Replacing two conserved amino acids, (Asn-52 to Val and Try-67 to phe), in the Iso-1-cytochrome c gene has little effect on the function of the protein.
Tyr-67 and Asn-52 are among the conserved residues in the amino acid sequence of eukaryotic cytochromes c. These residues, together with Thr-78 are hydrogen bonded to a buried water molecule, (Wat-l66), which is also a conserved structural feature in all naturally occuring eukaryotic cytochromes c w...
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| Format: | Tesis |
| Language: | Inglés |
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Concordia University
1994
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| Online Access: | https://hdl.handle.net/10568/79498 |