Toward community standards in the quest for orthologs

The identification of orthologs—genes pairs descended from a common ancestor through speciation, rather than duplication—has emerged as an essential component of many bioinformatics applications, ranging from the annotation of new genomes to experimental target prioritization. Yet, the development a...

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Main Authors: Dessimoz, C., Gabaldon, T., Roos, D.S., Sonnhammer, E., Herrero, J., Quest for Ortholog Consortium
Format: Journal Article
Language:Inglés
Published: Oxford University Press 2012
Subjects:
Online Access:https://hdl.handle.net/10568/35840
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author Dessimoz, C.
Gabaldon, T.
Roos, D.S.
Sonnhammer, E.
Herrero, J.
Quest for Ortholog Consortium
author_browse Dessimoz, C.
Gabaldon, T.
Herrero, J.
Quest for Ortholog Consortium
Roos, D.S.
Sonnhammer, E.
author_facet Dessimoz, C.
Gabaldon, T.
Roos, D.S.
Sonnhammer, E.
Herrero, J.
Quest for Ortholog Consortium
author_sort Dessimoz, C.
collection Repository of Agricultural Research Outputs (CGSpace)
description The identification of orthologs—genes pairs descended from a common ancestor through speciation, rather than duplication—has emerged as an essential component of many bioinformatics applications, ranging from the annotation of new genomes to experimental target prioritization. Yet, the development and application of orthology inference methods is hampered by the lack of consensus on source proteomes, file formats and benchmarks. The second ‘Quest for Orthologs’ meeting brought together stakeholders from various communities to address these challenges. We report on achievements and outcomes of this meeting, focusing on topics of particular relevance to the research community at large. The Quest for Orthologs consortium is an open community that welcomes contributions from all researchers interested in orthology research and applications.Contact: dessimoz@ebi.ac.uk
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spelling CGSpace358402025-11-12T05:45:47Z Toward community standards in the quest for orthologs Dessimoz, C. Gabaldon, T. Roos, D.S. Sonnhammer, E. Herrero, J. Quest for Ortholog Consortium bioinformatics genomes identification standards The identification of orthologs—genes pairs descended from a common ancestor through speciation, rather than duplication—has emerged as an essential component of many bioinformatics applications, ranging from the annotation of new genomes to experimental target prioritization. Yet, the development and application of orthology inference methods is hampered by the lack of consensus on source proteomes, file formats and benchmarks. The second ‘Quest for Orthologs’ meeting brought together stakeholders from various communities to address these challenges. We report on achievements and outcomes of this meeting, focusing on topics of particular relevance to the research community at large. The Quest for Orthologs consortium is an open community that welcomes contributions from all researchers interested in orthology research and applications.Contact: dessimoz@ebi.ac.uk 2012-03-15 2014-06-10T09:06:29Z 2014-06-10T09:06:29Z Journal Article https://hdl.handle.net/10568/35840 en Open Access application/pdf Oxford University Press Dessimoz, C.; Gabaldon, T.; Roos, D.S.; Sonnhammer, E.; Herrero, J.; Quest for Ortholog Consortium [includes Rouard, M.] -2012-Toward community standards in the quest for orthologs-Bioinformatics 28(6)-p. 900-904
spellingShingle bioinformatics
genomes
identification
standards
Dessimoz, C.
Gabaldon, T.
Roos, D.S.
Sonnhammer, E.
Herrero, J.
Quest for Ortholog Consortium
Toward community standards in the quest for orthologs
title Toward community standards in the quest for orthologs
title_full Toward community standards in the quest for orthologs
title_fullStr Toward community standards in the quest for orthologs
title_full_unstemmed Toward community standards in the quest for orthologs
title_short Toward community standards in the quest for orthologs
title_sort toward community standards in the quest for orthologs
topic bioinformatics
genomes
identification
standards
url https://hdl.handle.net/10568/35840
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