The burden of human African trypanosomiasis

Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis. We review current knowledge on the burden of HAT in su...

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Detalles Bibliográficos
Autores principales: Fèvre, Eric M., Wissmann, B.V., Welburn, S.C., Lutumba, P.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://hdl.handle.net/10568/61880
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author Fèvre, Eric M.
Wissmann, B.V.
Welburn, S.C.
Lutumba, P.
author_browse Fèvre, Eric M.
Lutumba, P.
Welburn, S.C.
Wissmann, B.V.
author_facet Fèvre, Eric M.
Wissmann, B.V.
Welburn, S.C.
Lutumba, P.
author_sort Fèvre, Eric M.
collection Repository of Agricultural Research Outputs (CGSpace)
description Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis. We review current knowledge on the burden of HAT in sub-Saharan Africa, with an emphasis on the disability-adjusted life year (DALY), data sources, and methodological issues relating to the use of this metric for assessing the burden of this disease. We highlight areas where data are lacking to properly quantify the impact of these diseases, mainly relating to quantifying under-reporting and disability associated with infection, and challenge the HAT research community to tackle the neglect in data gathering to enable better evidence-based assessments of burden using DALYs or other appropriate measures.
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spelling CGSpace618802024-06-26T09:37:29Z The burden of human African trypanosomiasis Fèvre, Eric M. Wissmann, B.V. Welburn, S.C. Lutumba, P. trypanosomiasis disease control animal diseases zoonoses Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis. We review current knowledge on the burden of HAT in sub-Saharan Africa, with an emphasis on the disability-adjusted life year (DALY), data sources, and methodological issues relating to the use of this metric for assessing the burden of this disease. We highlight areas where data are lacking to properly quantify the impact of these diseases, mainly relating to quantifying under-reporting and disability associated with infection, and challenge the HAT research community to tackle the neglect in data gathering to enable better evidence-based assessments of burden using DALYs or other appropriate measures. 2008-12-23 2015-03-25T09:09:40Z 2015-03-25T09:09:40Z Journal Article https://hdl.handle.net/10568/61880 en Open Access Public Library of Science PLoS Neglected Tropical Diseases 2008;2(12):e333.
spellingShingle trypanosomiasis
disease control
animal diseases
zoonoses
Fèvre, Eric M.
Wissmann, B.V.
Welburn, S.C.
Lutumba, P.
The burden of human African trypanosomiasis
title The burden of human African trypanosomiasis
title_full The burden of human African trypanosomiasis
title_fullStr The burden of human African trypanosomiasis
title_full_unstemmed The burden of human African trypanosomiasis
title_short The burden of human African trypanosomiasis
title_sort burden of human african trypanosomiasis
topic trypanosomiasis
disease control
animal diseases
zoonoses
url https://hdl.handle.net/10568/61880
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