Linkage analysis of a rare alkaloid present in a tetraploid potato with Solanum chacoense background

The potato genotype ND4382-19 has Solanum chacoense Bitt. in its genetic background. Foliar alkaloid analysis of it and its progeny ND5873 (ND4382-19 × Chipeta) by gas chromatography–mass spectrometry (GC–MS) showed that, in addition to the expected alkaloids (solanidine, leptinidine, and acetyl-lep...

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Main Authors: Sagredo, B., Lorenzen, J.H., Casper, H., Lafta, A.
Format: Journal Article
Language:Inglés
Published: Springer 2011
Subjects:
Online Access:https://hdl.handle.net/10568/89078
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author Sagredo, B.
Lorenzen, J.H.
Casper, H.
Lafta, A.
author_browse Casper, H.
Lafta, A.
Lorenzen, J.H.
Sagredo, B.
author_facet Sagredo, B.
Lorenzen, J.H.
Casper, H.
Lafta, A.
author_sort Sagredo, B.
collection Repository of Agricultural Research Outputs (CGSpace)
description The potato genotype ND4382-19 has Solanum chacoense Bitt. in its genetic background. Foliar alkaloid analysis of it and its progeny ND5873 (ND4382-19 × Chipeta) by gas chromatography–mass spectrometry (GC–MS) showed that, in addition to the expected alkaloids (solanidine, leptinidine, and acetyl-leptinidine), there was an aglycone of another rare alkaloid. Its molecular mass and some of the m/z fragment ions were similar to leptinidine, but the major fragment ion was the m/z 150 peak of solanidine. This fragmentation pattern suggested that this alkaloid is a solanidine-based compound with mass equal to leptinidine. Leptinidine differs from solanidine by an extra –OH group, but the GC–MS fragmentation pattern of the rare compound indicated hydroxylation at a different position than the C-23 of leptinidine. The exact chemical structure is still unknown, and further analysis, such as NMR will be necessary to determine the structure. Segregation analysis of ND5873 (ND4382-19 × Chipeta) showed that presence of this rare compound segregated in a 1:1 ratio, indicating that a single gene controlled its synthesis and/or accumulation in foliar tissue. Analysis with AFLP and microsatellite markers indicated that the locus-controlling presence of this alkaloid resided on potato chromosome I, with the nearest flanking AFLP markers 0.6 and 9.4 cM apart. This rare alkaloid was present in the foliage and not detected in potato tubers. Its presence in leaves did not affect resistance/susceptibility to Colorado potato beetle.
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spelling CGSpace890782023-12-08T19:36:04Z Linkage analysis of a rare alkaloid present in a tetraploid potato with Solanum chacoense background Sagredo, B. Lorenzen, J.H. Casper, H. Lafta, A. potato genotypes solanum chacoense alkaloid tetraploid potato The potato genotype ND4382-19 has Solanum chacoense Bitt. in its genetic background. Foliar alkaloid analysis of it and its progeny ND5873 (ND4382-19 × Chipeta) by gas chromatography–mass spectrometry (GC–MS) showed that, in addition to the expected alkaloids (solanidine, leptinidine, and acetyl-leptinidine), there was an aglycone of another rare alkaloid. Its molecular mass and some of the m/z fragment ions were similar to leptinidine, but the major fragment ion was the m/z 150 peak of solanidine. This fragmentation pattern suggested that this alkaloid is a solanidine-based compound with mass equal to leptinidine. Leptinidine differs from solanidine by an extra –OH group, but the GC–MS fragmentation pattern of the rare compound indicated hydroxylation at a different position than the C-23 of leptinidine. The exact chemical structure is still unknown, and further analysis, such as NMR will be necessary to determine the structure. Segregation analysis of ND5873 (ND4382-19 × Chipeta) showed that presence of this rare compound segregated in a 1:1 ratio, indicating that a single gene controlled its synthesis and/or accumulation in foliar tissue. Analysis with AFLP and microsatellite markers indicated that the locus-controlling presence of this alkaloid resided on potato chromosome I, with the nearest flanking AFLP markers 0.6 and 9.4 cM apart. This rare alkaloid was present in the foliage and not detected in potato tubers. Its presence in leaves did not affect resistance/susceptibility to Colorado potato beetle. 2011-02 2017-10-20T10:27:55Z 2017-10-20T10:27:55Z Journal Article https://hdl.handle.net/10568/89078 en Limited Access Springer Sagredo, B., Lorenzen, J., Casper, H. & Lafta, A. (2011). Linkage analysis of a rare alkaloid present in a tetraploid potato with Solanum chacoense background. Theoretical and Applied Genetics, 122(3), 471-478.
spellingShingle potato
genotypes
solanum chacoense
alkaloid
tetraploid potato
Sagredo, B.
Lorenzen, J.H.
Casper, H.
Lafta, A.
Linkage analysis of a rare alkaloid present in a tetraploid potato with Solanum chacoense background
title Linkage analysis of a rare alkaloid present in a tetraploid potato with Solanum chacoense background
title_full Linkage analysis of a rare alkaloid present in a tetraploid potato with Solanum chacoense background
title_fullStr Linkage analysis of a rare alkaloid present in a tetraploid potato with Solanum chacoense background
title_full_unstemmed Linkage analysis of a rare alkaloid present in a tetraploid potato with Solanum chacoense background
title_short Linkage analysis of a rare alkaloid present in a tetraploid potato with Solanum chacoense background
title_sort linkage analysis of a rare alkaloid present in a tetraploid potato with solanum chacoense background
topic potato
genotypes
solanum chacoense
alkaloid
tetraploid potato
url https://hdl.handle.net/10568/89078
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