Public health benefits from livestock Rift Valley fever control: A simulation of two epidemics in Kenya
In controlling Rift Valley fever, public health sector optimises health benefits by considering cost-effective control options. We modelled cost-effectiveness of livestock RVF control from a public health perspective in Kenya. Analysis was limited to pastoral and agro-pastoral system high-risk areas...
| Autores principales: | , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Springer
2016
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/78108 |
| _version_ | 1855527390939185152 |
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| author | Kimani, T. Schelling, E. Bett, Bernard K. Ngigi, M. Randolph, Thomas F. Fuhrimann, S. |
| author_browse | Bett, Bernard K. Fuhrimann, S. Kimani, T. Ngigi, M. Randolph, Thomas F. Schelling, E. |
| author_facet | Kimani, T. Schelling, E. Bett, Bernard K. Ngigi, M. Randolph, Thomas F. Fuhrimann, S. |
| author_sort | Kimani, T. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | In controlling Rift Valley fever, public health sector optimises health benefits by considering cost-effective control options. We modelled cost-effectiveness of livestock RVF control from a public health perspective in Kenya. Analysis was limited to pastoral and agro-pastoral system high-risk areas, for a 10-year period incorporating two epidemics: 2006/2007 and a hypothetical one in 2014/2015. Four integrated strategies (baseline and alternatives), combined from three vaccination and two surveillance options, were compared. Baseline strategy included annual vaccination of 1.2–11% animals plus passive surveillance and monitoring of nine sentinel herds. Compared to the baseline, two alternatives assumed improved vaccination coverage. A herd dynamic RVF animal simulation model produced number of animals infected under each strategy. A second mathematical model implemented in R estimated number people who would be infected by the infected animals. The 2006/2007 RVF epidemic resulted in 3974 undiscounted, unweighted disability adjusted life years (DALYs). Improving vaccination coverage to 41–51% (2012) and 27–33% (2014) 3 years before the hypothetical 2014/2015 outbreak can avert close to 1200 DALYs. Improved vaccinations showed cost-effectiveness (CE) values of US$ 43–53 per DALY averted. The baseline practice is not cost-effective to the public health sector. |
| format | Journal Article |
| id | CGSpace78108 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2016 |
| publishDateRange | 2016 |
| publishDateSort | 2016 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | CGSpace781082023-12-08T19:36:04Z Public health benefits from livestock Rift Valley fever control: A simulation of two epidemics in Kenya Kimani, T. Schelling, E. Bett, Bernard K. Ngigi, M. Randolph, Thomas F. Fuhrimann, S. animal diseases epidemiology zoonoses health In controlling Rift Valley fever, public health sector optimises health benefits by considering cost-effective control options. We modelled cost-effectiveness of livestock RVF control from a public health perspective in Kenya. Analysis was limited to pastoral and agro-pastoral system high-risk areas, for a 10-year period incorporating two epidemics: 2006/2007 and a hypothetical one in 2014/2015. Four integrated strategies (baseline and alternatives), combined from three vaccination and two surveillance options, were compared. Baseline strategy included annual vaccination of 1.2–11% animals plus passive surveillance and monitoring of nine sentinel herds. Compared to the baseline, two alternatives assumed improved vaccination coverage. A herd dynamic RVF animal simulation model produced number of animals infected under each strategy. A second mathematical model implemented in R estimated number people who would be infected by the infected animals. The 2006/2007 RVF epidemic resulted in 3974 undiscounted, unweighted disability adjusted life years (DALYs). Improving vaccination coverage to 41–51% (2012) and 27–33% (2014) 3 years before the hypothetical 2014/2015 outbreak can avert close to 1200 DALYs. Improved vaccinations showed cost-effectiveness (CE) values of US$ 43–53 per DALY averted. The baseline practice is not cost-effective to the public health sector. 2016-12 2016-12-04T13:16:44Z 2016-12-04T13:16:44Z Journal Article https://hdl.handle.net/10568/78108 en Open Access Springer Kimani, T., Schelling, E., Bett, B., Ngigi, M., Randolph, T. and Fuhrimann, S. 2016. Public health benefits from livestock Rift Valley fever control: A simulation of two epidemics in Kenya. Ecohealth 13(4):729–742. |
| spellingShingle | animal diseases epidemiology zoonoses health Kimani, T. Schelling, E. Bett, Bernard K. Ngigi, M. Randolph, Thomas F. Fuhrimann, S. Public health benefits from livestock Rift Valley fever control: A simulation of two epidemics in Kenya |
| title | Public health benefits from livestock Rift Valley fever control: A simulation of two epidemics in Kenya |
| title_full | Public health benefits from livestock Rift Valley fever control: A simulation of two epidemics in Kenya |
| title_fullStr | Public health benefits from livestock Rift Valley fever control: A simulation of two epidemics in Kenya |
| title_full_unstemmed | Public health benefits from livestock Rift Valley fever control: A simulation of two epidemics in Kenya |
| title_short | Public health benefits from livestock Rift Valley fever control: A simulation of two epidemics in Kenya |
| title_sort | public health benefits from livestock rift valley fever control a simulation of two epidemics in kenya |
| topic | animal diseases epidemiology zoonoses health |
| url | https://hdl.handle.net/10568/78108 |
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