Iron bioavailability and utilization in rots fed cassava based complementary diets

The study evaluated the iron bioavailability and utilization in rats fed cassava-based complementary diets. Bioavailability and utilization were determined in Sprague-Dawley rats using the iron balance and hemoglobin depletion-repletion methods in a 6 x 8 randomized block design. Rats were depleted...

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Autores principales: Onabanjo, O.O., Maziya-Dixon, B.B., Oguntona, C.R., Olayiwola, I.O., Oguntona, B.E., Dixon, Alfred G.O.
Formato: Journal Article
Lenguaje:Inglés
Publicado: 2008
Materias:
Acceso en línea:https://hdl.handle.net/10568/90851
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author Onabanjo, O.O.
Maziya-Dixon, B.B.
Oguntona, C.R.
Olayiwola, I.O.
Oguntona, B.E.
Dixon, Alfred G.O.
author_browse Dixon, Alfred G.O.
Maziya-Dixon, B.B.
Oguntona, B.E.
Oguntona, C.R.
Olayiwola, I.O.
Onabanjo, O.O.
author_facet Onabanjo, O.O.
Maziya-Dixon, B.B.
Oguntona, C.R.
Olayiwola, I.O.
Oguntona, B.E.
Dixon, Alfred G.O.
author_sort Onabanjo, O.O.
collection Repository of Agricultural Research Outputs (CGSpace)
description The study evaluated the iron bioavailability and utilization in rats fed cassava-based complementary diets. Bioavailability and utilization were determined in Sprague-Dawley rats using the iron balance and hemoglobin depletion-repletion methods in a 6 x 8 randomized block design. Rats were depleted by feeding them a low iron casein diet for 14 days. During the repletion period, the rats were fed four composite diets formulated using iron improved cassava varieties as the base ingredients. Hemoglobin was determined at the end of depletion and repletion periods. Iron bioavailability expressed as hemoglobin regeneration efficiency (HRE) was higher in the rats that consumed the positive control diet than in those fed test (improved with iron) diets. The present study also found an inverse correlation between diet iron content and bioavailability (r = - 0.88, P < 0.05), and a direct relationship between the gain in hemoglobin and iron utilization (r = 0.95, P < 0.05). Further, most of the rats recovered their hemoglobin and packed cell volume status after repletion (Hb > 12 g/dl) except for rat fed the negative control suggesting that iron was poorly utilized. The study confirmed that the overall iron bioavailability expressed as hemoglobin regeneration efficiency (HRE) from composite flour formulated from cassava is low.
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spelling CGSpace908512023-06-12T21:38:30Z Iron bioavailability and utilization in rots fed cassava based complementary diets Onabanjo, O.O. Maziya-Dixon, B.B. Oguntona, C.R. Olayiwola, I.O. Oguntona, B.E. Dixon, Alfred G.O. iron bioavailability iron utilization complementary food improved cassava composite flours rats The study evaluated the iron bioavailability and utilization in rats fed cassava-based complementary diets. Bioavailability and utilization were determined in Sprague-Dawley rats using the iron balance and hemoglobin depletion-repletion methods in a 6 x 8 randomized block design. Rats were depleted by feeding them a low iron casein diet for 14 days. During the repletion period, the rats were fed four composite diets formulated using iron improved cassava varieties as the base ingredients. Hemoglobin was determined at the end of depletion and repletion periods. Iron bioavailability expressed as hemoglobin regeneration efficiency (HRE) was higher in the rats that consumed the positive control diet than in those fed test (improved with iron) diets. The present study also found an inverse correlation between diet iron content and bioavailability (r = - 0.88, P < 0.05), and a direct relationship between the gain in hemoglobin and iron utilization (r = 0.95, P < 0.05). Further, most of the rats recovered their hemoglobin and packed cell volume status after repletion (Hb > 12 g/dl) except for rat fed the negative control suggesting that iron was poorly utilized. The study confirmed that the overall iron bioavailability expressed as hemoglobin regeneration efficiency (HRE) from composite flour formulated from cassava is low. 2008 2018-02-06T12:15:05Z 2018-02-06T12:15:05Z Journal Article https://hdl.handle.net/10568/90851 en Limited Access Onabanjo, O.O., Maziya-Dixon, B., Oguntona, C.R., Olayiwola, I.O., Oguntona, B.E. & Dixon, A.G. (2008). Iron bioavailability and utilization in rats fed cassava-based complementary diets. Journal of Food, Agriculture & Environment, 6(3&4), 210-214.
spellingShingle iron bioavailability
iron utilization
complementary food
improved cassava
composite flours
rats
Onabanjo, O.O.
Maziya-Dixon, B.B.
Oguntona, C.R.
Olayiwola, I.O.
Oguntona, B.E.
Dixon, Alfred G.O.
Iron bioavailability and utilization in rots fed cassava based complementary diets
title Iron bioavailability and utilization in rots fed cassava based complementary diets
title_full Iron bioavailability and utilization in rots fed cassava based complementary diets
title_fullStr Iron bioavailability and utilization in rots fed cassava based complementary diets
title_full_unstemmed Iron bioavailability and utilization in rots fed cassava based complementary diets
title_short Iron bioavailability and utilization in rots fed cassava based complementary diets
title_sort iron bioavailability and utilization in rots fed cassava based complementary diets
topic iron bioavailability
iron utilization
complementary food
improved cassava
composite flours
rats
url https://hdl.handle.net/10568/90851
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