Sero-prevalence of specific Leptospira serovars in fattening pigs from 5 provinces in Vietnam

Background Leptospirosis is a zoonotic bacterial disease with a worldwide distribution. In Vietnam, leptospirosis is considered endemic. In pigs, leptospirosis can result in reproductive problems (such as abortion and infertility) which lead to economic loss. In addition, transmission to people pres...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu Suk Lee, Nguyen Viet Khong, Huyen Nguyen Xuan, Vuong Bui Nghia, Hung Nguyen-Viet, Grace, Delia
Formato: Journal Article
Lenguaje:Inglés
Publicado: Springer 2017
Materias:
Acceso en línea:https://hdl.handle.net/10568/81105
_version_ 1855527722974969856
author Hu Suk Lee
Nguyen Viet Khong
Huyen Nguyen Xuan
Vuong Bui Nghia
Hung Nguyen-Viet
Grace, Delia
author_browse Grace, Delia
Hu Suk Lee
Hung Nguyen-Viet
Huyen Nguyen Xuan
Nguyen Viet Khong
Vuong Bui Nghia
author_facet Hu Suk Lee
Nguyen Viet Khong
Huyen Nguyen Xuan
Vuong Bui Nghia
Hung Nguyen-Viet
Grace, Delia
author_sort Hu Suk Lee
collection Repository of Agricultural Research Outputs (CGSpace)
description Background Leptospirosis is a zoonotic bacterial disease with a worldwide distribution. In Vietnam, leptospirosis is considered endemic. In pigs, leptospirosis can result in reproductive problems (such as abortion and infertility) which lead to economic loss. In addition, transmission to people presents a public health risk. In Vietnam, few national studies have been conducted on sero-prevalence of leptospirosis in pigs. The main objective of this study was to evaluate the sero-prevalence and incidence of presumptive infective leptospira serovars in fattening pigs from 5 provinces in Vietnam. Results Blood samples from fattening pigs were randomly collected at slaughterhouses. We collected 1959 sera samples from 5 provinces (Son La, Hanoi, Nghe An, Dak Lak and An Giang) between January and early June 2016. The microscopic agglutination test (MAT) was used to identify the serogroups/serovars. Overall, the sero-prevalence was 8.17% (95% CI: 6.99–9.47) and serovar Tarassovi Mitis (2.19%) had the highest prevalence followed by Australis (1.94%), Javanica (1.68%) and Autumnalis (1.17%) using a cutoff (≥ 1:100). The sero-prevalence among female pigs (5.28%, 95% CI: 3.94–6.93) was slightly higher than among male pigs (4.88%, 95% CI: 3.51–6.58), but this difference was not statistically significant. Conclusions Leptospirosis in pigs may be a useful indicator of the human/animal burden in Vietnam and a risk assessment tool. The presence of some of the identified serovars suggests that wildlife may play an important role in the transmission of leptospirosis to domesticated pigs in Vietnam. Therefore, strengthened monitoring and surveillance systems are needed to better understand the epidemiology of the disease and prevent or reduce infection in humans and animals.
format Journal Article
id CGSpace81105
institution CGIAR Consortium
language Inglés
publishDate 2017
publishDateRange 2017
publishDateSort 2017
publisher Springer
publisherStr Springer
record_format dspace
spelling CGSpace811052024-05-01T08:17:48Z Sero-prevalence of specific Leptospira serovars in fattening pigs from 5 provinces in Vietnam Hu Suk Lee Nguyen Viet Khong Huyen Nguyen Xuan Vuong Bui Nghia Hung Nguyen-Viet Grace, Delia animal diseases swine zoonoses Background Leptospirosis is a zoonotic bacterial disease with a worldwide distribution. In Vietnam, leptospirosis is considered endemic. In pigs, leptospirosis can result in reproductive problems (such as abortion and infertility) which lead to economic loss. In addition, transmission to people presents a public health risk. In Vietnam, few national studies have been conducted on sero-prevalence of leptospirosis in pigs. The main objective of this study was to evaluate the sero-prevalence and incidence of presumptive infective leptospira serovars in fattening pigs from 5 provinces in Vietnam. Results Blood samples from fattening pigs were randomly collected at slaughterhouses. We collected 1959 sera samples from 5 provinces (Son La, Hanoi, Nghe An, Dak Lak and An Giang) between January and early June 2016. The microscopic agglutination test (MAT) was used to identify the serogroups/serovars. Overall, the sero-prevalence was 8.17% (95% CI: 6.99–9.47) and serovar Tarassovi Mitis (2.19%) had the highest prevalence followed by Australis (1.94%), Javanica (1.68%) and Autumnalis (1.17%) using a cutoff (≥ 1:100). The sero-prevalence among female pigs (5.28%, 95% CI: 3.94–6.93) was slightly higher than among male pigs (4.88%, 95% CI: 3.51–6.58), but this difference was not statistically significant. Conclusions Leptospirosis in pigs may be a useful indicator of the human/animal burden in Vietnam and a risk assessment tool. The presence of some of the identified serovars suggests that wildlife may play an important role in the transmission of leptospirosis to domesticated pigs in Vietnam. Therefore, strengthened monitoring and surveillance systems are needed to better understand the epidemiology of the disease and prevent or reduce infection in humans and animals. 2017-12 2017-05-17T08:16:34Z 2017-05-17T08:16:34Z Journal Article https://hdl.handle.net/10568/81105 en Open Access Springer Hu Suk Lee, Nguyen Viet Khong, Huyen Nguyen Xuan, Vuong Bui Nghia, Hung Nguyen-Viet and Grace, D. 2017. Sero-prevalence of specific Leptospira serovars in fattening pigs from 5 provinces in Vietnam. BMC Veterinary Research 13: 125.
spellingShingle animal diseases
swine
zoonoses
Hu Suk Lee
Nguyen Viet Khong
Huyen Nguyen Xuan
Vuong Bui Nghia
Hung Nguyen-Viet
Grace, Delia
Sero-prevalence of specific Leptospira serovars in fattening pigs from 5 provinces in Vietnam
title Sero-prevalence of specific Leptospira serovars in fattening pigs from 5 provinces in Vietnam
title_full Sero-prevalence of specific Leptospira serovars in fattening pigs from 5 provinces in Vietnam
title_fullStr Sero-prevalence of specific Leptospira serovars in fattening pigs from 5 provinces in Vietnam
title_full_unstemmed Sero-prevalence of specific Leptospira serovars in fattening pigs from 5 provinces in Vietnam
title_short Sero-prevalence of specific Leptospira serovars in fattening pigs from 5 provinces in Vietnam
title_sort sero prevalence of specific leptospira serovars in fattening pigs from 5 provinces in vietnam
topic animal diseases
swine
zoonoses
url https://hdl.handle.net/10568/81105
work_keys_str_mv AT husuklee seroprevalenceofspecificleptospiraserovarsinfatteningpigsfrom5provincesinvietnam
AT nguyenvietkhong seroprevalenceofspecificleptospiraserovarsinfatteningpigsfrom5provincesinvietnam
AT huyennguyenxuan seroprevalenceofspecificleptospiraserovarsinfatteningpigsfrom5provincesinvietnam
AT vuongbuinghia seroprevalenceofspecificleptospiraserovarsinfatteningpigsfrom5provincesinvietnam
AT hungnguyenviet seroprevalenceofspecificleptospiraserovarsinfatteningpigsfrom5provincesinvietnam
AT gracedelia seroprevalenceofspecificleptospiraserovarsinfatteningpigsfrom5provincesinvietnam