QTL associated with resistance to cassava brown streak and cassava mosaic diseases in a bi-parental cross of two Tanzanian farmer varieties, Namikonga and Albert

Cassava production in Africa is compromised by cassava brown streak disease (CBSD) and cassava mosaic disease (CMD). To reduce costs and increase the precision of resistance breeding, a QTL study was conducted to identify molecular markers linked to resistance against these diseases. A bi-parental F...

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Main Authors: Masumba, E.A., Kapinga, F., Mkamilo, G.S., Salum, K., Kulembeka, H.P., Rounsley, S., Bredeson, J.V., Lyons, J.B., Rokhsar, D.S., Kanju, E., Katari, M.S., Myburg, A.A., Merwe, N.A. van der, Ferguson, Morag E.
Format: Journal Article
Language:Inglés
Published: Springer 2017
Subjects:
Online Access:https://hdl.handle.net/10568/82972
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author Masumba, E.A.
Kapinga, F.
Mkamilo, G.S.
Salum, K.
Kulembeka, H.P.
Rounsley, S.
Bredeson, J.V.
Lyons, J.B.
Rokhsar, D.S.
Kanju, E.
Katari, M.S.
Myburg, A.A.
Merwe, N.A. van der
Ferguson, Morag E.
author_browse Bredeson, J.V.
Ferguson, Morag E.
Kanju, E.
Kapinga, F.
Katari, M.S.
Kulembeka, H.P.
Lyons, J.B.
Masumba, E.A.
Merwe, N.A. van der
Mkamilo, G.S.
Myburg, A.A.
Rokhsar, D.S.
Rounsley, S.
Salum, K.
author_facet Masumba, E.A.
Kapinga, F.
Mkamilo, G.S.
Salum, K.
Kulembeka, H.P.
Rounsley, S.
Bredeson, J.V.
Lyons, J.B.
Rokhsar, D.S.
Kanju, E.
Katari, M.S.
Myburg, A.A.
Merwe, N.A. van der
Ferguson, Morag E.
author_sort Masumba, E.A.
collection Repository of Agricultural Research Outputs (CGSpace)
description Cassava production in Africa is compromised by cassava brown streak disease (CBSD) and cassava mosaic disease (CMD). To reduce costs and increase the precision of resistance breeding, a QTL study was conducted to identify molecular markers linked to resistance against these diseases. A bi-parental F1 mapping population was developed from a cross between the Tanzanian farmer varieties, Namikonga and Albert. A one-step genetic linkage map comprising 943 SNP markers and 18 linkage groups spanning 1776.2 cM was generated. Phenotypic data from 240 F1 progeny were obtained from two disease hotspots in Tanzania, over two successive seasons, 2013 and 2014. Two consistent QTLs linked to resistance to CBSD-induced root necrosis were identified in Namikonga on chromosomes II (qCBSDRNFc2Nm) and XI (qCBSDRNc11Nm) and a putative QTL on chromosome XVIII (qCBSDRNc18Nm). qCBSDRNFc2Nm was identified at Naliendele in both seasons. The same QTL was also associated with CBSD foliar resistance. qCBSDRNc11Nm was identified at Chambezi in both seasons, and was characterized by three peaks, spanning a distance of 253 kb. Twenty-seven genes were identified within this region including two LRR proteins and a signal recognition particle. In addition, two highly significant CMD resistance QTL (qCMDc12.1A and qCMDc12.2A) were detected in Albert, on chromosome 12. Both qCMDc12.1A and qCMDc12.2A lay within the range of markers reported earlier, defining the CMD2 locus. This is the first time that two loci have been identified within the CMD2 QTL, and in germplasm of apparent East African origin. Additional QTLs with minor effects on CBSD and CMD resistance were also identified.
