Marker-based estimates reveal significant non-additive effects in clonally propagated cassava (Manihot esculenta): implications for the prediction of total genetic value and the selection of varieties

In clonally propagated crops, non-additive genetic effects can be effectively exploited by the identification of superior genetic individuals as varieties. Cassava (Manihot esculenta Crantz) is a clonally propagated staple food crop that feeds hundreds of millions. We quantified the amount and natur...

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Main Authors: Wolfe, M.D., Kulakow, Peter A., Rabbi, Ismail Y., Jannink, Jean-Luc
Format: Journal Article
Language:Inglés
Published: Oxford University Press 2016
Subjects:
Online Access:https://hdl.handle.net/10568/77138
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author Wolfe, M.D.
Kulakow, Peter A.
Rabbi, Ismail Y.
Jannink, Jean-Luc
author_browse Jannink, Jean-Luc
Kulakow, Peter A.
Rabbi, Ismail Y.
Wolfe, M.D.
author_facet Wolfe, M.D.
Kulakow, Peter A.
Rabbi, Ismail Y.
Jannink, Jean-Luc
author_sort Wolfe, M.D.
collection Repository of Agricultural Research Outputs (CGSpace)
description In clonally propagated crops, non-additive genetic effects can be effectively exploited by the identification of superior genetic individuals as varieties. Cassava (Manihot esculenta Crantz) is a clonally propagated staple food crop that feeds hundreds of millions. We quantified the amount and nature of non-additive genetic variation for key traits in a breeding population of cassava from sub-Saharan Africa using additive and non-additive genome-wide marker-based relationship matrices. We then assessed the accuracy of genomic prediction of additive compared to total (additive plus non-additive) genetic value. We confirmed previous findings based on diallel populations, that non-additive genetic variation is significant, especially for yield traits. Further, we show that we total genetic value correlated more strongly to observed phenotypes than did additive value, although this is constrained by low broad-sense heritability and is not beneficial for traits with already high heritability. We address the implication of these results for cassava breeding and put our work in the context of previous results in cassava, and other plant and animal species.
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spelling CGSpace771382025-11-11T10:04:18Z Marker-based estimates reveal significant non-additive effects in clonally propagated cassava (Manihot esculenta): implications for the prediction of total genetic value and the selection of varieties Wolfe, M.D. Kulakow, Peter A. Rabbi, Ismail Y. Jannink, Jean-Luc cassava food crops genomic features genetics molecular biology In clonally propagated crops, non-additive genetic effects can be effectively exploited by the identification of superior genetic individuals as varieties. Cassava (Manihot esculenta Crantz) is a clonally propagated staple food crop that feeds hundreds of millions. We quantified the amount and nature of non-additive genetic variation for key traits in a breeding population of cassava from sub-Saharan Africa using additive and non-additive genome-wide marker-based relationship matrices. We then assessed the accuracy of genomic prediction of additive compared to total (additive plus non-additive) genetic value. We confirmed previous findings based on diallel populations, that non-additive genetic variation is significant, especially for yield traits. Further, we show that we total genetic value correlated more strongly to observed phenotypes than did additive value, although this is constrained by low broad-sense heritability and is not beneficial for traits with already high heritability. We address the implication of these results for cassava breeding and put our work in the context of previous results in cassava, and other plant and animal species. 2016-11-01 2016-09-27T11:11:37Z 2016-09-27T11:11:37Z Journal Article https://hdl.handle.net/10568/77138 en Open Access application/pdf Oxford University Press Wolfe, M.D., Kulakow, P., Rabbi, I. & Jannink, Jean-Luc. (2016). Marker-based estimates reveal significant non-additive effects in clonally propagated cassava (Manihot esculenta): implications for the prediction of total genetic value and the selection of varieties. G3-Genes Genomes Genetics, 1-41
spellingShingle cassava
food crops
genomic features
genetics
molecular biology
Wolfe, M.D.
Kulakow, Peter A.
Rabbi, Ismail Y.
Jannink, Jean-Luc
Marker-based estimates reveal significant non-additive effects in clonally propagated cassava (Manihot esculenta): implications for the prediction of total genetic value and the selection of varieties
title Marker-based estimates reveal significant non-additive effects in clonally propagated cassava (Manihot esculenta): implications for the prediction of total genetic value and the selection of varieties
title_full Marker-based estimates reveal significant non-additive effects in clonally propagated cassava (Manihot esculenta): implications for the prediction of total genetic value and the selection of varieties
title_fullStr Marker-based estimates reveal significant non-additive effects in clonally propagated cassava (Manihot esculenta): implications for the prediction of total genetic value and the selection of varieties
title_full_unstemmed Marker-based estimates reveal significant non-additive effects in clonally propagated cassava (Manihot esculenta): implications for the prediction of total genetic value and the selection of varieties
title_short Marker-based estimates reveal significant non-additive effects in clonally propagated cassava (Manihot esculenta): implications for the prediction of total genetic value and the selection of varieties
title_sort marker based estimates reveal significant non additive effects in clonally propagated cassava manihot esculenta implications for the prediction of total genetic value and the selection of varieties
topic cassava
food crops
genomic features
genetics
molecular biology
url https://hdl.handle.net/10568/77138
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