Genetic control of resistance to trypanosomiasis
To map the genetic sources of trypanotolerance in mice, a linkage analysis of survival following trypanosome challenge was performed by selective genotyping in a large F2 population produced by crossing the resistant C57BL/6 and susceptible BALB/c inbred mouse lines. We report evidence of a chromoso...
| Autores principales: | , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
1996
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/35333 |
| _version_ | 1855542565336514560 |
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| author | Kemp, Stephen J. Darvasi, A. Soller, M. Teale, A.J. |
| author_browse | Darvasi, A. Kemp, Stephen J. Soller, M. Teale, A.J. |
| author_facet | Kemp, Stephen J. Darvasi, A. Soller, M. Teale, A.J. |
| author_sort | Kemp, Stephen J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | To map the genetic sources of trypanotolerance in mice, a linkage analysis of survival following trypanosome challenge was performed by selective genotyping in a large F2 population produced by crossing the resistant C57BL/6 and susceptible BALB/c inbred mouse lines. We report evidence of a chromosomal region of large effect, possibly comprising more than one resistance locus, on Chromosome 17; and of further loci on Chromosomes 1 and 5. Together, these genes can account for all of the difference between the mean parental phenotypes. |
| format | Journal Article |
| id | CGSpace35333 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1996 |
| publishDateRange | 1996 |
| publishDateSort | 1996 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | CGSpace353332024-08-27T12:27:43Z Genetic control of resistance to trypanosomiasis Kemp, Stephen J. Darvasi, A. Soller, M. Teale, A.J. animal diseases livestock trypanosomiasis genetics To map the genetic sources of trypanotolerance in mice, a linkage analysis of survival following trypanosome challenge was performed by selective genotyping in a large F2 population produced by crossing the resistant C57BL/6 and susceptible BALB/c inbred mouse lines. We report evidence of a chromosomal region of large effect, possibly comprising more than one resistance locus, on Chromosome 17; and of further loci on Chromosomes 1 and 5. Together, these genes can account for all of the difference between the mean parental phenotypes. 1996-11 2014-04-14T10:56:01Z 2014-04-14T10:56:01Z Journal Article https://hdl.handle.net/10568/35333 en Limited Access Elsevier Kemp, S.J., Darvasi, A., Soller, M. and Teale, A.J. 1996. Genetic control of resistance to trypanosomiasis. Veterinary Immunology and Immunopathology 54(1-4): 239-243. |
| spellingShingle | animal diseases livestock trypanosomiasis genetics Kemp, Stephen J. Darvasi, A. Soller, M. Teale, A.J. Genetic control of resistance to trypanosomiasis |
| title | Genetic control of resistance to trypanosomiasis |
| title_full | Genetic control of resistance to trypanosomiasis |
| title_fullStr | Genetic control of resistance to trypanosomiasis |
| title_full_unstemmed | Genetic control of resistance to trypanosomiasis |
| title_short | Genetic control of resistance to trypanosomiasis |
| title_sort | genetic control of resistance to trypanosomiasis |
| topic | animal diseases livestock trypanosomiasis genetics |
| url | https://hdl.handle.net/10568/35333 |
| work_keys_str_mv | AT kempstephenj geneticcontrolofresistancetotrypanosomiasis AT darvasia geneticcontrolofresistancetotrypanosomiasis AT sollerm geneticcontrolofresistancetotrypanosomiasis AT tealeaj geneticcontrolofresistancetotrypanosomiasis |