At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study
Low HDL-cholesterol (HDL-C), using as cut-offs 1.03 mmol/L in men and 1.29 mmol/L in women, was observed in more than 25% apparently healthy adults (n = 541) in a cross-sectional study on nutrition transition and cardiometabolic risk factors (CMRF) in Benin, West Africa. Both overweight/obesity (35....
| Autores principales: | , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
MDPI
2013
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/35531 |
| _version_ | 1855513564398223360 |
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| author | Delisle, H. Ntandou, G. Sodjinou, R. Couillard, C. Despres, J. |
| author_browse | Couillard, C. Delisle, H. Despres, J. Ntandou, G. Sodjinou, R. |
| author_facet | Delisle, H. Ntandou, G. Sodjinou, R. Couillard, C. Despres, J. |
| author_sort | Delisle, H. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Low HDL-cholesterol (HDL-C), using as cut-offs 1.03 mmol/L in men and 1.29 mmol/L in women, was observed in more than 25% apparently healthy adults (n = 541) in a cross-sectional study on nutrition transition and cardiometabolic risk factors (CMRF) in Benin, West Africa. Both overweight/obesity (35.3%) and underweight (11.3%) were present, displaying the double burden of malnutrition. We examined in more depth the association of low HDL-C with nutrition and with other CMRF. Metabolic syndrome components were assessed, plus the ratio of total cholesterol (TC)/HDL-C and serum homocysteine. Insulin resistance was based on Homeostasis Model Assessment. We also measured BMI and body composition by bio-impedance. Dietary quality was appraised with two non-consecutive 24 h recalls. Low HDL-C was associated with much higher TC/HDL-C and more abdominal obesity in men and women and with more insulin resistance in women. The rate of low HDL-C was highest (41.9%) among the overweight/obese subjects (BMI ≥ 25), but it also reached 31.1% among the underweight (BMI < 18.5), compared with 17.3% among normal-weight subjects (p < 0.001). Lower dietary micronutrient adequacy, in particular, in vitamins A, B3, B12, zinc and calcium, was associated with low HDL-C when controlling for several confounders. This suggests that at-risk lipoprotein cholesterol may be associated with either underweight or overweight/obesity and with poor micronutrient intake. |
| format | Journal Article |
| id | CGSpace35531 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2013 |
| publishDateRange | 2013 |
| publishDateSort | 2013 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | CGSpace355312025-11-12T05:36:55Z At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study Delisle, H. Ntandou, G. Sodjinou, R. Couillard, C. Despres, J. cholesterol diet malnutrition nutritional status food science Low HDL-cholesterol (HDL-C), using as cut-offs 1.03 mmol/L in men and 1.29 mmol/L in women, was observed in more than 25% apparently healthy adults (n = 541) in a cross-sectional study on nutrition transition and cardiometabolic risk factors (CMRF) in Benin, West Africa. Both overweight/obesity (35.3%) and underweight (11.3%) were present, displaying the double burden of malnutrition. We examined in more depth the association of low HDL-C with nutrition and with other CMRF. Metabolic syndrome components were assessed, plus the ratio of total cholesterol (TC)/HDL-C and serum homocysteine. Insulin resistance was based on Homeostasis Model Assessment. We also measured BMI and body composition by bio-impedance. Dietary quality was appraised with two non-consecutive 24 h recalls. Low HDL-C was associated with much higher TC/HDL-C and more abdominal obesity in men and women and with more insulin resistance in women. The rate of low HDL-C was highest (41.9%) among the overweight/obese subjects (BMI ≥ 25), but it also reached 31.1% among the underweight (BMI < 18.5), compared with 17.3% among normal-weight subjects (p < 0.001). Lower dietary micronutrient adequacy, in particular, in vitamins A, B3, B12, zinc and calcium, was associated with low HDL-C when controlling for several confounders. This suggests that at-risk lipoprotein cholesterol may be associated with either underweight or overweight/obesity and with poor micronutrient intake. 2013 2014-05-05T08:44:19Z 2014-05-05T08:44:19Z Journal Article https://hdl.handle.net/10568/35531 en Open Access application/pdf MDPI Delisle, H.; Ntandou, G.; Sodjinou, R.; Couillard, C.; Despres, J. -2013-At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study-Nutrients 5-p. 1366-1383 |
| spellingShingle | cholesterol diet malnutrition nutritional status food science Delisle, H. Ntandou, G. Sodjinou, R. Couillard, C. Despres, J. At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study |
| title | At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study |
| title_full | At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study |
| title_fullStr | At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study |
| title_full_unstemmed | At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study |
| title_short | At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study |
| title_sort | at risk serum cholesterol profile at both ends of the nutrition spectrum in west african adults the benin study |
| topic | cholesterol diet malnutrition nutritional status food science |
| url | https://hdl.handle.net/10568/35531 |
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