High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus)

Heteroplasmy is the presence of more than one mitochondrial DNA (mtDNA) variant within a cell, tissue, or individual. In this study, sequence variation was investigated in the control region (CR) of mitochondrial DNA (mtDNA) from 135 individuals belonging to five primary domestic Bactrian camel bree...

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Main Authors: Xiaohong He, Xiaofei Chen, Wenbin Zhang, Yabin Pu, Shen Song, Han Jianlin, Kunzhe Dong, Qian-Jun Zhao, Weijun, Guan, Yuehui Ma, Lin Jiang
Format: Journal Article
Language:Inglés
Published: Informa UK Limited 2017
Subjects:
Online Access:https://hdl.handle.net/10568/82809
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author Xiaohong He
Xiaofei Chen
Wenbin Zhang
Yabin Pu
Shen Song
Han Jianlin
Kunzhe Dong
Qian-Jun Zhao
Weijun, Guan
Yuehui Ma
Lin Jiang
author_browse Han Jianlin
Kunzhe Dong
Lin Jiang
Qian-Jun Zhao
Shen Song
Weijun, Guan
Wenbin Zhang
Xiaofei Chen
Xiaohong He
Yabin Pu
Yuehui Ma
author_facet Xiaohong He
Xiaofei Chen
Wenbin Zhang
Yabin Pu
Shen Song
Han Jianlin
Kunzhe Dong
Qian-Jun Zhao
Weijun, Guan
Yuehui Ma
Lin Jiang
author_sort Xiaohong He
collection Repository of Agricultural Research Outputs (CGSpace)
description Heteroplasmy is the presence of more than one mitochondrial DNA (mtDNA) variant within a cell, tissue, or individual. In this study, sequence variation was investigated in the control region (CR) of mitochondrial DNA (mtDNA) from 135 individuals belonging to five primary domestic Bactrian camel breeds in China and Mongolia. Due to variation of the repeat unit G(T/C)(AC)n, length heteroplasmy was detected within each camel by direct sequencing and fragment analysis. A high occurrence of mtDNA heteroplasmy, up to 100 percentages was observed in five camel populations. Our study provides the first evidence of extensive length heteroplasmy in Bactrian camels.
format Journal Article
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institution CGIAR Consortium
language Inglés
publishDate 2017
publishDateRange 2017
publishDateSort 2017
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publisherStr Informa UK Limited
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spelling CGSpace828092023-03-18T05:01:01Z High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus) Xiaohong He Xiaofei Chen Wenbin Zhang Yabin Pu Shen Song Han Jianlin Kunzhe Dong Qian-Jun Zhao Weijun, Guan Yuehui Ma Lin Jiang animal breeding camels genetics Heteroplasmy is the presence of more than one mitochondrial DNA (mtDNA) variant within a cell, tissue, or individual. In this study, sequence variation was investigated in the control region (CR) of mitochondrial DNA (mtDNA) from 135 individuals belonging to five primary domestic Bactrian camel breeds in China and Mongolia. Due to variation of the repeat unit G(T/C)(AC)n, length heteroplasmy was detected within each camel by direct sequencing and fragment analysis. A high occurrence of mtDNA heteroplasmy, up to 100 percentages was observed in five camel populations. Our study provides the first evidence of extensive length heteroplasmy in Bactrian camels. 2017-11-02 2017-07-18T08:24:09Z 2017-07-18T08:24:09Z Journal Article https://hdl.handle.net/10568/82809 en Limited Access Informa UK Limited Xiaohong He, Xiaofei Chen, Wenbin Zhang, Yabin Pu, Shen Song, Jianlin Han, Kunzhe Dong, Qianjun Zhao, Weijun Guan, Yuehui Ma and Lin Jiang. 2017. High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus). Mitochondrial DNA Part A. 28(6):851-854.
spellingShingle animal breeding
camels
genetics
Xiaohong He
Xiaofei Chen
Wenbin Zhang
Yabin Pu
Shen Song
Han Jianlin
Kunzhe Dong
Qian-Jun Zhao
Weijun, Guan
Yuehui Ma
Lin Jiang
High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus)
title High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus)
title_full High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus)
title_fullStr High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus)
title_full_unstemmed High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus)
title_short High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus)
title_sort high occurrence of length heteroplasmy in domestic bactrian camel camelus bactrianus
topic animal breeding
camels
genetics
url https://hdl.handle.net/10568/82809
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