Genomic sequence derived simple sequence repeat markers: case study with Medicago spp

Simple sequence repeats (SSR) or micro-satellites are becoming standard DNA markers for plant genome analysis and are being used as markers in marker assisted breeding. De novo generation of micro-satellite markers through laboratory-based screening of SSR-enriched genomic libraries is highly time c...

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Autores principales: Mahalakshmi, V., Aparana, P., Ramadevi, S., Ortíz, R.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Elsevier 2002
Materias:
Acceso en línea:https://hdl.handle.net/10568/92745
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author Mahalakshmi, V.
Aparana, P.
Ramadevi, S.
Ortíz, R.
author_browse Aparana, P.
Mahalakshmi, V.
Ortíz, R.
Ramadevi, S.
author_facet Mahalakshmi, V.
Aparana, P.
Ramadevi, S.
Ortíz, R.
author_sort Mahalakshmi, V.
collection Repository of Agricultural Research Outputs (CGSpace)
description Simple sequence repeats (SSR) or micro-satellites are becoming standard DNA markers for plant genome analysis and are being used as markers in marker assisted breeding. De novo generation of micro-satellite markers through laboratory-based screening of SSR-enriched genomic libraries is highly time consuming and expensive. An alternative is to screen the public databases of related model species where abundant sequence data is already available. All the genomic sequences of Medicago from the public domain database were searched and analysed of di, tri, and tetra nucleotide repeats. Of the total of about 156,000 sequences which were searched, 7325 sequences were found to contain repeat motif and may yield SSR which will yield product sizes of around 200 bp. Of these the most abundantly found repeats were the tri-nucleotide (5210) group. Except for a very small proportion (436), these link to the gene annotation database at TIGR (http://www.tigr.org).
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spelling CGSpace927452025-11-12T05:34:21Z Genomic sequence derived simple sequence repeat markers: case study with Medicago spp Mahalakshmi, V. Aparana, P. Ramadevi, S. Ortíz, R. bioinformatics genetic markers repeat motifs simple sequence repeats ssr Simple sequence repeats (SSR) or micro-satellites are becoming standard DNA markers for plant genome analysis and are being used as markers in marker assisted breeding. De novo generation of micro-satellite markers through laboratory-based screening of SSR-enriched genomic libraries is highly time consuming and expensive. An alternative is to screen the public databases of related model species where abundant sequence data is already available. All the genomic sequences of Medicago from the public domain database were searched and analysed of di, tri, and tetra nucleotide repeats. Of the total of about 156,000 sequences which were searched, 7325 sequences were found to contain repeat motif and may yield SSR which will yield product sizes of around 200 bp. Of these the most abundantly found repeats were the tri-nucleotide (5210) group. Except for a very small proportion (436), these link to the gene annotation database at TIGR (http://www.tigr.org). 2002 2018-05-17T09:03:22Z 2018-05-17T09:03:22Z Journal Article https://hdl.handle.net/10568/92745 en Open Access application/pdf Elsevier Mahalakshmi, V., Aparna, P., Ramadevi, S. & Ortiz, R. (2002). Genomic sequence derived simple sequence repeats markers a case study with Medicago spp. Electronic Journal of Biotechnology, 5(3), 13-14.
spellingShingle bioinformatics
genetic markers
repeat motifs
simple sequence repeats
ssr
Mahalakshmi, V.
Aparana, P.
Ramadevi, S.
Ortíz, R.
Genomic sequence derived simple sequence repeat markers: case study with Medicago spp
title Genomic sequence derived simple sequence repeat markers: case study with Medicago spp
title_full Genomic sequence derived simple sequence repeat markers: case study with Medicago spp
title_fullStr Genomic sequence derived simple sequence repeat markers: case study with Medicago spp
title_full_unstemmed Genomic sequence derived simple sequence repeat markers: case study with Medicago spp
title_short Genomic sequence derived simple sequence repeat markers: case study with Medicago spp
title_sort genomic sequence derived simple sequence repeat markers case study with medicago spp
topic bioinformatics
genetic markers
repeat motifs
simple sequence repeats
ssr
url https://hdl.handle.net/10568/92745
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