Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers

Introduction: With the renewed drive towards malaria elimination, there is a need for improved surveillance tools. While time series analysis is an important tool for surveillance, prediction and for measuring interventions' impact, approximations by commonly used Gaussian methods are prone to inacc...

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Main Authors: Briet, Olivier J.T., Amerasinghe, Priyanie H., Vounatsou, Penelope
Format: Journal Article
Language:Inglés
Published: Public Library of Science 2013
Subjects:
Online Access:https://hdl.handle.net/10568/40218
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author Briet, Olivier J.T.
Amerasinghe, Priyanie H.
Vounatsou, Penelope
author_browse Amerasinghe, Priyanie H.
Briet, Olivier J.T.
Vounatsou, Penelope
author_facet Briet, Olivier J.T.
Amerasinghe, Priyanie H.
Vounatsou, Penelope
author_sort Briet, Olivier J.T.
collection Repository of Agricultural Research Outputs (CGSpace)
description Introduction: With the renewed drive towards malaria elimination, there is a need for improved surveillance tools. While time series analysis is an important tool for surveillance, prediction and for measuring interventions' impact, approximations by commonly used Gaussian methods are prone to inaccuracies when case counts are low. Therefore, statistical methods appropriate for count data are required, especially during ''consolidation'' and ''pre-elimination'' phases. Methods: Generalized autoregressive moving average (GARMA) models were extended to generalized seasonal autoregressive integrated moving average (GSARIMA) models for parsimonious observation-driven modelling of non Gaussian, non stationary and/or seasonal time series of count data. The models were applied to monthly malaria case time series in a district in Sri Lanka, where malaria has decreased dramatically in recent years. Results: The malaria series showed long-term changes in the mean, unstable variance and seasonality. After fitting negativebinomial Bayesian models, both a GSARIMA and a GARIMA deterministic seasonality model were selected based on different criteria. Posterior predictive distributions indicated that negative-binomial models provided better predictions than Gaussian models, especially when counts were low. The G(S)ARIMA models were able to capture the autocorrelation in the series. Conclusions: G(S)ARIMA models may be particularly useful in the drive towards malaria elimination, since episode count series are often seasonal and non-stationary, especially when control is increased. Although building and fitting GSARIMA models is laborious, they may provide more realistic prediction distributions than do Gaussian methods and may be more suitable when counts are low.
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spelling CGSpace402182025-06-17T08:23:21Z Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers Briet, Olivier J.T. Amerasinghe, Priyanie H. Vounatsou, Penelope malaria time series analysis statistical methods regression analysis models rain case studies Introduction: With the renewed drive towards malaria elimination, there is a need for improved surveillance tools. While time series analysis is an important tool for surveillance, prediction and for measuring interventions' impact, approximations by commonly used Gaussian methods are prone to inaccuracies when case counts are low. Therefore, statistical methods appropriate for count data are required, especially during ''consolidation'' and ''pre-elimination'' phases. Methods: Generalized autoregressive moving average (GARMA) models were extended to generalized seasonal autoregressive integrated moving average (GSARIMA) models for parsimonious observation-driven modelling of non Gaussian, non stationary and/or seasonal time series of count data. The models were applied to monthly malaria case time series in a district in Sri Lanka, where malaria has decreased dramatically in recent years. Results: The malaria series showed long-term changes in the mean, unstable variance and seasonality. After fitting negativebinomial Bayesian models, both a GSARIMA and a GARIMA deterministic seasonality model were selected based on different criteria. Posterior predictive distributions indicated that negative-binomial models provided better predictions than Gaussian models, especially when counts were low. The G(S)ARIMA models were able to capture the autocorrelation in the series. Conclusions: G(S)ARIMA models may be particularly useful in the drive towards malaria elimination, since episode count series are often seasonal and non-stationary, especially when control is increased. Although building and fitting GSARIMA models is laborious, they may provide more realistic prediction distributions than do Gaussian methods and may be more suitable when counts are low. 2013 2014-06-13T14:47:11Z 2014-06-13T14:47:11Z Journal Article https://hdl.handle.net/10568/40218 en Open Access Public Library of Science Briet, O. J. T.; Amerasinghe, Priyanie H.; Vounatsou, P. 2013. Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers. PLoS One, 8(6):e65761-e65761. doi: https://doi.org/10.1371/journal.pone.0065761
spellingShingle malaria
time series analysis
statistical methods
regression analysis
models
rain
case studies
Briet, Olivier J.T.
Amerasinghe, Priyanie H.
Vounatsou, Penelope
Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers
title Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers
title_full Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers
title_fullStr Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers
title_full_unstemmed Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers
title_short Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers
title_sort generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers
topic malaria
time series analysis
statistical methods
regression analysis
models
rain
case studies
url https://hdl.handle.net/10568/40218
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