The effects of resistance to trypanocidal drugs on trypanosome transmission

Tsetse-transmitted trypanosomosis affects cattle production over approximately 10 million km2 of Africa. In these areas, trypanocidal drugs, both prophylactic and curative, are the most widely used methods of trypanosomosis control. However, resistance of trypanosomes to the 3 trypanocidal drugs use...

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Autores principales: McDermott, John J., Coleman, P.G., Eisler, M.C., Peregrine, A.S.
Formato: Conference Paper
Lenguaje:Inglés
Publicado: International Society for Veterinary Epidemiology and Economics 2000
Materias:
Acceso en línea:https://hdl.handle.net/10568/51156
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author McDermott, John J.
Coleman, P.G.
Eisler, M.C.
Peregrine, A.S.
author_browse Coleman, P.G.
Eisler, M.C.
McDermott, John J.
Peregrine, A.S.
author_facet McDermott, John J.
Coleman, P.G.
Eisler, M.C.
Peregrine, A.S.
author_sort McDermott, John J.
collection Repository of Agricultural Research Outputs (CGSpace)
description Tsetse-transmitted trypanosomosis affects cattle production over approximately 10 million km2 of Africa. In these areas, trypanocidal drugs, both prophylactic and curative, are the most widely used methods of trypanosomosis control. However, resistance of trypanosomes to the 3 trypanocidal drugs used in cattle (salts of isometamidium, diminsine and homidium) has been widely Reported and is considered to be increasing. The worst problems of trypanocidal drag resistance appear to occur where cattle are frequently treated in response to high trypanosome challenge. New trypanocides are unlikely to be developed because of low expected commercial retains . Thus, an important consideration in all trypanosomosis control programmes is how to either preserve the efficacy of trypanocides or, where widespread resistance exists, minimize its effects. In this paper, we explore the effects of drug resistance on trypanosome transmission under 3 important field scenarios.
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spelling CGSpace511562016-05-30T17:53:21Z The effects of resistance to trypanocidal drugs on trypanosome transmission McDermott, John J. Coleman, P.G. Eisler, M.C. Peregrine, A.S. trypanosomes (phytomonas) drug resistance disease transmission models cattle wildlife Tsetse-transmitted trypanosomosis affects cattle production over approximately 10 million km2 of Africa. In these areas, trypanocidal drugs, both prophylactic and curative, are the most widely used methods of trypanosomosis control. However, resistance of trypanosomes to the 3 trypanocidal drugs used in cattle (salts of isometamidium, diminsine and homidium) has been widely Reported and is considered to be increasing. The worst problems of trypanocidal drag resistance appear to occur where cattle are frequently treated in response to high trypanosome challenge. New trypanocides are unlikely to be developed because of low expected commercial retains . Thus, an important consideration in all trypanosomosis control programmes is how to either preserve the efficacy of trypanocides or, where widespread resistance exists, minimize its effects. In this paper, we explore the effects of drug resistance on trypanosome transmission under 3 important field scenarios. 2000 2014-10-31T06:22:10Z 2014-10-31T06:22:10Z Conference Paper https://hdl.handle.net/10568/51156 en Limited Access International Society for Veterinary Epidemiology and Economics
spellingShingle trypanosomes (phytomonas)
drug resistance
disease transmission
models
cattle
wildlife
McDermott, John J.
Coleman, P.G.
Eisler, M.C.
Peregrine, A.S.
The effects of resistance to trypanocidal drugs on trypanosome transmission
title The effects of resistance to trypanocidal drugs on trypanosome transmission
title_full The effects of resistance to trypanocidal drugs on trypanosome transmission
title_fullStr The effects of resistance to trypanocidal drugs on trypanosome transmission
title_full_unstemmed The effects of resistance to trypanocidal drugs on trypanosome transmission
title_short The effects of resistance to trypanocidal drugs on trypanosome transmission
title_sort effects of resistance to trypanocidal drugs on trypanosome transmission
topic trypanosomes (phytomonas)
drug resistance
disease transmission
models
cattle
wildlife
url https://hdl.handle.net/10568/51156
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