Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015

Tularemia is a highly contagious infectious zoonosis caused by the bacterial agent Francisella tularensis. The aim of this study was to investigate the presence of antibodies to Francisella tularensis in febrile patients in northeastern Kenya. During 2014-2015, 730 patients were screened for anti-Fr...

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Autores principales: Njeru, J., Tomaso, H., Mertens, K., Henning, K., Wareth, G., Heller, R., Kariuki, S., Fèvre, Eric M., Neubauer, H., Pletz, M.W.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://hdl.handle.net/10568/81518
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author Njeru, J.
Tomaso, H.
Mertens, K.
Henning, K.
Wareth, G.
Heller, R.
Kariuki, S.
Fèvre, Eric M.
Neubauer, H.
Pletz, M.W.
author_browse Fèvre, Eric M.
Heller, R.
Henning, K.
Kariuki, S.
Mertens, K.
Neubauer, H.
Njeru, J.
Pletz, M.W.
Tomaso, H.
Wareth, G.
author_facet Njeru, J.
Tomaso, H.
Mertens, K.
Henning, K.
Wareth, G.
Heller, R.
Kariuki, S.
Fèvre, Eric M.
Neubauer, H.
Pletz, M.W.
author_sort Njeru, J.
collection Repository of Agricultural Research Outputs (CGSpace)
description Tularemia is a highly contagious infectious zoonosis caused by the bacterial agent Francisella tularensis. The aim of this study was to investigate the presence of antibodies to Francisella tularensis in febrile patients in northeastern Kenya. During 2014-2015, 730 patients were screened for anti-Francisella tularensis antibodies using a combination of ELISA and western blot (WB). Twenty seven (3.7%) patients were positive for F. tularensis. Tularemia was not suspected by the treating clinicians in any of those patients. Our results suggest that tularemia may be present in Kenya but remain unreported, and emphasizes the need for local clinicians to broaden their diagnostic repertoire when evaluating patients with undifferentiated febrile illness.
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spelling CGSpace815182025-12-08T09:54:28Z Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015 Njeru, J. Tomaso, H. Mertens, K. Henning, K. Wareth, G. Heller, R. Kariuki, S. Fèvre, Eric M. Neubauer, H. Pletz, M.W. animal diseases health zoonoses Tularemia is a highly contagious infectious zoonosis caused by the bacterial agent Francisella tularensis. The aim of this study was to investigate the presence of antibodies to Francisella tularensis in febrile patients in northeastern Kenya. During 2014-2015, 730 patients were screened for anti-Francisella tularensis antibodies using a combination of ELISA and western blot (WB). Twenty seven (3.7%) patients were positive for F. tularensis. Tularemia was not suspected by the treating clinicians in any of those patients. Our results suggest that tularemia may be present in Kenya but remain unreported, and emphasizes the need for local clinicians to broaden their diagnostic repertoire when evaluating patients with undifferentiated febrile illness. 2017-09 2017-06-12T07:28:56Z 2017-06-12T07:28:56Z Journal Article https://hdl.handle.net/10568/81518 en Open Access Elsevier Njeru, J., Tomaso, H., Mertens, K., Henning, K., Wareth, G., Heller, R., Kariuki, S., Fèvre, E.M., Neubauer, H. and Pletz, M.W. 2017. Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015. New Microbes and New Infections 19: 62–66.
spellingShingle animal diseases
health
zoonoses
Njeru, J.
Tomaso, H.
Mertens, K.
Henning, K.
Wareth, G.
Heller, R.
Kariuki, S.
Fèvre, Eric M.
Neubauer, H.
Pletz, M.W.
Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015
title Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015
title_full Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015
title_fullStr Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015
title_full_unstemmed Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015
title_short Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015
title_sort serological evidence of francisella tularensis in febrile patients seeking treatment at remote hospitals northeastern kenya 2014 2015
topic animal diseases
health
zoonoses
url https://hdl.handle.net/10568/81518
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