Rational identification of an optimal antibody mixture for targeting the epidermal growth factor receptor
The epidermal growth factor receptor (EGFR) is frequently dysregulated in human malignancies and a validated target for cancer therapy. Two monoclonal anti-EGFR antibodies (cetuximab and panitumumab) are approved for clinical use. However, the percentage of patients responding to treatment is low an...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Informa UK Limited
2011
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/35344 |
Similar Items: Rational identification of an optimal antibody mixture for targeting the epidermal growth factor receptor
- Activation of peroxisome proliferator–activated receptor gamma induces anti-inflammatory properties in the chicken free avian respiratory macrophages
- Structure, ultrastructure and cation accumulation in quinoa epidermal bladder cell complex under high saline stress
- Suppression of interleukin 2 secretion and interleukin 2 receptor expression during tsetse-transmitted trypanosomiasis in cattle
- Crop performance in complex mixtures: melon and okra in cassava-maize mixture
- Combined epidermal growth factor and hyaluronic acid supplementation of in vitro maturation medium and its impact on bovine oocyte proteome and competence
- Prevalence of toxin-producing strains and antimicrobial resistance in isolates of Staphylococcus hyicus from pigs with exudative epidermitis and from healthy pigs