Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda
Background <i>Taenia solium</i> is a zoonotic helminth with the potential to cause life threatening epilepsy in people through the aberrant larval infection of the brain called Neurocysticercosis (NCC). The pig is the intermediate host for <i>T. solium</i> where the larval form, cysticercus cellul...
| Autores principales: | , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Springer
2014
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/45948 |
| _version_ | 1855527032029446144 |
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| author | Nsadha, Z. Thomas, Lian F. Fèvre, Eric M. Nasinyama, G. Ojok, L. Waiswa, C. |
| author_browse | Fèvre, Eric M. Nasinyama, G. Nsadha, Z. Ojok, L. Thomas, Lian F. Waiswa, C. |
| author_facet | Nsadha, Z. Thomas, Lian F. Fèvre, Eric M. Nasinyama, G. Ojok, L. Waiswa, C. |
| author_sort | Nsadha, Z. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Background
<i>Taenia solium</i> is a zoonotic helminth with the potential to cause life threatening epilepsy in people through the aberrant larval infection of the brain called Neurocysticercosis (NCC). The pig is the intermediate host for <i>T. solium</i> where the larval form, cysticercus cellulosae, normally develops after the pig eats eggs of the parasite. Humans are the definitive host where the adult tapeworm develops and are infected through the consumption of poorly cooked, infected meat. <i>T. solium</i> has been acknowledged by the World Health Organization (WHO), Food and Agriculture Organization (FAO) and UK Department for International Development (DFID) as being a neglected zoonotic disease, and was recently was included in the WHO roadmap for control of neglected tropical diseases. This neglect encompasses a lack of epidemiological data and a lack of validated, effective control strategies being adopted. Understanding the epidemiology of this parasite in the intermediate host is the first step towards designing suitable intervention strategies for the improvement of public health. This study was undertaken to provide an accurate and up-to-date estimate for the prevalence of porcine cysticercosis in the Lake Kyoga basin.
Results
Sera from 378 pigs were analysed with the HP10 Antigen Enzyme Linked Immunosorbant Assay (ELISA) and the prevalence was found to be 25.7% (95% confidence interval 21.0% to 30.0%). Previous sero- surveillance in this region, using the B158/B60 Ag Elisa had indicated a prevalence of 8.6% in 2005 indicating a dramatic increase in prevalence (J. Parasitol Res, Article ID 375493, 2009) within a 6-year period.
Conclusion
This increasing prevalence in the disease indicates to us that there is currently no effective control of this parasite and that in this region of Uganda at least; cysticercosis remains a neglected zoonotic disease. |
| format | Journal Article |
| id | CGSpace45948 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | CGSpace459482025-05-30T10:38:47Z Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda Nsadha, Z. Thomas, Lian F. Fèvre, Eric M. Nasinyama, G. Ojok, L. Waiswa, C. animal diseases swine zoonoses Background <i>Taenia solium</i> is a zoonotic helminth with the potential to cause life threatening epilepsy in people through the aberrant larval infection of the brain called Neurocysticercosis (NCC). The pig is the intermediate host for <i>T. solium</i> where the larval form, cysticercus cellulosae, normally develops after the pig eats eggs of the parasite. Humans are the definitive host where the adult tapeworm develops and are infected through the consumption of poorly cooked, infected meat. <i>T. solium</i> has been acknowledged by the World Health Organization (WHO), Food and Agriculture Organization (FAO) and UK Department for International Development (DFID) as being a neglected zoonotic disease, and was recently was included in the WHO roadmap for control of neglected tropical diseases. This neglect encompasses a lack of epidemiological data and a lack of validated, effective control strategies being adopted. Understanding the epidemiology of this parasite in the intermediate host is the first step towards designing suitable intervention strategies for the improvement of public health. This study was undertaken to provide an accurate and up-to-date estimate for the prevalence of porcine cysticercosis in the Lake Kyoga basin. Results Sera from 378 pigs were analysed with the HP10 Antigen Enzyme Linked Immunosorbant Assay (ELISA) and the prevalence was found to be 25.7% (95% confidence interval 21.0% to 30.0%). Previous sero- surveillance in this region, using the B158/B60 Ag Elisa had indicated a prevalence of 8.6% in 2005 indicating a dramatic increase in prevalence (J. Parasitol Res, Article ID 375493, 2009) within a 6-year period. Conclusion This increasing prevalence in the disease indicates to us that there is currently no effective control of this parasite and that in this region of Uganda at least; cysticercosis remains a neglected zoonotic disease. 2014-12 2014-10-13T04:34:16Z 2014-10-13T04:34:16Z Journal Article https://hdl.handle.net/10568/45948 en Open Access Springer Nsadha, Z., Thomas, L.F., Fèvre, E.M., Nasinyama, G., Ojok, L. and Waiswa, C. 2014. Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda. BMC Veterinary Research 10: 239. |
| spellingShingle | animal diseases swine zoonoses Nsadha, Z. Thomas, Lian F. Fèvre, Eric M. Nasinyama, G. Ojok, L. Waiswa, C. Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda |
| title | Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda |
| title_full | Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda |
| title_fullStr | Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda |
| title_full_unstemmed | Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda |
| title_short | Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda |
| title_sort | prevalence of porcine cysticercosis in the lake kyoga basin uganda |
| topic | animal diseases swine zoonoses |
| url | https://hdl.handle.net/10568/45948 |
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