahn, Raymond P. maize bioavailability An in vitro digestion/Caco-2 cell model was used to assess iron bioavailability of twenty elite late-maturing tropical maize varieties grown in three diverse agroecologies in West and Central Africa (WCA). Kernel-iron concentration of the varieties, averaged across locations, varied from 19.2 to 24.4 mg kg−1, while mean kernel-zinc concentration ranged between 19.4 and 24.6 mg kg−1. Significant differences in iron bioavailability were observed among varieties, but the environment had no significant effect. Mean bioavailable iron ranged between 14% below and 43% above the reference control variety, TZB-SR. Variety DMR-LSR-Y with the highest concentrations of kernel-iron and -zinc of 24–25 mg kg−1 across the three locations had a similar quantity of bioavailable iron as the reference control, TZB-SR. In the long run this variety could be potentially effective in reducing iron deficiency because of its high kernel-iron. The most promising varieties were Mid-altitude STR synthetic and ACR91SUWAN-1-SRC1. They had kernel-iron and -zinc levels of 22–24 mg kg−1 and bioavailable iron 24–36% higher than the reference control, TZB-SR. Additional research is necessary to determine if the increases in kernel-iron concentration and bioavailable iron observed in this study can significantly improve the iron status of individuals in WCA at risk for iron deficiency. 2004-08-15 2018-08-09T06:40:37Z 2018-08-09T06:40:37Z Journal Article https://hdl.handle.net/10568/96400 en Limited Access Wiley Oikeh, S.O., Menkir, A., Maziya‐Dixon, B., Welch, R.M. & Glahn, R.P. (2004). Assessment of iron bioavailability from twenty elite late‐maturing tropical maize varieties using an in vitro digestion/Caco‐2 cell model. Journal of the Science of Food and Agriculture, 84(10), 1202-1206.
spellingShingle maize
bioavailability
Oikeh, S.O.
Menkir, A.
Maziya-Dixon, B.B.
Welch, R.M.
Glahn, Raymond P.
Assessment of iron bioavailability from twenty elite latematuring tropical maize varieties using an in vitro digestion/Caco2 cell model
title Assessment of iron bioavailability from twenty elite latematuring tropical maize varieties using an in vitro digestion/Caco2 cell model
title_full Assessment of iron bioavailability from twenty elite latematuring tropical maize varieties using an in vitro digestion/Caco2 cell model
title_fullStr Assessment of iron bioavailability from twenty elite latematuring tropical maize varieties using an in vitro digestion/Caco2 cell model
title_full_unstemmed Assessment of iron bioavailability from twenty elite latematuring tropical maize varieties using an in vitro digestion/Caco2 cell model
title_short Assessment of iron bioavailability from twenty elite latematuring tropical maize varieties using an in vitro digestion/Caco2 cell model
title_sort assessment of iron bioavailability from twenty elite latematuring tropical maize varieties using an in vitro digestion caco2 cell model
topic maize
bioavailability
url https://hdl.handle.net/10568/96400
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