Review of immunological methods for the quantification of aflatoxins in peanut and other foods

Aflatoxin contamination is widespread instaple crops like peanut, maize, sorghum, pearlmillet, chillies, pistachio, cassava etc., and com-promises the safety of food and feed supplies. It isimportant to be able to detect and quantifyaflatoxins in commodities to prot...

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Autores principales: Waliyar, Farid, Reddy, S.V., Kumar, P. Lava
Formato: Journal Article
Lenguaje:Inglés
Publicado: 2009
Materias:
Acceso en línea:https://hdl.handle.net/10568/90183
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author Waliyar, Farid
Reddy, S.V.
Kumar, P. Lava
author_browse Kumar, P. Lava
Reddy, S.V.
Waliyar, Farid
author_facet Waliyar, Farid
Reddy, S.V.
Kumar, P. Lava
author_sort Waliyar, Farid
collection Repository of Agricultural Research Outputs (CGSpace)
description Aflatoxin contamination is widespread instaple crops like peanut, maize, sorghum, pearlmillet, chillies, pistachio, cassava etc., and com-promises the safety of food and feed supplies. It isimportant to be able to detect and quantifyaflatoxins in commodities to protect human andanimal health. Many different methods, includingantibody-based ones, are available for quantita-tive estimation of aflatoxins. However, most ofthese methods such as HPLC, HPTLC, and TLCare expensive and/or difficult to use in developedcountries. Using the state-of-the-art facilities atICRISAT, we developed polyclonal and mono-clonal antibodies for the detection of totalaflatoxins, aflatoxin B1 and M1 (secreted in milk).These were used to develop a simple andinexpensive competitive enzyme-linked immuno-sorbent assays (cELISA) that has lower detectionlimits (1.0mg/kg) and cost (about $1 per sample)less than other available methods. More than 100samples can be analyzed in a day. These tests haveprovided a unique opportunity for ICRISAT andits partners to conduct field studies to selectresistant genotypes, identify high risk populationsand determine the dietary sources to stimulateappropriate interventions to enhance the food andhuman health safety, trade and thereby farmers’income
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spelling CGSpace901832024-01-17T12:58:34Z Review of immunological methods for the quantification of aflatoxins in peanut and other foods Waliyar, Farid Reddy, S.V. Kumar, P. Lava peanut arachis hypogaea competitive elisa immunological methods aflatoxins genotypes chromatography polyclonal Aflatoxin contamination is widespread instaple crops like peanut, maize, sorghum, pearlmillet, chillies, pistachio, cassava etc., and com-promises the safety of food and feed supplies. It isimportant to be able to detect and quantifyaflatoxins in commodities to protect human andanimal health. Many different methods, includingantibody-based ones, are available for quantita-tive estimation of aflatoxins. However, most ofthese methods such as HPLC, HPTLC, and TLCare expensive and/or difficult to use in developedcountries. Using the state-of-the-art facilities atICRISAT, we developed polyclonal and mono-clonal antibodies for the detection of totalaflatoxins, aflatoxin B1 and M1 (secreted in milk).These were used to develop a simple andinexpensive competitive enzyme-linked immuno-sorbent assays (cELISA) that has lower detectionlimits (1.0mg/kg) and cost (about $1 per sample)less than other available methods. More than 100samples can be analyzed in a day. These tests haveprovided a unique opportunity for ICRISAT andits partners to conduct field studies to selectresistant genotypes, identify high risk populationsand determine the dietary sources to stimulateappropriate interventions to enhance the food andhuman health safety, trade and thereby farmers’income 2009 2018-01-15T10:50:46Z 2018-01-15T10:50:46Z Journal Article https://hdl.handle.net/10568/90183 en Limited Access Waliyar, F., Reddy, S.V. & Kumar, P.L. (2009). Review of immunological methods for the quantification of aflatoxins in peanut and other foods. Peanut Science, 36(1), 54-59.
spellingShingle peanut
arachis hypogaea
competitive elisa
immunological methods
aflatoxins
genotypes
chromatography
polyclonal
Waliyar, Farid
Reddy, S.V.
Kumar, P. Lava
Review of immunological methods for the quantification of aflatoxins in peanut and other foods
title Review of immunological methods for the quantification of aflatoxins in peanut and other foods
title_full Review of immunological methods for the quantification of aflatoxins in peanut and other foods
title_fullStr Review of immunological methods for the quantification of aflatoxins in peanut and other foods
title_full_unstemmed Review of immunological methods for the quantification of aflatoxins in peanut and other foods
title_short Review of immunological methods for the quantification of aflatoxins in peanut and other foods
title_sort review of immunological methods for the quantification of aflatoxins in peanut and other foods
topic peanut
arachis hypogaea
competitive elisa
immunological methods
aflatoxins
genotypes
chromatography
polyclonal
url https://hdl.handle.net/10568/90183
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