Opportunities and Challenges to Implementing Genomic Selection in Clonally Propagated Crops

Clonal propagation of fruits, flowers, and forest trees leads to high levels of heterozygosity, fixes favorable combinations of traits, eliminates undesirable deleterious effects, allows easy identification, propagation of favorable mutations, and is an efficient method for in vitro and ex vitro mai...

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Main Authors: Gemenet, D., Khan, A.
Format: Book Chapter
Language:Inglés
Published: Springer 2017
Subjects:
Online Access:https://hdl.handle.net/10568/92953
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author Gemenet, D.
Khan, A.
author_browse Gemenet, D.
Khan, A.
author_facet Gemenet, D.
Khan, A.
author_sort Gemenet, D.
collection Repository of Agricultural Research Outputs (CGSpace)
description Clonal propagation of fruits, flowers, and forest trees leads to high levels of heterozygosity, fixes favorable combinations of traits, eliminates undesirable deleterious effects, allows easy identification, propagation of favorable mutations, and is an efficient method for in vitro and ex vitro maintenance and conservation. However, these same characteristics pose challenges to genetic improvement. Many clonal fruits and forest trees have a long juvenile phase, extensive outcrossing, widespread hybridization, limited population structure, multiple origins, and ongoing crop–wild gene flow, and have suffered from domestication bottlenecks, and are polyploid. Breeding clonal crops requires a crossing step involving two heterozygous parents, as a break to create genetic variation that can be exploited during selection in subsequent cycles, before reverting to clonal selection. The presence of several segregating alleles, overdominance and epistatic interactions, at each locus of highly heterozygous clonal crop decreases efficiency of phenotypic selection in breeding programs and genetic studies. Genomic selection (GS) that uses genome-wide genotypic data to predict the phenotypic performance of a genotype by estimating its breeding value has the potential to increase efficiency of clonal crop breeding. In this chapter, potential use and challenges of GS to expedite the breeding process in clonally propagated crops are discussed, with examples. We identify challenges associated with specific features of clonal crops to be addressed in GS models and highlight development of improved marker and bioinformatics platforms to distinguish between paralogous copies and to incorporate partial heterozygosity and allele dosage determination.
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spelling CGSpace929532023-12-27T19:48:31Z Opportunities and Challenges to Implementing Genomic Selection in Clonally Propagated Crops Gemenet, D. Khan, A. clones crops genotype environment interaction genetics heritability breeding Clonal propagation of fruits, flowers, and forest trees leads to high levels of heterozygosity, fixes favorable combinations of traits, eliminates undesirable deleterious effects, allows easy identification, propagation of favorable mutations, and is an efficient method for in vitro and ex vitro maintenance and conservation. However, these same characteristics pose challenges to genetic improvement. Many clonal fruits and forest trees have a long juvenile phase, extensive outcrossing, widespread hybridization, limited population structure, multiple origins, and ongoing crop–wild gene flow, and have suffered from domestication bottlenecks, and are polyploid. Breeding clonal crops requires a crossing step involving two heterozygous parents, as a break to create genetic variation that can be exploited during selection in subsequent cycles, before reverting to clonal selection. The presence of several segregating alleles, overdominance and epistatic interactions, at each locus of highly heterozygous clonal crop decreases efficiency of phenotypic selection in breeding programs and genetic studies. Genomic selection (GS) that uses genome-wide genotypic data to predict the phenotypic performance of a genotype by estimating its breeding value has the potential to increase efficiency of clonal crop breeding. In this chapter, potential use and challenges of GS to expedite the breeding process in clonally propagated crops are discussed, with examples. We identify challenges associated with specific features of clonal crops to be addressed in GS models and highlight development of improved marker and bioinformatics platforms to distinguish between paralogous copies and to incorporate partial heterozygosity and allele dosage determination. 2017 2018-05-29T16:23:06Z 2018-05-29T16:23:06Z Book Chapter https://hdl.handle.net/10568/92953 en Limited Access Springer Gemenet, D.C.; Khan, A. 2017. Opportunities and challenges to implementing genomic selection in clonally propagated crops. In: Varshney R.; Roorkiwal M.; Sorrells M. (eds.). Genomic selection for crop improvement. New molecular breeding strategies for crop improvement. Cham (Switzerland). Springer International Publishing. ISBN 978-3-319-63168-4. pp. 185-198.
spellingShingle clones
crops
genotype environment interaction
genetics
heritability
breeding
Gemenet, D.
Khan, A.
Opportunities and Challenges to Implementing Genomic Selection in Clonally Propagated Crops
title Opportunities and Challenges to Implementing Genomic Selection in Clonally Propagated Crops
title_full Opportunities and Challenges to Implementing Genomic Selection in Clonally Propagated Crops
title_fullStr Opportunities and Challenges to Implementing Genomic Selection in Clonally Propagated Crops
title_full_unstemmed Opportunities and Challenges to Implementing Genomic Selection in Clonally Propagated Crops
title_short Opportunities and Challenges to Implementing Genomic Selection in Clonally Propagated Crops
title_sort opportunities and challenges to implementing genomic selection in clonally propagated crops
topic clones
crops
genotype environment interaction
genetics
heritability
breeding
url https://hdl.handle.net/10568/92953
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