Selection mapping of loci for quantitative disease resistance in a diverse maize population

The selection response of a complex maize population improved primarily for quantitative disease resistance to northern leaf blight (NLB) and secondarily for common rust resistance and agronomic phenotypes was investigated at the molecular genetic level. A tiered marker analysis with 151 simple sequ...

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Autores principales: Wisser, RJ, Murray, SC, Kolkman, Judith M., Ceballos, H., Nelson, R.J.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://hdl.handle.net/10568/44082
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author Wisser, RJ
Murray, SC
Kolkman, Judith M.
Ceballos, H.
Nelson, R.J.
author_browse Ceballos, H.
Kolkman, Judith M.
Murray, SC
Nelson, R.J.
Wisser, RJ
author_facet Wisser, RJ
Murray, SC
Kolkman, Judith M.
Ceballos, H.
Nelson, R.J.
author_sort Wisser, RJ
collection Repository of Agricultural Research Outputs (CGSpace)
description The selection response of a complex maize population improved primarily for quantitative disease resistance to northern leaf blight (NLB) and secondarily for common rust resistance and agronomic phenotypes was investigated at the molecular genetic level. A tiered marker analysis with 151 simple sequence repeat (SSR) markers in 90 individuals of the population indicated that on average six alleles per locus were available for selection. An improved test statistic for selection mapping was developed, in which quantitative trait loci (QTL) are identified through the analysis of allele-frequency shifts at mapped multiallelic loci over generations of selection. After correcting for the multiple tests performed, 25 SSR loci showed evidence of selection. Many of the putatively selected loci were unlinked and dispersed across the genome, which was consistent with the diffuse distribution of previously published QTL for NLB resistance. Compelling evidence for selection was found on maize chromosome 8, where several putatively selected loci colocalized with published NLB QTL and a race-specific resistance gene. Analysis of F2 populations derived from the selection mapping population suggested that multiple linked loci in this chromosomal segment were, in part, responsible for the selection response for quantitative resistance to NLB.
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spelling CGSpace440822024-08-27T10:36:44Z Selection mapping of loci for quantitative disease resistance in a diverse maize population Wisser, RJ Murray, SC Kolkman, Judith M. Ceballos, H. Nelson, R.J. zea mays maize selection genotypes quantitative trait loci disease resistance maíz selección genotipos loci de rasgos cuantitativos resistencia a la enfermedad The selection response of a complex maize population improved primarily for quantitative disease resistance to northern leaf blight (NLB) and secondarily for common rust resistance and agronomic phenotypes was investigated at the molecular genetic level. A tiered marker analysis with 151 simple sequence repeat (SSR) markers in 90 individuals of the population indicated that on average six alleles per locus were available for selection. An improved test statistic for selection mapping was developed, in which quantitative trait loci (QTL) are identified through the analysis of allele-frequency shifts at mapped multiallelic loci over generations of selection. After correcting for the multiple tests performed, 25 SSR loci showed evidence of selection. Many of the putatively selected loci were unlinked and dispersed across the genome, which was consistent with the diffuse distribution of previously published QTL for NLB resistance. Compelling evidence for selection was found on maize chromosome 8, where several putatively selected loci colocalized with published NLB QTL and a race-specific resistance gene. Analysis of F2 populations derived from the selection mapping population suggested that multiple linked loci in this chromosomal segment were, in part, responsible for the selection response for quantitative resistance to NLB. 2008-09-01 2014-10-02T08:33:12Z 2014-10-02T08:33:12Z Journal Article https://hdl.handle.net/10568/44082 en Open Access Oxford University Press
spellingShingle zea mays
maize
selection
genotypes
quantitative trait loci
disease resistance
maíz
selección
genotipos
loci de rasgos cuantitativos
resistencia a la enfermedad
Wisser, RJ
Murray, SC
Kolkman, Judith M.
Ceballos, H.
Nelson, R.J.
Selection mapping of loci for quantitative disease resistance in a diverse maize population
title Selection mapping of loci for quantitative disease resistance in a diverse maize population
title_full Selection mapping of loci for quantitative disease resistance in a diverse maize population
title_fullStr Selection mapping of loci for quantitative disease resistance in a diverse maize population
title_full_unstemmed Selection mapping of loci for quantitative disease resistance in a diverse maize population
title_short Selection mapping of loci for quantitative disease resistance in a diverse maize population
title_sort selection mapping of loci for quantitative disease resistance in a diverse maize population
topic zea mays
maize
selection
genotypes
quantitative trait loci
disease resistance
maíz
selección
genotipos
loci de rasgos cuantitativos
resistencia a la enfermedad
url https://hdl.handle.net/10568/44082
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