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spelling CGSpace829722025-11-11T10:31:12Z QTL associated with resistance to cassava brown streak and cassava mosaic diseases in a bi-parental cross of two Tanzanian farmer varieties, Namikonga and Albert Masumba, E.A. Kapinga, F. Mkamilo, G.S. Salum, K. Kulembeka, H.P. Rounsley, S. Bredeson, J.V. Lyons, J.B. Rokhsar, D.S. Kanju, E. Katari, M.S. Myburg, A.A. Merwe, N.A. van der Ferguson, Morag E. cassava pollination molecular markers qtl cassava brown streak disease african cassava mosaic virus disease resistance Cassava production in Africa is compromised by cassava brown streak disease (CBSD) and cassava mosaic disease (CMD). To reduce costs and increase the precision of resistance breeding, a QTL study was conducted to identify molecular markers linked to resistance against these diseases. A bi-parental F1 mapping population was developed from a cross between the Tanzanian farmer varieties, Namikonga and Albert. A one-step genetic linkage map comprising 943 SNP markers and 18 linkage groups spanning 1776.2 cM was generated. Phenotypic data from 240 F1 progeny were obtained from two disease hotspots in Tanzania, over two successive seasons, 2013 and 2014. Two consistent QTLs linked to resistance to CBSD-induced root necrosis were identified in Namikonga on chromosomes II (qCBSDRNFc2Nm) and XI (qCBSDRNc11Nm) and a putative QTL on chromosome XVIII (qCBSDRNc18Nm). qCBSDRNFc2Nm was identified at Naliendele in both seasons. The same QTL was also associated with CBSD foliar resistance. qCBSDRNc11Nm was identified at Chambezi in both seasons, and was characterized by three peaks, spanning a distance of 253 kb. Twenty-seven genes were identified within this region including two LRR proteins and a signal recognition particle. In addition, two highly significant CMD resistance QTL (qCMDc12.1A and qCMDc12.2A) were detected in Albert, on chromosome 12. Both qCMDc12.1A and qCMDc12.2A lay within the range of markers reported earlier, defining the CMD2 locus. This is the first time that two loci have been identified within the CMD2 QTL, and in germplasm of apparent East African origin. Additional QTLs with minor effects on CBSD and CMD resistance were also identified. 2017-10 2017-08-01T11:29:00Z 2017-08-01T11:29:00Z Journal Article https://hdl.handle.net/10568/82972 en Open Access application/pdf Springer Masumba, E.A., Kapinga, F., Mkamilo, G., Salum, K., Kulembeka, H., Rounsley, S. ... & Katari, M.S. (2017). QTL associated with resistance to cassava brown streak and cassava mosaic diseases in a bi-parental cross of two Tanzanian farmer varieties, Namikonga and Albert. Theoretical and Applied Genetics, 1-22.
spellingShingle cassava
pollination
molecular markers
qtl
cassava brown streak disease
african cassava mosaic virus
disease resistance
Masumba, E.A.
Kapinga, F.
Mkamilo, G.S.
Salum, K.
Kulembeka, H.P.
Rounsley, S.
Bredeson, J.V.
Lyons, J.B.
Rokhsar, D.S.
Kanju, E.
Katari, M.S.
Myburg, A.A.
Merwe, N.A. van der
Ferguson, Morag E.
QTL associated with resistance to cassava brown streak and cassava mosaic diseases in a bi-parental cross of two Tanzanian farmer varieties, Namikonga and Albert
title QTL associated with resistance to cassava brown streak and cassava mosaic diseases in a bi-parental cross of two Tanzanian farmer varieties, Namikonga and Albert
title_full QTL associated with resistance to cassava brown streak and cassava mosaic diseases in a bi-parental cross of two Tanzanian farmer varieties, Namikonga and Albert
title_fullStr QTL associated with resistance to cassava brown streak and cassava mosaic diseases in a bi-parental cross of two Tanzanian farmer varieties, Namikonga and Albert
title_full_unstemmed QTL associated with resistance to cassava brown streak and cassava mosaic diseases in a bi-parental cross of two Tanzanian farmer varieties, Namikonga and Albert
title_short QTL associated with resistance to cassava brown streak and cassava mosaic diseases in a bi-parental cross of two Tanzanian farmer varieties, Namikonga and Albert
title_sort qtl associated with resistance to cassava brown streak and cassava mosaic diseases in a bi parental cross of two tanzanian farmer varieties namikonga and albert
topic cassava
pollination
molecular markers
qtl
cassava brown streak disease
african cassava mosaic virus
disease resistance
url https://hdl.handle.net/10568/82972
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