Modelling the risk of Taenia solium exposure from pork produced in western Kenya
The tapeworm Taenia solium is the parasite responsible for neurocysticercosis, a neglected tropical disease of public health importance, thought to cause approximately 1/3 of epilepsy cases across endemic regions. The consumption of undercooked infected pork perpetuates the parasite’s life-cycle thr...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Public Library of Science
2017
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/79991 |
| _version_ | 1855516212878901248 |
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| author | Thomas, Lian F. Glanville, William A. de Cook, Elizabeth A.J. Bronsvoort, B.M. de C. Handel, Ian G. Wamae, C.N. Kariuki, S. Fèvre, Eric M. |
| author_browse | Bronsvoort, B.M. de C. Cook, Elizabeth A.J. Fèvre, Eric M. Glanville, William A. de Handel, Ian G. Kariuki, S. Thomas, Lian F. Wamae, C.N. |
| author_facet | Thomas, Lian F. Glanville, William A. de Cook, Elizabeth A.J. Bronsvoort, B.M. de C. Handel, Ian G. Wamae, C.N. Kariuki, S. Fèvre, Eric M. |
| author_sort | Thomas, Lian F. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | The tapeworm Taenia solium is the parasite responsible for neurocysticercosis, a neglected tropical disease of public health importance, thought to cause approximately 1/3 of epilepsy cases across endemic regions. The consumption of undercooked infected pork perpetuates the parasite’s life-cycle through the establishment of adult tapeworm infections in the community. Reducing the risk associated with pork consumption in the developing world is therefore a public health priority. The aim of this study was to estimate the risk of any one pork meal in western Kenya containing a potentially infective T. solium cysticercus at the point of consumption, an aspect of the parasite transmission that has not been estimated before. To estimate this, we used a quantitative food chain risk assessment model built in the @RISK add-on to Microsoft Excel. This model indicates that any one pork meal consumed in western Kenya has a 0.006 (99% Uncertainty Interval (U.I). 0.0002–0.0164) probability of containing at least one viable T. solium cysticercus at the point of consumption and therefore being potentially infectious to humans. This equates to 22,282 (99% U.I. 622–64,134) potentially infective pork meals consumed in the course of one year within Busia District alone. This model indicates a high risk of T. solium infection associated with pork consumption in western Kenya and the work presented here can be built upon to investigate the efficacy of various mitigation strategies for this locality. |
| format | Journal Article |
| id | CGSpace79991 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Public Library of Science |
| publisherStr | Public Library of Science |
| record_format | dspace |
| spelling | CGSpace799912024-01-17T12:58:34Z Modelling the risk of Taenia solium exposure from pork produced in western Kenya Thomas, Lian F. Glanville, William A. de Cook, Elizabeth A.J. Bronsvoort, B.M. de C. Handel, Ian G. Wamae, C.N. Kariuki, S. Fèvre, Eric M. animal diseases food safety infectious diseases The tapeworm Taenia solium is the parasite responsible for neurocysticercosis, a neglected tropical disease of public health importance, thought to cause approximately 1/3 of epilepsy cases across endemic regions. The consumption of undercooked infected pork perpetuates the parasite’s life-cycle through the establishment of adult tapeworm infections in the community. Reducing the risk associated with pork consumption in the developing world is therefore a public health priority. The aim of this study was to estimate the risk of any one pork meal in western Kenya containing a potentially infective T. solium cysticercus at the point of consumption, an aspect of the parasite transmission that has not been estimated before. To estimate this, we used a quantitative food chain risk assessment model built in the @RISK add-on to Microsoft Excel. This model indicates that any one pork meal consumed in western Kenya has a 0.006 (99% Uncertainty Interval (U.I). 0.0002–0.0164) probability of containing at least one viable T. solium cysticercus at the point of consumption and therefore being potentially infectious to humans. This equates to 22,282 (99% U.I. 622–64,134) potentially infective pork meals consumed in the course of one year within Busia District alone. This model indicates a high risk of T. solium infection associated with pork consumption in western Kenya and the work presented here can be built upon to investigate the efficacy of various mitigation strategies for this locality. 2017-02-17 2017-02-23T09:19:03Z 2017-02-23T09:19:03Z Journal Article https://hdl.handle.net/10568/79991 en Open Access Public Library of Science Thomas, L.F., Glanville, W.A. de, Cook, E.A.J., Bronsvoort, B.M. de C., Handel, I., Wamae, C.N., Kariuki, S. and Fèvre, E.M. 2017. Modelling the risk of Taenia solium exposure from pork produced in western Kenya. PLOS Neglected Tropical Diseases 11(2): e0005371. |
| spellingShingle | animal diseases food safety infectious diseases Thomas, Lian F. Glanville, William A. de Cook, Elizabeth A.J. Bronsvoort, B.M. de C. Handel, Ian G. Wamae, C.N. Kariuki, S. Fèvre, Eric M. Modelling the risk of Taenia solium exposure from pork produced in western Kenya |
| title | Modelling the risk of Taenia solium exposure from pork produced in western Kenya |
| title_full | Modelling the risk of Taenia solium exposure from pork produced in western Kenya |
| title_fullStr | Modelling the risk of Taenia solium exposure from pork produced in western Kenya |
| title_full_unstemmed | Modelling the risk of Taenia solium exposure from pork produced in western Kenya |
| title_short | Modelling the risk of Taenia solium exposure from pork produced in western Kenya |
| title_sort | modelling the risk of taenia solium exposure from pork produced in western kenya |
| topic | animal diseases food safety infectious diseases |
| url | https://hdl.handle.net/10568/79991 |
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