The genome landscape of indigenous African cattle
Background: The history of African indigenous cattle and their adaptation to environmental and human selection pressure is at the root of their remarkable diversity. Characterization of this diversity is an essential step towards understanding the genomic basis of productivity and adaptation to surv...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Springer
2017
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/80008 |
| _version_ | 1855516250844692480 |
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| author | Kim, Jaemin Hanotte, Olivier H. Okeyo Mwai, Ally Dessie, Tadelle Salim, Bashir Diallo, Boubacar Agaba, Morris Kwondo Kim Woori Kwak Samsun Sung Seo, Minseok Jeong, Hyeonsoo Kwon, Taehyung Taye, Mengistie Song, Ki-Duk Lim, Dajeong Seoae Cho Lee, Hyun-Jeong Duhak Yoon Sung Jong Oh Kemp, Stephen J. Hak-Kyo Lee Heebal Kim |
| author_browse | Agaba, Morris Dessie, Tadelle Diallo, Boubacar Duhak Yoon Hak-Kyo Lee Hanotte, Olivier H. Heebal Kim Jeong, Hyeonsoo Kemp, Stephen J. Kim, Jaemin Kwon, Taehyung Kwondo Kim Lee, Hyun-Jeong Lim, Dajeong Okeyo Mwai, Ally Salim, Bashir Samsun Sung Seo, Minseok Seoae Cho Song, Ki-Duk Sung Jong Oh Taye, Mengistie Woori Kwak |
| author_facet | Kim, Jaemin Hanotte, Olivier H. Okeyo Mwai, Ally Dessie, Tadelle Salim, Bashir Diallo, Boubacar Agaba, Morris Kwondo Kim Woori Kwak Samsun Sung Seo, Minseok Jeong, Hyeonsoo Kwon, Taehyung Taye, Mengistie Song, Ki-Duk Lim, Dajeong Seoae Cho Lee, Hyun-Jeong Duhak Yoon Sung Jong Oh Kemp, Stephen J. Hak-Kyo Lee Heebal Kim |
| author_sort | Kim, Jaemin |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Background: The history of African indigenous cattle and their adaptation to environmental and human selection pressure is at the root of their remarkable diversity. Characterization of this diversity is an essential step towards understanding the genomic basis of productivity and adaptation to survival under African farming systems. Results: We analyze patterns of African cattle genetic variation by sequencing 48 genomes from five indigenous populations and comparing them to the genomes of 53 commercial taurine breeds. We find the highest genetic diversity among African zebu and sanga cattle. Our search for genomic regions under selection reveals signatures of selection for environmental adaptive traits. In particular, we identify signatures of selection including genes and/ or pathways controlling anemia and feeding behavior in the trypanotolerant N’Dama, coat color and horn development in Ankole, and heat tolerance and tick resistance across African cattle especially in zebu breeds. Conclusions: Our findings unravel at the genome-wide level, the unique adaptive diversity of African cattle while emphasizing the opportunities for sustainable improvement of livestock productivity on the continent. |
| format | Journal Article |
| id | CGSpace80008 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | CGSpace800082023-12-08T19:36:04Z The genome landscape of indigenous African cattle Kim, Jaemin Hanotte, Olivier H. Okeyo Mwai, Ally Dessie, Tadelle Salim, Bashir Diallo, Boubacar Agaba, Morris Kwondo Kim Woori Kwak Samsun Sung Seo, Minseok Jeong, Hyeonsoo Kwon, Taehyung Taye, Mengistie Song, Ki-Duk Lim, Dajeong Seoae Cho Lee, Hyun-Jeong Duhak Yoon Sung Jong Oh Kemp, Stephen J. Hak-Kyo Lee Heebal Kim indigenous breeds breeds animal breeding livestock cattle genomes adaptation Background: The history of African indigenous cattle and their adaptation to environmental and human selection pressure is at the root of their remarkable diversity. Characterization of this diversity is an essential step towards understanding the genomic basis of productivity and adaptation to survival under African farming systems. Results: We analyze patterns of African cattle genetic variation by sequencing 48 genomes from five indigenous populations and comparing them to the genomes of 53 commercial taurine breeds. We find the highest genetic diversity among African zebu and sanga cattle. Our search for genomic regions under selection reveals signatures of selection for environmental adaptive traits. In particular, we identify signatures of selection including genes and/ or pathways controlling anemia and feeding behavior in the trypanotolerant N’Dama, coat color and horn development in Ankole, and heat tolerance and tick resistance across African cattle especially in zebu breeds. Conclusions: Our findings unravel at the genome-wide level, the unique adaptive diversity of African cattle while emphasizing the opportunities for sustainable improvement of livestock productivity on the continent. 2017-12 2017-02-23T09:29:45Z 2017-02-23T09:29:45Z Journal Article https://hdl.handle.net/10568/80008 en Open Access Springer Kim, J., Hanotte, O., Mwai, O.A., Dessie, T., Bashir, S., Diallo, B., Agaba, M., Kim, K., Kwak, W., Sung, S., Seo, M., Jeong, H., Kwon, T., Taye, M., Ki-Duk Song, Dajeong Lim, Seoae Cho, Hyun-Jeong Lee, Duhak Yoon, Sung Jong Oh, Kemp, S., Hak-Kyo Lee and Heebal Kim. 2017. The genome landscape of indigenous African cattle. Genome Biology 18:34 |
| spellingShingle | indigenous breeds breeds animal breeding livestock cattle genomes adaptation Kim, Jaemin Hanotte, Olivier H. Okeyo Mwai, Ally Dessie, Tadelle Salim, Bashir Diallo, Boubacar Agaba, Morris Kwondo Kim Woori Kwak Samsun Sung Seo, Minseok Jeong, Hyeonsoo Kwon, Taehyung Taye, Mengistie Song, Ki-Duk Lim, Dajeong Seoae Cho Lee, Hyun-Jeong Duhak Yoon Sung Jong Oh Kemp, Stephen J. Hak-Kyo Lee Heebal Kim The genome landscape of indigenous African cattle |
| title | The genome landscape of indigenous African cattle |
| title_full | The genome landscape of indigenous African cattle |
| title_fullStr | The genome landscape of indigenous African cattle |
| title_full_unstemmed | The genome landscape of indigenous African cattle |
| title_short | The genome landscape of indigenous African cattle |
| title_sort | genome landscape of indigenous african cattle |
| topic | indigenous breeds breeds animal breeding livestock cattle genomes adaptation |
| url | https://hdl.handle.net/10568/80008 |
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