Evaluation of oraquick® HIV-1/2 as oral rapid test
As Cameroon scales up its national HIV/AIDS control program, evaluating the performance of commercially available tests for accurate and cost effective diagnostics becomes essential. A cross-sectional study assessed the performance of an HIV oral rapid test. A total of 1520 participants consented to...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
African Journals Online
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/68343 |
| _version_ | 1855533257559375872 |
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| author | Nkenfou, C.N. Kembou, J.E. Temgoua, E.S. Djikeng, Appolinaire Mouafo, L.M. Ndzie, E.N. Donkam, I. Colizzi, V. SanouSobze, M. |
| author_browse | Colizzi, V. Djikeng, Appolinaire Donkam, I. Kembou, J.E. Mouafo, L.M. Ndzie, E.N. Nkenfou, C.N. SanouSobze, M. Temgoua, E.S. |
| author_facet | Nkenfou, C.N. Kembou, J.E. Temgoua, E.S. Djikeng, Appolinaire Mouafo, L.M. Ndzie, E.N. Donkam, I. Colizzi, V. SanouSobze, M. |
| author_sort | Nkenfou, C.N. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | As Cameroon scales up its national HIV/AIDS control program, evaluating the performance of commercially available tests for accurate and cost effective diagnostics becomes essential. A cross-sectional study assessed the performance
of an HIV oral rapid test. A total of 1520 participants consented to participate in the study. After counselling, they were tested for HIV using the national algorithm followed by OraQuick. Results of the national algorithm were compared to those
of OraQuick, for sensitivity, specificity, positive predictive and negative predictive values. 62% of participants were male, and 1% was reported HIV-positive following the national algorithm. The OraQuick test had 93% sensitivity, 99% specificity, 99.93% NPV and 90% PPV (95% CI, Kappa 0.965). Though more expensive (2-6x) compared to the national algorithm tests, oral mucosal transudate-based test demonstrated good performance. Therefore, it could be implemented in resource constrained settings if subsidized and could increase participation since less invasive with no blood accident exposure. |
| format | Journal Article |
| id | CGSpace68343 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2013 |
| publishDateRange | 2013 |
| publishDateSort | 2013 |
| publisher | African Journals Online |
| publisherStr | African Journals Online |
| record_format | dspace |
| spelling | CGSpace683432024-05-01T08:18:38Z Evaluation of oraquick® HIV-1/2 as oral rapid test Nkenfou, C.N. Kembou, J.E. Temgoua, E.S. Djikeng, Appolinaire Mouafo, L.M. Ndzie, E.N. Donkam, I. Colizzi, V. SanouSobze, M. human diseases health As Cameroon scales up its national HIV/AIDS control program, evaluating the performance of commercially available tests for accurate and cost effective diagnostics becomes essential. A cross-sectional study assessed the performance of an HIV oral rapid test. A total of 1520 participants consented to participate in the study. After counselling, they were tested for HIV using the national algorithm followed by OraQuick. Results of the national algorithm were compared to those of OraQuick, for sensitivity, specificity, positive predictive and negative predictive values. 62% of participants were male, and 1% was reported HIV-positive following the national algorithm. The OraQuick test had 93% sensitivity, 99% specificity, 99.93% NPV and 90% PPV (95% CI, Kappa 0.965). Though more expensive (2-6x) compared to the national algorithm tests, oral mucosal transudate-based test demonstrated good performance. Therefore, it could be implemented in resource constrained settings if subsidized and could increase participation since less invasive with no blood accident exposure. 2013 2015-09-30T10:55:51Z 2015-09-30T10:55:51Z Journal Article https://hdl.handle.net/10568/68343 en Open Access African Journals Online Nkenfou, C.N., Kembou, J.E., Temgoua, E.S., Djikeng, A., Mouafo, L.M., Ndzie, E.N., Donkam, I., Colizzi, V. and SanouSobzé, M. 2013. Evaluation of Oraquick® HIV-1/2 as oral rapid test. African Journal of Infectious Diseases 7: 27-30. |
| spellingShingle | human diseases health Nkenfou, C.N. Kembou, J.E. Temgoua, E.S. Djikeng, Appolinaire Mouafo, L.M. Ndzie, E.N. Donkam, I. Colizzi, V. SanouSobze, M. Evaluation of oraquick® HIV-1/2 as oral rapid test |
| title | Evaluation of oraquick® HIV-1/2 as oral rapid test |
| title_full | Evaluation of oraquick® HIV-1/2 as oral rapid test |
| title_fullStr | Evaluation of oraquick® HIV-1/2 as oral rapid test |
| title_full_unstemmed | Evaluation of oraquick® HIV-1/2 as oral rapid test |
| title_short | Evaluation of oraquick® HIV-1/2 as oral rapid test |
| title_sort | evaluation of oraquick r hiv 1 2 as oral rapid test |
| topic | human diseases health |
| url | https://hdl.handle.net/10568/68343 |
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