Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle

Sons (n = 71 to 75) of each of six Holstein sires were genotyped at 69 microsatellite loci covering a total of 676 cM on chromosomes 3, 5, 9, 10, 13, 15, 17, 20, 23, and 26. Estimates of quantitative trait loci (QTL) effect and location were made using a least squares interval mapping approach based...

Full description

Bibliographic Details
Main Authors: Plante, Y., Gibson, John P., Nadesalingam, J., Mehrabani-Yeganeh, H., Lefebvre, S., Vandervoort, G., Jansen, G.B.
Format: Journal Article
Language:Inglés
Published: American Dairy Science Association 2001
Subjects:
Online Access:https://hdl.handle.net/10568/35325
_version_ 1855531655393968128
author Plante, Y.
Gibson, John P.
Nadesalingam, J.
Mehrabani-Yeganeh, H.
Lefebvre, S.
Vandervoort, G.
Jansen, G.B.
author_browse Gibson, John P.
Jansen, G.B.
Lefebvre, S.
Mehrabani-Yeganeh, H.
Nadesalingam, J.
Plante, Y.
Vandervoort, G.
author_facet Plante, Y.
Gibson, John P.
Nadesalingam, J.
Mehrabani-Yeganeh, H.
Lefebvre, S.
Vandervoort, G.
Jansen, G.B.
author_sort Plante, Y.
collection Repository of Agricultural Research Outputs (CGSpace)
description Sons (n = 71 to 75) of each of six Holstein sires were genotyped at 69 microsatellite loci covering a total of 676 cM on chromosomes 3, 5, 9, 10, 13, 15, 17, 20, 23, and 26. Estimates of quantitative trait loci (QTL) effect and location were made using a least squares interval mapping approach based on daughter yield deviations of sons for 305 d milk, fat, and protein yield and fat and protein percentage. Thresholds for statistical significance of QTL effects were determined from interval mapping of 10,000 random permutations of the data across the bull sire families and within each sire family separately. Analyses combining data across sires indicated the presence of QTL affecting milk, fat, and protein yield on chromosomes 20 and 26 and a QTL affecting fat and protein percentage on chromosome 3. Analyses within each sire family separately indicated the presence of segregating QTL in at least one family on 7 of the 10 chromosomes. Statistically significant estimates of QTL effects on breeding value ranged from 438 to 658 kg of milk, from 17.4 to 24.9 kg of fat, 13.0 to 17.0 kg of protein, 0.04 to 0.17% fat, and 0.07 to 0.10% protein.
format Journal Article
id CGSpace35325
institution CGIAR Consortium
language Inglés
publishDate 2001
publishDateRange 2001
publishDateSort 2001
publisher American Dairy Science Association
publisherStr American Dairy Science Association
record_format dspace
spelling CGSpace353252024-11-15T08:52:46Z Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle Plante, Y. Gibson, John P. Nadesalingam, J. Mehrabani-Yeganeh, H. Lefebvre, S. Vandervoort, G. Jansen, G.B. cattle genetics milk production Sons (n = 71 to 75) of each of six Holstein sires were genotyped at 69 microsatellite loci covering a total of 676 cM on chromosomes 3, 5, 9, 10, 13, 15, 17, 20, 23, and 26. Estimates of quantitative trait loci (QTL) effect and location were made using a least squares interval mapping approach based on daughter yield deviations of sons for 305 d milk, fat, and protein yield and fat and protein percentage. Thresholds for statistical significance of QTL effects were determined from interval mapping of 10,000 random permutations of the data across the bull sire families and within each sire family separately. Analyses combining data across sires indicated the presence of QTL affecting milk, fat, and protein yield on chromosomes 20 and 26 and a QTL affecting fat and protein percentage on chromosome 3. Analyses within each sire family separately indicated the presence of segregating QTL in at least one family on 7 of the 10 chromosomes. Statistically significant estimates of QTL effects on breeding value ranged from 438 to 658 kg of milk, from 17.4 to 24.9 kg of fat, 13.0 to 17.0 kg of protein, 0.04 to 0.17% fat, and 0.07 to 0.10% protein. 2001-06 2014-04-14T10:55:59Z 2014-04-14T10:55:59Z Journal Article https://hdl.handle.net/10568/35325 en Limited Access American Dairy Science Association Plante, Y., Gibson, J.P., Nadesalingam, J., Mehrabani-Yeganeh, H., Lefebvre, S., Vandervoort, G. and Jansen, G.B. 2001. Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle. Journal of Dairy Science 84(6): 1516-1524.
spellingShingle cattle
genetics
milk production
Plante, Y.
Gibson, John P.
Nadesalingam, J.
Mehrabani-Yeganeh, H.
Lefebvre, S.
Vandervoort, G.
Jansen, G.B.
Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle
title Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle
title_full Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle
title_fullStr Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle
title_full_unstemmed Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle
title_short Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle
title_sort detection of quantitative trait loci affecting milk production traits on 10 chromosomes in holstein cattle
topic cattle
genetics
milk production
url https://hdl.handle.net/10568/35325
work_keys_str_mv AT plantey detectionofquantitativetraitlociaffectingmilkproductiontraitson10chromosomesinholsteincattle
AT gibsonjohnp detectionofquantitativetraitlociaffectingmilkproductiontraitson10chromosomesinholsteincattle
AT nadesalingamj detectionofquantitativetraitlociaffectingmilkproductiontraitson10chromosomesinholsteincattle
AT mehrabaniyeganehh detectionofquantitativetraitlociaffectingmilkproductiontraitson10chromosomesinholsteincattle
AT lefebvres detectionofquantitativetraitlociaffectingmilkproductiontraitson10chromosomesinholsteincattle
AT vandervoortg detectionofquantitativetraitlociaffectingmilkproductiontraitson10chromosomesinholsteincattle
AT jansengb detectionofquantitativetraitlociaffectingmilkproductiontraitson10chromosomesinholsteincattle