Genetic mapping of a dominant gene conferring resistance to cassava mosaic disease

Cassava mosaic disease (CMD) is the most-important disease of cassava (Manihot esculenta) in Africa, and is a potential threat to Latin American (LA) cassava production. Although this viral disease is still unknown in LA, its vector – the whitefly – has recently been found. The disease is best contr...

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Autores principales: Akano, A.O., Dixon, Alfred G.O., Mba, C, Barrera Sabogal, E., Fregene, Martin A.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Springer 2002
Materias:
Acceso en línea:https://hdl.handle.net/10568/42896
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author Akano, A.O.
Dixon, Alfred G.O.
Mba, C
Barrera Sabogal, E.
Fregene, Martin A.
author_browse Akano, A.O.
Barrera Sabogal, E.
Dixon, Alfred G.O.
Fregene, Martin A.
Mba, C
author_facet Akano, A.O.
Dixon, Alfred G.O.
Mba, C
Barrera Sabogal, E.
Fregene, Martin A.
author_sort Akano, A.O.
collection Repository of Agricultural Research Outputs (CGSpace)
description Cassava mosaic disease (CMD) is the most-important disease of cassava (Manihot esculenta) in Africa, and is a potential threat to Latin American (LA) cassava production. Although this viral disease is still unknown in LA, its vector – the whitefly – has recently been found. The disease is best controlled through host-plant resistance, which was first found in third backcross derivatives of an interspecific cross between cassava and Manihot glaziovii, and is thought to be polygenic. Recently, high levels of resistance were also found in several Nigerian cassava landraces. Classical genetic analysis and molecular genetic-mapping of the landraces showed that a major dominant gene confers this resistance. Bulk segregant analysis (BSA) was used to quickly identify a simple sequence repeat (SSR) marker linked to the CMD-resistance gene. The marker, SSRY28, is located on linkage group R of the male-parent-derived molecular genetic map. The gene, designated as CMD2, is flanked by the SSR and RFLP marker GY1 at 9 and 8 cM, respectively. To our knowledge, this is the first report of qualitative virus resistance in cassava, and of molecular markers that tag CMD resistance in cassava. We discuss the use of markers linked to CMD2 for marker-assisted breeding of CMD resistance in Latin America and for increasing the cost-effectiveness of resistance breeding in Africa.
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spelling CGSpace428962024-08-27T10:35:40Z Genetic mapping of a dominant gene conferring resistance to cassava mosaic disease Akano, A.O. Dixon, Alfred G.O. Mba, C Barrera Sabogal, E. Fregene, Martin A. manihot esculenta african cassava mosaic virus genetic markers genetic maps disease resistance genetic resistance genotypes pcr virus del mosaico de la cassava marcadores genéticos mapas genéticos resistencia a la enfermedad resistencia genética genotipos Cassava mosaic disease (CMD) is the most-important disease of cassava (Manihot esculenta) in Africa, and is a potential threat to Latin American (LA) cassava production. Although this viral disease is still unknown in LA, its vector – the whitefly – has recently been found. The disease is best controlled through host-plant resistance, which was first found in third backcross derivatives of an interspecific cross between cassava and Manihot glaziovii, and is thought to be polygenic. Recently, high levels of resistance were also found in several Nigerian cassava landraces. Classical genetic analysis and molecular genetic-mapping of the landraces showed that a major dominant gene confers this resistance. Bulk segregant analysis (BSA) was used to quickly identify a simple sequence repeat (SSR) marker linked to the CMD-resistance gene. The marker, SSRY28, is located on linkage group R of the male-parent-derived molecular genetic map. The gene, designated as CMD2, is flanked by the SSR and RFLP marker GY1 at 9 and 8 cM, respectively. To our knowledge, this is the first report of qualitative virus resistance in cassava, and of molecular markers that tag CMD resistance in cassava. We discuss the use of markers linked to CMD2 for marker-assisted breeding of CMD resistance in Latin America and for increasing the cost-effectiveness of resistance breeding in Africa. 2002-09 2014-09-24T07:58:44Z 2014-09-24T07:58:44Z Journal Article https://hdl.handle.net/10568/42896 en Limited Access Springer
spellingShingle manihot esculenta
african cassava mosaic virus
genetic markers
genetic maps
disease resistance
genetic resistance
genotypes
pcr
virus del mosaico de la cassava
marcadores genéticos
mapas genéticos
resistencia a la enfermedad
resistencia genética
genotipos
Akano, A.O.
Dixon, Alfred G.O.
Mba, C
Barrera Sabogal, E.
Fregene, Martin A.
Genetic mapping of a dominant gene conferring resistance to cassava mosaic disease
title Genetic mapping of a dominant gene conferring resistance to cassava mosaic disease
title_full Genetic mapping of a dominant gene conferring resistance to cassava mosaic disease
title_fullStr Genetic mapping of a dominant gene conferring resistance to cassava mosaic disease
title_full_unstemmed Genetic mapping of a dominant gene conferring resistance to cassava mosaic disease
title_short Genetic mapping of a dominant gene conferring resistance to cassava mosaic disease
title_sort genetic mapping of a dominant gene conferring resistance to cassava mosaic disease
topic manihot esculenta
african cassava mosaic virus
genetic markers
genetic maps
disease resistance
genetic resistance
genotypes
pcr
virus del mosaico de la cassava
marcadores genéticos
mapas genéticos
resistencia a la enfermedad
resistencia genética
genotipos
url https://hdl.handle.net/10568/42896
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