Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka
The global prevalence of chronic kidney disease (CKD) of uncertain etiology may be underreported. Communitylevel epidemiological studies are few due to the lack of national registries and poor focus on the reporting of noncommunicable diseases. Here we describe the prevalence of proteinuric-CKD and...
| Autores principales: | , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2011
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/40407 |
| _version_ | 1855523923428376576 |
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| author | Athuraliya, T.N.C. Abeysekera, D.T.D.J. Amerasinghe, Priyanie H. Kumarasiri, R. Bandara, P. Karunaratne , U. Milton, A.H. Jones, A.L. |
| author_browse | Abeysekera, D.T.D.J. Amerasinghe, Priyanie H. Athuraliya, T.N.C. Bandara, P. Jones, A.L. Karunaratne , U. Kumarasiri, R. Milton, A.H. |
| author_facet | Athuraliya, T.N.C. Abeysekera, D.T.D.J. Amerasinghe, Priyanie H. Kumarasiri, R. Bandara, P. Karunaratne , U. Milton, A.H. Jones, A.L. |
| author_sort | Athuraliya, T.N.C. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | The global prevalence of chronic kidney disease (CKD) of uncertain etiology may be underreported. Communitylevel epidemiological studies are few due to the lack of national registries and poor focus on the reporting of noncommunicable diseases. Here we describe the prevalence of proteinuric-CKD and disease characteristics of three rural populations in the North Central, Central, and Southern Provinces of Sri Lanka. Patients were selected using the random cluster sampling method and those older than 19 years of age were screened for persistent dipstick proteinuria. The prevalence of proteinuric-CKD in the Medawachchiya region (North Central) was 130 of 2600 patients, 68 of 709 patients in the Yatinuwara region (Central), and 66 of 2844 patients in the Hambantota region (Southern). The mean ages of these patients with CKD ranged from 44 to 52 years. Diabetes and long-standing hypertension were the main risk factors of CKD in the Yatinuwara and Hambantota regions. Age, exceeding 60 years, and farming were strongly associated with proteinuric-CKD in the Medawachchiya region; however, major risk factors were uncertain in 87% of these patients. Of these patients, 26 underwent renal biopsy; histology indicated tubulointerstitial disease. Thus, proteinuric-CKD of uncertain etiology is prevalent in the North Central Province of Sri Lanka. In contrast, known risk factors were associated with CKD in the Central and Southern Provinces. |
| format | Journal Article |
| id | CGSpace40407 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2011 |
| publishDateRange | 2011 |
| publishDateSort | 2011 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | CGSpace404072025-06-17T08:23:38Z Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka Athuraliya, T.N.C. Abeysekera, D.T.D.J. Amerasinghe, Priyanie H. Kumarasiri, R. Bandara, P. Karunaratne , U. Milton, A.H. Jones, A.L. public health kidney diseases rural areas proteinuria aetiology risks models surveys wastewater contamination water pollution The global prevalence of chronic kidney disease (CKD) of uncertain etiology may be underreported. Communitylevel epidemiological studies are few due to the lack of national registries and poor focus on the reporting of noncommunicable diseases. Here we describe the prevalence of proteinuric-CKD and disease characteristics of three rural populations in the North Central, Central, and Southern Provinces of Sri Lanka. Patients were selected using the random cluster sampling method and those older than 19 years of age were screened for persistent dipstick proteinuria. The prevalence of proteinuric-CKD in the Medawachchiya region (North Central) was 130 of 2600 patients, 68 of 709 patients in the Yatinuwara region (Central), and 66 of 2844 patients in the Hambantota region (Southern). The mean ages of these patients with CKD ranged from 44 to 52 years. Diabetes and long-standing hypertension were the main risk factors of CKD in the Yatinuwara and Hambantota regions. Age, exceeding 60 years, and farming were strongly associated with proteinuric-CKD in the Medawachchiya region; however, major risk factors were uncertain in 87% of these patients. Of these patients, 26 underwent renal biopsy; histology indicated tubulointerstitial disease. Thus, proteinuric-CKD of uncertain etiology is prevalent in the North Central Province of Sri Lanka. In contrast, known risk factors were associated with CKD in the Central and Southern Provinces. 2011-12 2014-06-13T14:47:36Z 2014-06-13T14:47:36Z Journal Article https://hdl.handle.net/10568/40407 en Limited Access Elsevier Athuraliya, N. T. C.; Abeysekera, T. D. J.; Amerasinghe, Priyanie.; Kumarasiri, R.; Bandara, P.; Karunaratne , U.; Milton, A. H.; Jones, A. L. 2011. Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka. Kidney International, 80(11):1212-1221. doi: https://doi.org/10.1038/ki.2011.258 |
| spellingShingle | public health kidney diseases rural areas proteinuria aetiology risks models surveys wastewater contamination water pollution Athuraliya, T.N.C. Abeysekera, D.T.D.J. Amerasinghe, Priyanie H. Kumarasiri, R. Bandara, P. Karunaratne , U. Milton, A.H. Jones, A.L. Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka |
| title | Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka |
| title_full | Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka |
| title_fullStr | Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka |
| title_full_unstemmed | Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka |
| title_short | Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka |
| title_sort | uncertain etiologies of proteinuric chronic kidney disease in rural sri lanka |
| topic | public health kidney diseases rural areas proteinuria aetiology risks models surveys wastewater contamination water pollution |
| url | https://hdl.handle.net/10568/40407 |
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