Trypanosoma congolense infection in sheep: Ultrastructural changes in the skin prior to development of local skin reactions

Events occurring in the skin of sheep prior to development of Trypanosoma congolense-induced local skin reactions (chancres) were studied using electron microscopy. Three days after infection, few trypanosomes were present in the dermal collagen. However, these parasites were more abundant 5 days af...

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Bibliographic Details
Main Authors: Mwangi, David Miano, Hopkins, J., Luckins, A.G.
Format: Journal Article
Language:Inglés
Published: Elsevier 1995
Subjects:
Online Access:https://hdl.handle.net/10568/35261
Description
Summary:Events occurring in the skin of sheep prior to development of Trypanosoma congolense-induced local skin reactions (chancres) were studied using electron microscopy. Three days after infection, few trypanosomes were present in the dermal collagen. However, these parasites were more abundant 5 days after infection, and were also found in dermal lymphatics and in the connective tissue matrix between collagen bundles. Mast cells in the skin obtained 5 days after infection showed evidence of degranulation. These events may play a role during the induction phase of trypanosomal chancres.