Identifying resistance gene analogs associated with resistances to different pathogens in common beans

A polymerase chain reaction approach using degenerate primers that targeted the conserved domains of cloned plant disease resistance genes (R genes) was used to isolate a set of 15 resistance gene analogs (RGAs) from common bean (Phaseolus vulgaris). Eight different classes of RGAs were obtained fro...

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Main Authors: López, C.E., Acosta, I.F., Jara, Carlos E., Pedraza García, Fabio, Gaitán Solís, Eliana, Gallego Sánchez, Gerardo J., Beebe, Stephen E., Tohme, Joseph M.
Format: Journal Article
Language:Inglés
Published: Scientific Societies 2003
Subjects:
Online Access:https://hdl.handle.net/10568/42953
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author López, C.E.
Acosta, I.F.
Jara, Carlos E.
Pedraza García, Fabio
Gaitán Solís, Eliana
Gallego Sánchez, Gerardo J.
Beebe, Stephen E.
Tohme, Joseph M.
author_browse Acosta, I.F.
Beebe, Stephen E.
Gaitán Solís, Eliana
Gallego Sánchez, Gerardo J.
Jara, Carlos E.
López, C.E.
Pedraza García, Fabio
Tohme, Joseph M.
author_facet López, C.E.
Acosta, I.F.
Jara, Carlos E.
Pedraza García, Fabio
Gaitán Solís, Eliana
Gallego Sánchez, Gerardo J.
Beebe, Stephen E.
Tohme, Joseph M.
author_sort López, C.E.
collection Repository of Agricultural Research Outputs (CGSpace)
description A polymerase chain reaction approach using degenerate primers that targeted the conserved domains of cloned plant disease resistance genes (R genes) was used to isolate a set of 15 resistance gene analogs (RGAs) from common bean (Phaseolus vulgaris). Eight different classes of RGAs were obtained from nucleotide binding site (NBS)-based primers and seven from not previously described Toll/Interleukin-1 receptor-like (TIR)-based primers. Putative amino acid sequences of RGAs were significantly similar to R genes and contained additional conserved motifs. The NBS-type RGAs were classified in two subgroups according to the expected final residue in the kinase-2 motif. Eleven RGAs were mapped at 19 loci on eight linkage groups of the common bean genetic map constructed at Centro Internacional de Agricultura Tropical. Genetic linkage was shown for eight RGAs with partial resistance to anthracnose, angular leaf spot (ALS) and Bean golden yellow mosaic virus (BGYMV). RGA1 and RGA2 were associated with resistance loci to anthracnose and BGYMV and were part of two clusters of R genes previously described. A new major cluster was detected by RGA7 and explained up to 63.9% of resistance to ALS and has a putative contribution to anthracnose resistance. These results show the usefulness of RGAs as candidate genes to detect and eventually isolate numerous R genes in common bean.
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spelling CGSpace429532024-04-25T06:01:44Z Identifying resistance gene analogs associated with resistances to different pathogens in common beans López, C.E. Acosta, I.F. Jara, Carlos E. Pedraza García, Fabio Gaitán Solís, Eliana Gallego Sánchez, Gerardo J. Beebe, Stephen E. Tohme, Joseph M. phaseolus vulgaris genes disease resistance genetic resistance genetic markers resistencia a la enfermedad resistencia genética marcadores genéticos A polymerase chain reaction approach using degenerate primers that targeted the conserved domains of cloned plant disease resistance genes (R genes) was used to isolate a set of 15 resistance gene analogs (RGAs) from common bean (Phaseolus vulgaris). Eight different classes of RGAs were obtained from nucleotide binding site (NBS)-based primers and seven from not previously described Toll/Interleukin-1 receptor-like (TIR)-based primers. Putative amino acid sequences of RGAs were significantly similar to R genes and contained additional conserved motifs. The NBS-type RGAs were classified in two subgroups according to the expected final residue in the kinase-2 motif. Eleven RGAs were mapped at 19 loci on eight linkage groups of the common bean genetic map constructed at Centro Internacional de Agricultura Tropical. Genetic linkage was shown for eight RGAs with partial resistance to anthracnose, angular leaf spot (ALS) and Bean golden yellow mosaic virus (BGYMV). RGA1 and RGA2 were associated with resistance loci to anthracnose and BGYMV and were part of two clusters of R genes previously described. A new major cluster was detected by RGA7 and explained up to 63.9% of resistance to ALS and has a putative contribution to anthracnose resistance. These results show the usefulness of RGAs as candidate genes to detect and eventually isolate numerous R genes in common bean. 2003-01 2014-09-24T07:58:49Z 2014-09-24T07:58:49Z Journal Article https://hdl.handle.net/10568/42953 en Open Access Scientific Societies López, Camilo Ernesto; Acosta, Iván F.; Jara, Carlos E.; Pedraza García, Fabio; Gaitán Solís, Eliana; Gallego, Gerardo J.; Beebe, Stephen E.; Tohme M., Joseph. 2003. Identifying resistance gene analogs associated with resistances to different pathogens in common beans . Phytopathology (USA) 93(1):88-95.
spellingShingle phaseolus vulgaris
genes
disease resistance
genetic resistance
genetic markers
resistencia a la enfermedad
resistencia genética
marcadores genéticos
López, C.E.
Acosta, I.F.
Jara, Carlos E.
Pedraza García, Fabio
Gaitán Solís, Eliana
Gallego Sánchez, Gerardo J.
Beebe, Stephen E.
Tohme, Joseph M.
Identifying resistance gene analogs associated with resistances to different pathogens in common beans
title Identifying resistance gene analogs associated with resistances to different pathogens in common beans
title_full Identifying resistance gene analogs associated with resistances to different pathogens in common beans
title_fullStr Identifying resistance gene analogs associated with resistances to different pathogens in common beans
title_full_unstemmed Identifying resistance gene analogs associated with resistances to different pathogens in common beans
title_short Identifying resistance gene analogs associated with resistances to different pathogens in common beans
title_sort identifying resistance gene analogs associated with resistances to different pathogens in common beans
topic phaseolus vulgaris
genes
disease resistance
genetic resistance
genetic markers
resistencia a la enfermedad
resistencia genética
marcadores genéticos
url https://hdl.handle.net/10568/42953
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