Mitochondrial DNA variation reveals maternal origins and demographic dynamics of Ethiopian indigenous goats
The Horn of Africa forms one of the two main historical entry points of domestics into the continent and Ethiopia is particularly important in this regard. Through the analysis of mitochondrial DNA (mtDNA) d-loop region in 309 individuals from 13 populations, we reveal the maternal genetic variation...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Wiley
2018
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/92067 |
| _version_ | 1855537777702076416 |
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| author | Mekuriaw, Getinet Tesfaye, K. Okeyo Mwai, Ally Djikeng, Appolinaire Dessie, Tadelle Birungi, Josephine Osama, S. Zergaw, N. Alemu, A. Achieng, G. Tutah, J. Mutai, C. Njuguna, J. Mwacharo, Joram M. |
| author_browse | Achieng, G. Alemu, A. Birungi, Josephine Dessie, Tadelle Djikeng, Appolinaire Mekuriaw, Getinet Mutai, C. Mwacharo, Joram M. Njuguna, J. Okeyo Mwai, Ally Osama, S. Tesfaye, K. Tutah, J. Zergaw, N. |
| author_facet | Mekuriaw, Getinet Tesfaye, K. Okeyo Mwai, Ally Djikeng, Appolinaire Dessie, Tadelle Birungi, Josephine Osama, S. Zergaw, N. Alemu, A. Achieng, G. Tutah, J. Mutai, C. Njuguna, J. Mwacharo, Joram M. |
| author_sort | Mekuriaw, Getinet |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | The Horn of Africa forms one of the two main historical entry points of domestics into the continent and Ethiopia is particularly important in this regard. Through the analysis of mitochondrial DNA (mtDNA) d-loop region in 309 individuals from 13 populations, we reveal the maternal genetic variation and demographic dynamics of Ethiopian indigenous goats. A total of 174 variable sites that generated 231 haplotypes were observed. They defined two haplogroups that were present in all the 13 study populations. Reference haplotypes from the six globally defined goat mtDNA haplogroups show the two haplogroups present in Ethiopia to be A and G, the former being the most predominant. Although both haplogroups are characterized by an increase in effective population sizes (Ne) predating domestication, they also have experienced a decline in Ne at different time periods, suggesting different demographic histories. We observed seven haplotypes, six were directly linked to the central haplotypes of the two haplogroups and one was central to haplogroup G. The seven haplotypes were common between Ethiopia, Kenya, Egypt, and Saudi Arabia populations, suggesting common maternal history and the introduction of goats into East Africa via Egypt and the Arabian Peninsula, respectively. While providing new mtDNA data from a historically important region, our results suggest extensive intermixing of goats mediated by human socio-cultural and economic interactions. These have led to the coexistence of the two haplogroups in different geographic regions in Ethiopia resulting in a large caprine genetic diversity that can be exploited for genetic improvement. |
| format | Journal Article |
| id | CGSpace92067 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2018 |
| publishDateRange | 2018 |
| publishDateSort | 2018 |
| publisher | Wiley |
| publisherStr | Wiley |
| record_format | dspace |
| spelling | CGSpace920672024-03-05T09:20:56Z Mitochondrial DNA variation reveals maternal origins and demographic dynamics of Ethiopian indigenous goats Mekuriaw, Getinet Tesfaye, K. Okeyo Mwai, Ally Djikeng, Appolinaire Dessie, Tadelle Birungi, Josephine Osama, S. Zergaw, N. Alemu, A. Achieng, G. Tutah, J. Mutai, C. Njuguna, J. Mwacharo, Joram M. animal breeding genetics goats small ruminants The Horn of Africa forms one of the two main historical entry points of domestics into the continent and Ethiopia is particularly important in this regard. Through the analysis of mitochondrial DNA (mtDNA) d-loop region in 309 individuals from 13 populations, we reveal the maternal genetic variation and demographic dynamics of Ethiopian indigenous goats. A total of 174 variable sites that generated 231 haplotypes were observed. They defined two haplogroups that were present in all the 13 study populations. Reference haplotypes from the six globally defined goat mtDNA haplogroups show the two haplogroups present in Ethiopia to be A and G, the former being the most predominant. Although both haplogroups are characterized by an increase in effective population sizes (Ne) predating domestication, they also have experienced a decline in Ne at different time periods, suggesting different demographic histories. We observed seven haplotypes, six were directly linked to the central haplotypes of the two haplogroups and one was central to haplogroup G. The seven haplotypes were common between Ethiopia, Kenya, Egypt, and Saudi Arabia populations, suggesting common maternal history and the introduction of goats into East Africa via Egypt and the Arabian Peninsula, respectively. While providing new mtDNA data from a historically important region, our results suggest extensive intermixing of goats mediated by human socio-cultural and economic interactions. These have led to the coexistence of the two haplogroups in different geographic regions in Ethiopia resulting in a large caprine genetic diversity that can be exploited for genetic improvement. 2018-02 2018-04-12T19:30:53Z 2018-04-12T19:30:53Z Journal Article https://hdl.handle.net/10568/92067 en Open Access Wiley Mekuriaw, G., Tesfaye, K., Mwai, O.A., Djikeng, A., Dessie, T., Birungi, J., Osama, S., Zergaw, N., Alemu, A., Achieng, G., Tutah, J., Mutai, C., Njuguna, J. and Mwacharo, J.M. 2018. Mitochondrial DNA variation reveals maternal origins and demographic dynamics of Ethiopian indigenous goats. Ecology and Evolution 8(3):1543–1553. |
| spellingShingle | animal breeding genetics goats small ruminants Mekuriaw, Getinet Tesfaye, K. Okeyo Mwai, Ally Djikeng, Appolinaire Dessie, Tadelle Birungi, Josephine Osama, S. Zergaw, N. Alemu, A. Achieng, G. Tutah, J. Mutai, C. Njuguna, J. Mwacharo, Joram M. Mitochondrial DNA variation reveals maternal origins and demographic dynamics of Ethiopian indigenous goats |
| title | Mitochondrial DNA variation reveals maternal origins and demographic dynamics of Ethiopian indigenous goats |
| title_full | Mitochondrial DNA variation reveals maternal origins and demographic dynamics of Ethiopian indigenous goats |
| title_fullStr | Mitochondrial DNA variation reveals maternal origins and demographic dynamics of Ethiopian indigenous goats |
| title_full_unstemmed | Mitochondrial DNA variation reveals maternal origins and demographic dynamics of Ethiopian indigenous goats |
| title_short | Mitochondrial DNA variation reveals maternal origins and demographic dynamics of Ethiopian indigenous goats |
| title_sort | mitochondrial dna variation reveals maternal origins and demographic dynamics of ethiopian indigenous goats |
| topic | animal breeding genetics goats small ruminants |
| url | https://hdl.handle.net/10568/92067 |
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