The global distribution of Crimean-Congo hemorrhagic fever
Background Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne infection caused by a virus (CCHFV) from the Bunyaviridae family. Domestic and wild vertebrates are asymptomatic reservoirs for the virus, putting animal handlers, slaughter-house workers and agricultural labourers at highest risk in...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
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Oxford University Press
2015
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/74301 |
| _version_ | 1855521526661513216 |
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| author | Messina, J.P. Pigott, D.M. Golding, N. Duda, K.A. Brownstein, J.S. Weiss, Daniel J. Gibson, H. Robinson, Timothy P. Gilbert, M. Wint, G.R.W. Nuttall, P.A. Gething, P.W. Myers, M.F. George, D.B. Hay, S.I. |
| author_browse | Brownstein, J.S. Duda, K.A. George, D.B. Gething, P.W. Gibson, H. Gilbert, M. Golding, N. Hay, S.I. Messina, J.P. Myers, M.F. Nuttall, P.A. Pigott, D.M. Robinson, Timothy P. Weiss, Daniel J. Wint, G.R.W. |
| author_facet | Messina, J.P. Pigott, D.M. Golding, N. Duda, K.A. Brownstein, J.S. Weiss, Daniel J. Gibson, H. Robinson, Timothy P. Gilbert, M. Wint, G.R.W. Nuttall, P.A. Gething, P.W. Myers, M.F. George, D.B. Hay, S.I. |
| author_sort | Messina, J.P. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Background Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne infection caused by a virus (CCHFV) from the Bunyaviridae family. Domestic and wild vertebrates are asymptomatic reservoirs for the virus, putting animal handlers, slaughter-house workers and agricultural labourers at highest risk in endemic areas, with secondary transmission possible through contact with infected blood and other bodily fluids. Human infection is characterized by severe symptoms that often result in death. While it is known that CCHFV transmission is limited to Africa, Asia and Europe, definitive global extents and risk patterns within these limits have not been well described. Methods We used an exhaustive database of human CCHF occurrence records and a niche modeling framework to map the global distribution of risk for human CCHF occurrence. Results A greater proportion of shrub or grass land cover was the most important contributor to our model, which predicts highest levels of risk around the Black Sea, Turkey, and some parts of central Asia. Sub-Saharan Africa shows more focalized areas of risk throughout the Sahel and the Cape region. Conclusions These new risk maps provide a valuable starting point for understanding the zoonotic niche of CCHF, its extent and the risk it poses to humans. |
| format | Journal Article |
| id | CGSpace74301 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Oxford University Press |
| publisherStr | Oxford University Press |
| record_format | dspace |
| spelling | CGSpace743012023-12-08T19:36:04Z The global distribution of Crimean-Congo hemorrhagic fever Messina, J.P. Pigott, D.M. Golding, N. Duda, K.A. Brownstein, J.S. Weiss, Daniel J. Gibson, H. Robinson, Timothy P. Gilbert, M. Wint, G.R.W. Nuttall, P.A. Gething, P.W. Myers, M.F. George, D.B. Hay, S.I. infectious diseases tickborne diseases vectorborne diseases animal diseases research health Background Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne infection caused by a virus (CCHFV) from the Bunyaviridae family. Domestic and wild vertebrates are asymptomatic reservoirs for the virus, putting animal handlers, slaughter-house workers and agricultural labourers at highest risk in endemic areas, with secondary transmission possible through contact with infected blood and other bodily fluids. Human infection is characterized by severe symptoms that often result in death. While it is known that CCHFV transmission is limited to Africa, Asia and Europe, definitive global extents and risk patterns within these limits have not been well described. Methods We used an exhaustive database of human CCHF occurrence records and a niche modeling framework to map the global distribution of risk for human CCHF occurrence. Results A greater proportion of shrub or grass land cover was the most important contributor to our model, which predicts highest levels of risk around the Black Sea, Turkey, and some parts of central Asia. Sub-Saharan Africa shows more focalized areas of risk throughout the Sahel and the Cape region. Conclusions These new risk maps provide a valuable starting point for understanding the zoonotic niche of CCHF, its extent and the risk it poses to humans. 2015-08 2016-05-24T12:25:55Z 2016-05-24T12:25:55Z Journal Article https://hdl.handle.net/10568/74301 en Open Access Oxford University Press Messinaa, J.P., Pigott, D.M., Golding, N., Duda, K.A., Brownstein, J.S., Weiss, D.J., Gibson, H., Robinson, T.P., Gilbert, M., Wint, G.R.W., Nuttall, P.A., Gething, P.W., Myers, M.F., George, D.B. and Hay, S.I. 2015. The global distribution of Crimean-Congo hemorrhagic fever. Transactions of the Royal Society of Tropical Medicine and Hygiene 109(8): 503-513. |
| spellingShingle | infectious diseases tickborne diseases vectorborne diseases animal diseases research health Messina, J.P. Pigott, D.M. Golding, N. Duda, K.A. Brownstein, J.S. Weiss, Daniel J. Gibson, H. Robinson, Timothy P. Gilbert, M. Wint, G.R.W. Nuttall, P.A. Gething, P.W. Myers, M.F. George, D.B. Hay, S.I. The global distribution of Crimean-Congo hemorrhagic fever |
| title | The global distribution of Crimean-Congo hemorrhagic fever |
| title_full | The global distribution of Crimean-Congo hemorrhagic fever |
| title_fullStr | The global distribution of Crimean-Congo hemorrhagic fever |
| title_full_unstemmed | The global distribution of Crimean-Congo hemorrhagic fever |
| title_short | The global distribution of Crimean-Congo hemorrhagic fever |
| title_sort | global distribution of crimean congo hemorrhagic fever |
| topic | infectious diseases tickborne diseases vectorborne diseases animal diseases research health |
| url | https://hdl.handle.net/10568/74301 |
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