Infection-interactions in Ethiopian village chickens

Chickens raised under village production systems are exposed to a wide variety of pathogens, and current or previous infections may affect their susceptibility to further infections with another parasite, and/or can alter the manifestation of each infection. It is possible that co-infections may be...

Full description

Bibliographic Details
Main Authors: Bettridge, Judy M., Lynch, Stacey E., Brena, M.C., Melese, K., Dessie, Tadelle, Terfa, Z.G., Desta, T.T., Rushton, S., Hanotte, Olivier H., Kaiser, P., Wigley, Paul, Christley, Robert M.
Format: Journal Article
Language:Inglés
Published: Elsevier 2014
Subjects:
Online Access:https://hdl.handle.net/10568/43784
_version_ 1855541072726327296
author Bettridge, Judy M.
Lynch, Stacey E.
Brena, M.C.
Melese, K.
Dessie, Tadelle
Terfa, Z.G.
Desta, T.T.
Rushton, S.
Hanotte, Olivier H.
Kaiser, P.
Wigley, Paul
Christley, Robert M.
author_browse Bettridge, Judy M.
Brena, M.C.
Christley, Robert M.
Dessie, Tadelle
Desta, T.T.
Hanotte, Olivier H.
Kaiser, P.
Lynch, Stacey E.
Melese, K.
Rushton, S.
Terfa, Z.G.
Wigley, Paul
author_facet Bettridge, Judy M.
Lynch, Stacey E.
Brena, M.C.
Melese, K.
Dessie, Tadelle
Terfa, Z.G.
Desta, T.T.
Rushton, S.
Hanotte, Olivier H.
Kaiser, P.
Wigley, Paul
Christley, Robert M.
author_sort Bettridge, Judy M.
collection Repository of Agricultural Research Outputs (CGSpace)
description Chickens raised under village production systems are exposed to a wide variety of pathogens, and current or previous infections may affect their susceptibility to further infections with another parasite, and/or can alter the manifestation of each infection. It is possible that co-infections may be as important as environmental risk factors. However, in cross-sectional studies, where the timing of infection is unknown, apparent associations between infections may be observed due to parasites sharing common risk factors. This study measured antibody titres to 3 viral (Newcastle disease, Marek's disease and infectious bursal disease) and 2 bacterial (Pasteurella multocida and Salmonella) diseases, and the infection prevalence of 3 families of endo- and ecto-parasites (Ascaridida, Eimeria and lice) in 1056 village chickens from two geographically distinct populations in Ethiopia. Samples were collected during 4 cross-sectional surveys, each approximately 6 months apart. Constrained ordination, a technique for analysis of ecological community data, was used to explore this complex dataset and enabled potential relationships to be uncovered and tested despite the different measurements used for the different parasites. It was found that only a small proportion of variation in the data could be explained by the risk factors measured. Very few birds (9/1280) were found to be seropositive to Newcastle disease. Positive relationships were identified between Pasteurella and Salmonella titres; and between Marek's disease and parasitic infections, and these two groups of diseases were correlated with females and males, respectively. This may suggest differences in the way that the immune systems of male and female chickens interact with these parasites. In conclusion, we find that a number of infectious pathogens and their interactions are likely to impact village chicken health and production. Control of these infections is likely to be of importance in future development planning.
format Journal Article
id CGSpace43784
institution CGIAR Consortium
language Inglés
publishDate 2014
publishDateRange 2014
publishDateSort 2014
publisher Elsevier
publisherStr Elsevier
record_format dspace
spelling CGSpace437842024-01-09T09:50:25Z Infection-interactions in Ethiopian village chickens Bettridge, Judy M. Lynch, Stacey E. Brena, M.C. Melese, K. Dessie, Tadelle Terfa, Z.G. Desta, T.T. Rushton, S. Hanotte, Olivier H. Kaiser, P. Wigley, Paul Christley, Robert M. poultry animal diseases animal health Chickens raised under village production systems are exposed to a wide variety of pathogens, and current or previous infections may affect their susceptibility to further infections with another parasite, and/or can alter the manifestation of each infection. It is possible that co-infections may be as important as environmental risk factors. However, in cross-sectional studies, where the timing of infection is unknown, apparent associations between infections may be observed due to parasites sharing common risk factors. This study measured antibody titres to 3 viral (Newcastle disease, Marek's disease and infectious bursal disease) and 2 bacterial (Pasteurella multocida and Salmonella) diseases, and the infection prevalence of 3 families of endo- and ecto-parasites (Ascaridida, Eimeria and lice) in 1056 village chickens from two geographically distinct populations in Ethiopia. Samples were collected during 4 cross-sectional surveys, each approximately 6 months apart. Constrained ordination, a technique for analysis of ecological community data, was used to explore this complex dataset and enabled potential relationships to be uncovered and tested despite the different measurements used for the different parasites. It was found that only a small proportion of variation in the data could be explained by the risk factors measured. Very few birds (9/1280) were found to be seropositive to Newcastle disease. Positive relationships were identified between Pasteurella and Salmonella titres; and between Marek's disease and parasitic infections, and these two groups of diseases were correlated with females and males, respectively. This may suggest differences in the way that the immune systems of male and female chickens interact with these parasites. In conclusion, we find that a number of infectious pathogens and their interactions are likely to impact village chicken health and production. Control of these infections is likely to be of importance in future development planning. 2014-11 2014-09-29T14:54:22Z 2014-09-29T14:54:22Z Journal Article https://hdl.handle.net/10568/43784 en Open Access Elsevier Bettridge, J.M., Lynch, S.E., Brena, M.C., Melese, K., Dessie, T., Terfa, Z.G., Desta, T., Rushton, S., Hanotte, O., Kaiser, P., Wigley, P. and Christley, R.M. 2014. Infection-interactions in Ethiopian village chickens. Preventive Veterinary Medicine 117(2): 358-366.
spellingShingle poultry
animal diseases
animal health
Bettridge, Judy M.
Lynch, Stacey E.
Brena, M.C.
Melese, K.
Dessie, Tadelle
Terfa, Z.G.
Desta, T.T.
Rushton, S.
Hanotte, Olivier H.
Kaiser, P.
Wigley, Paul
Christley, Robert M.
Infection-interactions in Ethiopian village chickens
title Infection-interactions in Ethiopian village chickens
title_full Infection-interactions in Ethiopian village chickens
title_fullStr Infection-interactions in Ethiopian village chickens
title_full_unstemmed Infection-interactions in Ethiopian village chickens
title_short Infection-interactions in Ethiopian village chickens
title_sort infection interactions in ethiopian village chickens
topic poultry
animal diseases
animal health
url https://hdl.handle.net/10568/43784
work_keys_str_mv AT bettridgejudym infectioninteractionsinethiopianvillagechickens
AT lynchstaceye infectioninteractionsinethiopianvillagechickens
AT brenamc infectioninteractionsinethiopianvillagechickens
AT melesek infectioninteractionsinethiopianvillagechickens
AT dessietadelle infectioninteractionsinethiopianvillagechickens
AT terfazg infectioninteractionsinethiopianvillagechickens
AT destatt infectioninteractionsinethiopianvillagechickens
AT rushtons infectioninteractionsinethiopianvillagechickens
AT hanotteolivierh infectioninteractionsinethiopianvillagechickens
AT kaiserp infectioninteractionsinethiopianvillagechickens
AT wigleypaul infectioninteractionsinethiopianvillagechickens
AT christleyrobertm infectioninteractionsinethiopianvillagechickens